2025
Smoking and Postoperative Pain: A Systematic Review and Meta‐Analysis
Chow R, Lans Z, Cohen S, Lin H, Zhao J, Rajput K. Smoking and Postoperative Pain: A Systematic Review and Meta‐Analysis. Pain Practice 2025, 25: e70083. PMID: 40977634, DOI: 10.1111/papr.70083.Peer-Reviewed Original ResearchConceptsPain scoresPostoperative painOpioid requirementsPostoperative daySmoking historyAnalysis of pain scoresHigh opioid requirementsPostoperative opioid consumptionAcute postoperative painPostoperative pain scoresMeta-analysisEffects of smokingStandardized mean differenceOpioid consumptionPulmonary complicationsRate of infectionPostoperative complicationsPostoperative outcomesCardiovascular eventsPerioperative periodPainMean differenceNonsmokersSmokersStatistical significanceCirculating Tissue Specific Extracellular Vesicles for Noninvasive Monitoring of Acute Cellular Rejection in Clinical Heart Transplantation
Korutla L, Hu R, Liu Y, Romano C, Habertheuer A, Abedi P, Wang H, Molugu S, Rostami S, Naji A, Nuqali A, Beasley M, Maulion C, Hahn S, Ahmad T, Wang Z, Sen S, Vallabhajosyula P. Circulating Tissue Specific Extracellular Vesicles for Noninvasive Monitoring of Acute Cellular Rejection in Clinical Heart Transplantation. Transplantation 2025, 109: 1540-1550. PMID: 40238644, DOI: 10.1097/tp.0000000000005369.Peer-Reviewed Original ResearchModerate acute cellular rejectionAcute cellular rejectionT cellsHeart transplantationSmall extracellular vesiclesCellular rejectionAntibody-mediated rejectionEndomyocardial biopsy samplesHeart transplant patientsWilcoxon rank sum testExtracellular vesiclesClinical heart transplantationRank sum testCardiac allograftsExternal validation studyCTnT proteinTransplant patientsPostoperative dayDiagnostic accuracyBiopsy samplesSuccessful treatmentCargo of small extracellular vesiclesTransplantationPatientsDiagnostic potential
2024
Same Day Discharge after Metabolic and Bariatric Surgery in Adults 65 Years and Older: An Analysis of the 2015 to 2022 MBSAQIP
Hamid S, Graetz E, Esdaille C, Schneider E, Gibbs K. Same Day Discharge after Metabolic and Bariatric Surgery in Adults 65 Years and Older: An Analysis of the 2015 to 2022 MBSAQIP. Obesity Surgery 2024, 35: 25-32. PMID: 39636520, DOI: 10.1007/s11695-024-07611-9.Peer-Reviewed Original ResearchClavien-Dindo complicationsObesity-associated diseasesPostoperative dayBariatric surgeryPrimary sleeve gastrectomyDay dischargeInsulin-dependent diabetesSame-day dischargePOD1 dischargePostoperative morbiditySleeve gastrectomyPatient selectionSafety profileSafety of SDDPatientsSDD protocolCohort of older adultsPOD1Logistic regressionAge groupsSurgeryComplicationsMBSAQIPOlder adultsReadmissionDrug-Induced Thrombocytopenia: A Critical Condition in Hospitalized Cancer Patients
Abouelkheer Y, Ranat R, Phuong L, Boxer D, Ahasic A. Drug-Induced Thrombocytopenia: A Critical Condition in Hospitalized Cancer Patients. Blood 2024, 144: 5544-5544. DOI: 10.1182/blood-2024-211937.Peer-Reviewed Original ResearchDrug-induced thrombocytopeniaHigh risk of bleedingPlatelet factor 4Risk of bleedingPlatelet countPostoperative dayIntravenous immunoglobulinSurgical cancer patientsCancer patientsSevere thrombocytopeniaCase of severe thrombocytopeniaRecovery of platelet countsHigh riskEtiology of thrombocytopeniaBone marrow suppressionClear-cell carcinomaHeparin-Induced ThrombocytopeniaDisseminated intravascular coagulopathyImmune-mediated conditionsPostoperative day 3Postoperative day 7Consumption of plateletsPlanned surgical resectionPlatelet factor 4 antigenAdministration of dexamethasoneBilling rules / global period affect postoperative follow-up practices following total hip arthroplasty
