2022
Analysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials
Caruana DL, Kim D, Galivanche AR, David WB, Justen MA, Moushey AM, Sheth AH, Paranjpe MD, Grauer JN. Analysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials. Clinical Spine Surgery A Spine Publication 2022, 35: e596-e600. PMID: 35351841, DOI: 10.1097/bsd.0000000000001323.Peer-Reviewed Original ResearchConceptsClinical trialsTrial terminationTrial characteristicsMultivariate analysisCross-sectional analysisInvestigation of drugsInsufficient accrualResults databaseInterventional studyDetermine predictorsClinical studiesBACKGROUND DATACommon reasonAssess reasonsRecruitment statusTrialsPredictors of terminationSearch termsSpineCompletion ratesRegistryPredictorsStudyTermination
2014
Assessment of Routine Imaging Practices After Operatively Repaired Distal Radius and Scaphoid Fractures N/A - Not a clinical study
Bohl D, Lese A, Patterson J, Grauer J, Dodds S. Assessment of Routine Imaging Practices After Operatively Repaired Distal Radius and Scaphoid Fractures N/A - Not a clinical study. The Journal Of Hand Surgery 2014, 39: e41. DOI: 10.1016/j.jhsa.2014.06.088.Peer-Reviewed Original Research
2012
Lower-extremity weight-bearing compliance is maintained over time after biofeedback training.
Hustedt JW, Blizzard DJ, Baumgaertner MR, Leslie MP, Grauer JN. Lower-extremity weight-bearing compliance is maintained over time after biofeedback training. Orthopedics 2012, 35: e1644-8. PMID: 23127458, DOI: 10.3928/01477447-20121023-24.Peer-Reviewed Original ResearchConceptsWeight-bearing instructionsBiofeedback trainingWeight bearingProspective clinical studyLimited weight bearingAcademic orthopedic centerPotential clinical applicabilityOrthopedic centersClinical studiesClinical applicabilityControl participantsSignificant differencesImmediate effectsBiofeedback deviceTraining sessionsParticipantsOriginal testingComplianceVerbal instructionsImmediate complianceHoursRetention testPrevious studiesPatientsStudy
2010
Normal Functional Range of Motion of the Lumbar Spine During 15 Activities of Daily Living
Bible JE, Biswas D, Miller CP, Whang PG, Grauer JN. Normal Functional Range of Motion of the Lumbar Spine During 15 Activities of Daily Living. Clinical Spine Surgery A Spine Publication 2010, 23: 106-112. PMID: 20065869, DOI: 10.1097/bsd.0b013e3181981823.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultBiomechanical PhenomenaElectrodiagnosisFemaleHumansIntervertebral DiscLumbar VertebraeMaleMiddle AgedMovementOutcome Assessment, Health CareProspective StudiesRange of Motion, ArticularReference ValuesTask Performance and AnalysisYoung AdultZygapophyseal JointConceptsFull active ROMLumbar spineAsymptomatic subjectsActive ROMFunctional ROMDaily livingFlexion/extensionProspective clinical studyLateral bending radiographsDynamic flexion/extensionNormal functional rangeIntraclass correlation coefficientLumbar ROMPreoperative impairmentPostsurgical outcomesClinical studiesBACKGROUND DATALumbar rangeLumbar motionSpinal ROMConsecutive daysADLRadiographic measurementsSpineROM valuesNormal Functional Range of Motion of the Cervical Spine During 15 Activities of Daily Living
Bible JE, Biswas D, Miller CP, Whang PG, Grauer JN. Normal Functional Range of Motion of the Cervical Spine During 15 Activities of Daily Living. Clinical Spine Surgery A Spine Publication 2010, 23: 15-21. PMID: 20051924, DOI: 10.1097/bsd.0b013e3181981632.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAgedAnthropometryArthrographyArthrometry, ArticularBiomechanical PhenomenaCervical VertebraeCineradiographyFemaleHead MovementsHumansIntervertebral DiscMaleMiddle AgedMovementNeck MusclesProspective StudiesRange of Motion, ArticularReference ValuesYoung AdultZygapophyseal JointConceptsFull active ROMAsymptomatic subjectsCervical spineCervical ROMActive ROMFunctional ROMDaily livingFlexion/extensionProspective clinical studyLateral bending radiographsNormal cervical rangeDynamic flexion/extensionNormal functional rangeIntraclass correlation coefficientPreoperative impairmentCervical rangePostsurgical outcomesCervical motionClinical studiesBACKGROUND DATASpinal ROMConsecutive daysRadiographic measurementsADLGreater ROM
