2024
Mediators of sex-specific differences in rates of stroke mimics among patients treated with intravenous thrombolysis: A nationwide analysis of 174,995 patients
Chen H, Khunte M, Colasurdo M, Chaturvedi S, Malhotra A, Gandhi D. Mediators of sex-specific differences in rates of stroke mimics among patients treated with intravenous thrombolysis: A nationwide analysis of 174,995 patients. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 108021. PMID: 39303869, DOI: 10.1016/j.jstrokecerebrovasdis.2024.108021.Peer-Reviewed Original ResearchRate of migraineNo cerebral infarctionPatients treated with intravenous thrombolysisRisk factorsIntravenous thrombolysisStroke mimicsMediation analysisICD-10 codesVascular risk factorsRetrospective cohort studyNational Inpatient Sample databaseIVT-treated patientsRates of stroke mimicsInpatient Sample databaseICD-10Cohort studyFemale patientsDemographic informationSex-specific differencesNationwide analysisCerebral infarctionPatientsSample databaseWomenMigraineSex Discrepancies in the Population Incidence of Stroke and Hemorrhage Related to Atrial Fibrillation or Flutter
Khunte M, Chen H, Colasurdo M, Chaturvedi S, Malhotra A, Gandhi D. Sex Discrepancies in the Population Incidence of Stroke and Hemorrhage Related to Atrial Fibrillation or Flutter. Cerebrovascular Diseases 2024, 1-6. PMID: 38432203, DOI: 10.1159/000538108.Peer-Reviewed Original ResearchAF-related ischemic strokeIschemic strokeAssociated with higher stroke riskIschemic stroke hospitalizationsRisk factorsAF-related strokeICD-10 codesRisk of hospitalizationVascular risk factorsRates of anticoagulant useHigher stroke riskIncidence of hospitalizationNational Inpatient SampleHigher stroke severityUnited States Census BureauIncidence of strokeAtrial fibrillationPatient demographic informationStroke hospitalizationsStroke characteristicsRelative riskICD-10Population incidenceRates of large vessel occlusionsRisk of morbidityUncertainty-aware deep-learning model for prediction of supratentorial hematoma expansion from admission non-contrast head computed tomography scan
Tran A, Zeevi T, Haider S, Abou Karam G, Berson E, Tharmaseelan H, Qureshi A, Sanelli P, Werring D, Malhotra A, Petersen N, de Havenon A, Falcone G, Sheth K, Payabvash S. Uncertainty-aware deep-learning model for prediction of supratentorial hematoma expansion from admission non-contrast head computed tomography scan. Npj Digital Medicine 2024, 7: 26. PMID: 38321131, PMCID: PMC10847454, DOI: 10.1038/s41746-024-01007-w.Peer-Reviewed Original ResearchDeep learning modelsHematoma expansionIntracerebral hemorrhageICH expansionComputed tomographyNon-contrast head CTNon-contrast head computed tomographyHigh risk of HEHead computed tomographyHigh-confidence predictionsRisk of HENon-contrast headReceiver operating characteristic areaModifiable risk factorsMonte Carlo dropoutOperating characteristics areaPotential treatment targetHead CTVisual markersIdentified patientsAutomated deep learning modelDataset of patientsRisk factorsHigh riskPatientsTime-Dependent Changes in Hematoma Expansion Rate after Supratentorial Intracerebral Hemorrhage and Its Relationship with Neurological Deterioration and Functional Outcome
Karam G, Chen M, Zeevi D, Harms B, Torres-Lopez V, Rivier C, Malhotra A, de Havenon A, Falcone G, Sheth K, Payabvash S. Time-Dependent Changes in Hematoma Expansion Rate after Supratentorial Intracerebral Hemorrhage and Its Relationship with Neurological Deterioration and Functional Outcome. Diagnostics 2024, 14: 308. PMID: 38337824, PMCID: PMC10855868, DOI: 10.3390/diagnostics14030308.Peer-Reviewed Original ResearchPredictors of NDSupratentorial intracerebral hemorrhageHematoma expansionIntracerebral hemorrhageNeurological deteriorationPoor outcomeNIH Stroke ScalePost-ICHFunctional outcomesMild symptomsHematoma expansion ratesIntracerebral hemorrhage onsetAssociation of HEModifiable risk factorsGlasgow Coma ScaleBaseline CTHematoma growthConsecutive patientsHead CTSCAN-3Follow-upRate of HEComa ScaleRisk factorsHematoma
2022
Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke
Chen H, Khunte M, Colasurdo M, Jindal G, Malhotra A, Gandhi D, Chaturvedi S. Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke. Stroke 2022, 54: 518-526. PMID: 36541211, DOI: 10.1161/strokeaha.122.041749.Peer-Reviewed Original ResearchConceptsMultivariable logistic regression modelEndovascular thrombectomyAssociation of osteoarthritisLogistic regression modelsHospital mortalityMedical comorbiditiesIschemic strokeRisk factorsLower oddsLarge vessel acute ischemic strokeNational Inpatient Sample databaseMultivariable logistic regression analysisLarge-vessel ischemic strokeIntravenous thrombolysis treatmentStroke risk factorsAcute ischemic strokeIschemic stroke patientsPresence of osteoarthritisCause of disabilityCross-sectional studyLogistic regression analysisPatient selection practicesLarge-scale cross-sectional studyDirect risk factorEVT treatment
2019
Screening for Intracranial Aneurysms in Patients with Thoracic Aortic Aneurysms
Malhotra A, Seifert K, Wu X, Matouk C, Elefteriades JA. Screening for Intracranial Aneurysms in Patients with Thoracic Aortic Aneurysms. Cerebrovascular Diseases 2019, 47: 253-259. PMID: 31412341, DOI: 10.1159/000501194.Peer-Reviewed Original ResearchConceptsPrevalence of IAsThoracic aortic aneurysmIntracranial aneurysmsRetrospective studyAortic aneurysmRisk factorsPrevious retrospective studySignificant risk factorsPotential risk factorsMagnetic resonance angiogramStudent's t-testPatient demographicsUnivariate analysisHigh prevalenceLarge cohortGeneral populationPatientsAneurysmsPrevalenceCategorical variablesΧ2 testHypertensionT-testContinuous variablesIA locationA comparison of benign positional vertigo and stroke patients presenting to the emergency department with vertigo or dizziness
Hanna J, Malhotra A, Brauer PR, Luryi A, Michaelides E. A comparison of benign positional vertigo and stroke patients presenting to the emergency department with vertigo or dizziness. American Journal Of Otolaryngology 2019, 40: 102263. PMID: 31358317, DOI: 10.1016/j.amjoto.2019.07.007.Peer-Reviewed Original ResearchConceptsBenign paroxysmal positional vertigoStroke risk factorsCT/CTAEmergency departmentBPPV patientsNeurologic symptomsStroke patientsRisk factorsPositional vertigoCT headExam findingsNeurologic exam findingsPosterior circulation strokeProfile of patientsBenign positional vertigoParoxysmal positional vertigoCommon imaging modalityAcute strokeNeurologic examInitial imagingMRI brainDischarge diagnosisComputed tomographyPatientsVertigoNeuroimaging of Pediatric Arteriopathies
Goyal P, Malhotra A, Almast J, Sapire J, Gupta S, Mangla M, Mangla R. Neuroimaging of Pediatric Arteriopathies. Journal Of Neuroimaging 2019, 29: 287-308. PMID: 30920080, DOI: 10.1111/jon.12614.Peer-Reviewed Original ResearchConceptsIschemic strokeMajor prognostic implicationsPediatric ischemic strokeSecondary stroke preventionAcute ischemic strokeFocal neurologic deficitsAdult stroke populationSmall vessel arteriopathyNoninflammatory etiologiesRecurrent strokeStroke preventionSystemic complicationsCerebral arteriopathyNeurologic deficitsStroke etiologyAcute managementPrompt diagnosisStroke populationNeuropsychiatric symptomsClinical manifestationsClinical symptomsPrognostic implicationsPredominant vesselRisk factorsSchool-aged children
2016
The Use of High-Risk Criteria in Screening Patients for Blunt Cerebrovascular Injury A Survey
Wu X, Malhotra A, Forman HP, Nunez D, Sanelli P. The Use of High-Risk Criteria in Screening Patients for Blunt Cerebrovascular Injury A Survey. Academic Radiology 2016, 24: 456-461. PMID: 27979639, DOI: 10.1016/j.acra.2016.11.010.Peer-Reviewed Original ResearchMeSH KeywordsAttitude of Health PersonnelCerebral AngiographyCerebrovascular TraumaComputed Tomography AngiographyDatabases, FactualDelayed DiagnosisEmergency Service, HospitalHumansMagnetic Resonance AngiographyMass ScreeningRadiologistsRisk AssessmentRisk FactorsSurveys and QuestionnairesUnited StatesWounds, NonpenetratingConceptsBlunt cerebrovascular injuryRisk factorsEmergency departmentCT angiographyDenver criteriaMR angiographyC1-C3 fracturesUtilization of imagingCerebrovascular injuryBlunt injuryBlunt traumaScreening ratesAngiographic studiesLarge academic institutionVascular injuryScreening patientsPatientsPreferred modalityRoutine useInjurySubsequent strokeAngiographyScreening criteriaPhysiciansRadiologists