Ratnasamy P, Oghenesume O, Joo P, Grauer J. Billing rules / global period affect postoperative follow-up practices following total hip arthroplasty. PLOS ONE 2024, 19: e0300460. PMID: 38635750, PMCID: PMC11025944, DOI: 10.1371/journal.pone.0300460.Peer-Reviewed Original ResearchConceptsFollow-up visitFollow-upTotal hip arthroplastyAdvanced practice providersPostoperative week 3Time of evaluationClinical practice patternsPostoperative visitPostoperative dayPostoperative weekFollow-up practicesPercentage of visitsHip arthroplastyPractice patternsOrthopedic surgeonsSurgeonsWeek 3Optimal outcomesWeeksVisitsPractice providersWeek-to-week variation
2023
Effects of Opioid-Limiting Legislation in the State of Ohio on Opioid Prescriptions After Shoulder Arthroscopy
Strony J, Raji Y, Trivedi N, McMellen C, Yu J, Calcei J, Voos J, Gillespie R. Effects of Opioid-Limiting Legislation in the State of Ohio on Opioid Prescriptions After Shoulder Arthroscopy. Orthopaedic Journal Of Sports Medicine 2023, 11: 23259671231202242. PMID: 38021300, PMCID: PMC10664433, DOI: 10.1177/23259671231202242.Peer-Reviewed Original ResearchOpioid prescriptionsCumulative MMEsShoulder arthroscopyOpioid dosingOpioid naïvePostoperative dayPostoperative periodRisk factorsGamma-aminobutyric acid (GABA) analogueOpioid-tolerant patientsPostoperative opioid dosageProlonged opioid useConsumption of opioidsDate of surgeryImmediate postoperative periodDay of surgeryData of patientsLevel of evidenceGABA analoguesCertain orthopedic proceduresCovariate-adjusted regression analysesFisher's exact testHigher MMEPreoperative opioidsMedical comorbiditiesDoes Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction
Walls H, Thomas E, Kain Z, Schlechter J. Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction. Journal Of Pediatric Orthopaedics 2023, 43: 511-515. PMID: 37400092, DOI: 10.1097/bpo.0000000000002466.Peer-Reviewed Original ResearchConceptsAnterior cruciate ligament reconstructionPeripheral nerve blocksCruciate ligament reconstructionVisual analog scaleNerve blockOpioid useLigament reconstructionAnalog scaleSingle-shot peripheral nerve blockAdductor canal nerve blockAverage opioid useHome opioid useHydrocodone/acetaminophenPain treatment satisfactionTreatment satisfaction scoresPostoperative pain managementACLR patientsOral acetaminophenOpioid usageUncontrolled painControl patientsNarcotic utilizationPostoperative dayOpioid analgesicsPain managementPeriarticular Injection Versus Peripheral Nerve Blockade in Bilateral Total Hip Arthroplasty
Sivco C, Townsend D, Leslie M, Li J. Periarticular Injection Versus Peripheral Nerve Blockade in Bilateral Total Hip Arthroplasty. Cureus 2023, 15: e39503. PMID: 37366446, PMCID: PMC10290567, DOI: 10.7759/cureus.39503.Peer-Reviewed Original ResearchPeripheral nerve blocksPatient pain scoresPeriarticular injectionBilateral total hip arthroplastyPain scoresPain controlPostoperative dayNerve blockPreoperative peripheral nerve blocksLateral femoral cutaneous nerve blockLeft hipLow-concentration local anestheticRight hipIntraoperative periarticular injectionPostoperative pain controlTransmuscular quadratus lumborumPeripheral nerve blockadeTotal hip arthroplastyImprove surgical outcomesAnalgesic modalitiesHip arthroplastyLiposomal bupivacaineSurgical outcomesNerve blockadeBilateral hip replacementEffects of Opioid-Limiting Legislation and Increased Provider Awareness on Postoperative Opioid Use and Complications After Hip Arthroscopy
Strony J, Raji Y, Ina J, Yu J, Megerian M, McCollum S, Mather R, Nho S, Salata M. Effects of Opioid-Limiting Legislation and Increased Provider Awareness on Postoperative Opioid Use and Complications After Hip Arthroscopy. Orthopaedic Journal Of Sports Medicine 2023, 11: 23259671231162340. PMID: 37152553, PMCID: PMC10159253, DOI: 10.1177/23259671231162340.Peer-Reviewed Original ResearchPreoperative opioid useCumulative MMEsHip arthroscopyOpioid useHospital readmissionRisk factorsSignificant independent risk factorsSignificant between-group differencesRx Reporting SystemPostoperative opioid useIndependent risk factorEmergency department visitsSignificant risk factorsLevel of evidencePatients' medical recordsBetween-group differencesCertain orthopedic proceduresOpioid dosingPOST cohortCohort studyED utilizationPostoperative dayDepartment visitsED encountersPRE group
