2013
Alleles of a Polymorphic ETV6 Binding Site in DCDC2 Confer Risk of Reading and Language Impairment
Powers NR, Eicher JD, Butter F, Kong Y, Miller LL, Ring SM, Mann M, Gruen JR. Alleles of a Polymorphic ETV6 Binding Site in DCDC2 Confer Risk of Reading and Language Impairment. American Journal Of Human Genetics 2013, 93: 19-28. PMID: 23746548, PMCID: PMC3710765, DOI: 10.1016/j.ajhg.2013.05.008.Peer-Reviewed Original ResearchMeSH KeywordsAllelesBase SequenceBinding SitesCase-Control StudiesDyslexiaGenetic Association StudiesHaplotypesHeLa CellsHumansLanguage Development DisordersLanguage TestsLinkage DisequilibriumMicrosatellite RepeatsMicrotubule-Associated ProteinsMolecular Sequence DataPhylogenyPolymorphism, GeneticPromoter Regions, GeneticProtein BindingProto-Oncogene Proteins c-etsRepressor ProteinsRisk Factors
2012
DCDC2 genetic variants and susceptibility to developmental dyslexia
Marino C, Meng H, Mascheretti S, Rusconi M, Cope N, Giorda R, Molteni M, Gruen JR. DCDC2 genetic variants and susceptibility to developmental dyslexia. Psychiatric Genetics 2012, 22: 25-30. PMID: 21881542, PMCID: PMC3232293, DOI: 10.1097/ypg.0b013e32834acdb2.Peer-Reviewed Original ResearchMeSH KeywordsDyslexiaGenetic Predisposition to DiseaseHumansMicrotubule-Associated ProteinsNeuropsychological TestsPhenotypePolymorphism, Single NucleotideConceptsDevelopmental dyslexiaQuantitative transmission disequilibrium test analysesNonword readingNonword spellingOrthographic choiceMarker-trait associationsQuantitative trait lociDyslexiaMemory impairmentRelated readingsTrait lociQuantitative traitsQuantitative transmission disequilibrium testTransmission disequilibrium test analysisPhenotypic complexityAssociation evidenceGenetic linkageMemoryAssociation analysisDCDC2WordsGenetic variantsTransmission disequilibrium testReadingPerformance tests
2010
A Dyslexia-Associated Variant in DCDC2 Changes Gene Expression
Meng H, Powers NR, Tang L, Cope NA, Zhang PX, Fuleihan R, Gibson C, Page GP, Gruen JR. A Dyslexia-Associated Variant in DCDC2 Changes Gene Expression. Behavior Genetics 2010, 41: 58-66. PMID: 21042874, PMCID: PMC3053575, DOI: 10.1007/s10519-010-9408-3.Peer-Reviewed Original Research