2008
Postoperative bracing after spine surgery for degenerative conditions: a questionnaire study
Bible JE, Biswas D, Whang PG, Simpson AK, Rechtine GR, Grauer JN. Postoperative bracing after spine surgery for degenerative conditions: a questionnaire study. The Spine Journal 2008, 9: 309-316. PMID: 18790685, DOI: 10.1016/j.spinee.2008.06.453.Peer-Reviewed Original ResearchConceptsSpine surgeonsPostoperative bracingSpinal proceduresSpecific spinal proceduresVariety of orthosesCervical spine proceduresAnterior cervical spineInstrumented lumbar fusionSingle-page questionnaireDuration of treatmentType of orthosisSpecific surgical proceduresQuestionnaire studyInternal fixationLumbar fusionCervical spineSpine surgeryClinical studiesSpine proceduresBracing protocolSurgical proceduresLumbar spineCommon reasonProper indicationsClinical experience
2007
The safety and utility of bone morphogenetic protein in anterior and posterior cervical-spine fusions
Lee R, White A, Grauer J. The safety and utility of bone morphogenetic protein in anterior and posterior cervical-spine fusions. Current Orthopaedic Practice 2007, 18: 270-275. DOI: 10.1097/bco.0b013e32810c00f6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCervical spine surgeryRecombinant human bone morphogenetic proteinHuman bone morphogenetic proteinAnterior cervical spine surgeryAutologous bone graft harvestPosterior cervical spine fusionBone morphogenetic proteinSoft tissue edemaProspective clinical studyCervical spine fusionHigh fusion rateBone graft harvestMorphogenetic proteinsLocal complicationsBone graft alternativesCervical fusionCohort studyBony unionCervical spineClinical studiesSurgical techniqueLumbar spineAppropriate dosePurpose of ReviewInterestLocal swelling
2006
Bone Morphogenetic Protein for Pseudarthrosis Repair in Revision Cervical Spine Surgery
White A, Lee R, Grauer J. Bone Morphogenetic Protein for Pseudarthrosis Repair in Revision Cervical Spine Surgery. Seminars In Spine Surgery 2006, 18: 207-210. DOI: 10.1053/j.semss.2006.09.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCervical spine surgeryRevision cervical spine surgeryAnterior cervical spine surgeryRecombinant human bone morphogenetic proteinSpine surgeryProspective clinical studyOff-label useBone morphogenetic proteinCervical surgeryBone graft alternativesPseudarthrosis repairClinical studiesSurgical techniqueAppropriate doseAnimal modelsSurgeryGraft alternativesHuman bone morphogenetic proteinMorphogenetic proteinsPotent osteoinductive factorsRecent reportsOsteoinductive factorsComplicationsPseudarthrosesDoseThe Contemporary Treatment of Odontoid Injuries
Maak TG, Grauer JN. The Contemporary Treatment of Odontoid Injuries. Spine 2006, 31: s53-s60. PMID: 16685237, DOI: 10.1097/01.brs.0000217941.55817.52.Peer-Reviewed Original ResearchConceptsType II fracturesOdontoid fracturesTreatment optionsOptimal treatmentAnterior odontoid fixationNonoperative treatment optionsII fracturesCervical spine fracturesOperative treatment optionsNoncontiguous fracturesOdontoid fixationNeurologic injurySpine fracturesAppropriate imagingCervical spineClinical studiesExternal immobilizationBACKGROUND DATAClinical problemContemporary treatmentInjuryCurrent conceptsPertinent literatureTreatmentType I
2001
Flexibility Analysis of Posterolateral Fusions in a New Zealand White Rabbit Model
Erulkar J, Grauer J, Patel T, Panjabi M. Flexibility Analysis of Posterolateral Fusions in a New Zealand White Rabbit Model. Spine 2001, 26: 1125-1130. PMID: 11413423, DOI: 10.1097/00007632-200105150-00006.Peer-Reviewed Original ResearchConceptsPosterolateral fusionRabbit modelAutogenous iliac crest bone graftIliac crest bone graftTime pointsNew Zealand white rabbitsPosterolateral lumbar fusionAdult New Zealand white rabbitsCrest bone graftNew Zealand white rabbit modelZealand white rabbitsHuman cadaveric studyPosterolateral spinal fusionWhite rabbit modelVivo rabbit modelIntertransverse process fusionLumbar fusionClinical studiesBACKGROUND DATASpinal fusionAnimal studiesCadaveric studyBone graftWhite rabbitsManual palpation