2022
Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty
Del Toro-Pagán NM, Dai F, Banack T, Berlin J, Makadia SA, Rubin LE, Zhou B, Huynh P, Li J. Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty. Journal Of Pain Research 2022, 15: 2537-2546. PMID: 36061486, PMCID: PMC9432382, DOI: 10.2147/jpr.s378243.Peer-Reviewed Original ResearchWhite blood cell countTotal knee arthroplastyActive pain scoresCumulative opioid consumptionOpioid consumptionPostoperative opioid consumptionMethylprednisolone acetateMPA groupPain scoresPostoperative dayNerve blockDEX groupKnee arthroplastySingle-injection nerve blocksConsecutive TKA patientsDaily opioid consumptionPosterior knee (IPACK) blockLocal anesthetic adjuvantBlood cell countLength of stayHigher restKnee blockHospital stayTKA patientsSecondary outcomes
2021
Risk Prediction Models for Postoperative Decompensation and Infection in Patients With Cirrhosis: A Veterans Affairs Cohort Study
Mahmud N, Fricker Z, Lewis JD, Taddei TH, Goldberg DS, Kaplan DE. Risk Prediction Models for Postoperative Decompensation and Infection in Patients With Cirrhosis: A Veterans Affairs Cohort Study. Clinical Gastroenterology And Hepatology 2021, 20: e1121-e1134. PMID: 34246794, PMCID: PMC8741885, DOI: 10.1016/j.cgh.2021.06.050.Peer-Reviewed Original ResearchConceptsLiver diseasePostoperative decompensationPostoperative mortalityPostoperative infectionRisk scoreAlcohol-related liver diseaseEnd-stage liver diseaseMayo risk scoreSurgical risk scoresData of patientsMultivariable logistic regressionVeterans Health AdministrationRange of surgeryRisk prediction modelCirrhosis decompensationPugh scoreChild-TurcottePostoperative complicationsCohort studyPostoperative dayRetrospective studyStratify patientsVeteran outcomesDecompensationExcellent calibrationDo Patient Expectations of Discharge Affect Length of Stay after Deep Inferior Epigastric Perforator Flap for Breast Reconstruction?
Bamba R, Wiebe J, Ingersol C, Dawson S, Sinha M, Cohen A, Hartman B, Lester M, Hassanein A. Do Patient Expectations of Discharge Affect Length of Stay after Deep Inferior Epigastric Perforator Flap for Breast Reconstruction? Journal Of Reconstructive Microsurgery 2021, 38: 34-40. PMID: 33853122, DOI: 10.1055/s-0041-1727201.Peer-Reviewed Original ResearchConceptsDeep inferior epigastric artery perforatorDeep inferior epigastric artery perforator flapBody mass indexLength of stayPostoperative dayBreast reconstructionERAS protocolGroup IIGroup IBilateral DIEPsPatient expectationsDeep inferior epigastric perforator flapPostoperative days 3 to 4Inferior epigastric artery perforatorDischarged postoperative dayGroup II patientsAverage body mass indexGroup I patientsMethod of breast reconstructionPostoperative days 4 to 5Retrospective chart reviewPostoperative day 3Primary outcome variableEffect of patient expectationsDIEP patients
2019
Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities
Ottesen TD, Yurter A, Shultz BN, Galivanche AR, Zogg CK, Bovonratwet P, Rubin LE, Grauer JN. Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities. JAAOS Global Research And Reviews 2019, 3: e086. PMID: 31592508, PMCID: PMC6754213, DOI: 10.5435/jaaosglobal-d-19-00086.Peer-Reviewed Original ResearchHip fracture surgeryDialysis-dependent patientsPerioperative adverse eventsAdverse eventsFracture surgeryDialysis dependenceDialysis patientsHip fractureGreater oddsNational Surgical Quality Improvement Program databaseGeriatric hip fracture surgeryRisk-adjusted logistic regressionQuality Improvement Program databaseInstitutional cohort studyNational patient populationPreoperative dialysis dependenceMinor adverse eventsHip fracture careImprovement Program databaseMajor adverse eventsDemographic factorsUnplanned readmissionCohort studyPerioperative periodPostoperative dayCardiac MRI-guided interventional occlusion of ventricular septal rupture in a patient with cobalt alloy stent.
Zhong W, Liu Z, Fan W, Hameed I, Salemi A, Butera G, Zucker EJ, Huang C, Zhong Z. Cardiac MRI-guided interventional occlusion of ventricular septal rupture in a patient with cobalt alloy stent. Annals Of Translational Medicine 2019, 7: 395. PMID: 31555709, PMCID: PMC6736796, DOI: 10.21037/atm.2019.07.55.Peer-Reviewed Original ResearchCardiac magnetic resonance imagingVentricular septal ruptureMagnetic resonance imagingSeptal ruptureMid-left anteriorInterventional occlusionChest painSubtotal occlusionPostoperative dayRight shuntBalloon dilationCoronary angiographyNormal cardiac tissueVentricular aneurysmInterventional therapyCardiac apexOcclusion siteResonance imagingMembranous septumPatientsCardiac tissueShuntOcclusionAccurate assessmentSuperoinferior axes
2018
Incidence and considerations of 90-day readmissions following posterior lumbar fusion
Cui JJ, Gala RJ, Ondeck NT, McLynn RP, Bovonratwet P, Shultz B, Grauer JN. Incidence and considerations of 90-day readmissions following posterior lumbar fusion. The Spine Journal 2018, 19: 631-636. PMID: 30219360, DOI: 10.1016/j.spinee.2018.09.004.Peer-Reviewed Original ResearchConceptsPosterior lumbar fusionDays of dischargeReadmission ratesBaseline readmission ratesHuman Investigation CommitteeAdmission ratesDay readmissionLumbar fusionUtilization Project Nationwide Readmissions DatabaseAverage daily admission rateBaseline admission rateBundled payment plansNationwide Readmissions DatabaseHospital admission dataAverage admission rateDaily admission ratesCalendar yearCurrent quality metricsPLF patientsPatient demographicsPostoperative dayRetrospective studyPatient counselingPatient outcomesSpine surgeryTiming of Adverse Events Following Geriatric Hip Fracture Surgery: A Study of 19,873 Patients in the American College of Surgeons National Surgical Quality Improvement Program.
Bohl DD, Samuel AM, Webb ML, Lukasiewicz AM, Ondeck NT, Basques BA, Anandasivam NS, Grauer JN. Timing of Adverse Events Following Geriatric Hip Fracture Surgery: A Study of 19,873 Patients in the American College of Surgeons National Surgical Quality Improvement Program. The American Journal Of Orthopedics 2018, 47 PMID: 30296324, DOI: 10.12788/ajo.2018.0080.Peer-Reviewed Original ResearchConceptsSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramGeriatric hip fracture surgerySurgical Quality Improvement ProgramHip fracture surgeryAdverse eventsPostoperative day 30Quality Improvement ProgramFracture surgeryAmerican CollegeDay 30Urinary tract infections 7Median postoperative dayProspective surgical registryPostoperative adverse eventsSpecific adverse eventsInfection 7Mortality 11Pneumonia 4Postoperative dayHip fractureCardiac arrestClinical surveillancePatient counselingMyocardial infarctionDecreased Surgical Site Infection Rate in Hysterectomy
Andiman SE, Xu X, Boyce JM, Ludwig EM, Rillstone HRW, Desai VB, Fan LL. Decreased Surgical Site Infection Rate in Hysterectomy. Obstetrics And Gynecology 2018, 131: 991-999. PMID: 29742666, DOI: 10.1097/aog.0000000000002594.Peer-Reviewed Original ResearchConceptsSurgical site infection prevention bundleSurgical site infection rateInfection prevention bundleSurgical site infectionPrevention bundleSite infectionInfection rateHospital stayStudy periodPostoperative readmission rateProportion of patientsRate of readmissionMultivariable regression analysisImplementation periodQuality improvement studyPerioperative normothermiaClinical characteristicsPostoperative dayReadmission ratesAntibiotic dosingRetrospective analysisSustained reductionSurgical preparationHysterectomyPatients
2017
What Is the Timing of General Health Adverse Events That Occur After Total Joint Arthroplasty?
Bohl DD, Ondeck NT, Basques BA, Levine BR, Grauer JN. What Is the Timing of General Health Adverse Events That Occur After Total Joint Arthroplasty? Clinical Orthopaedics And Related Research® 2017, 475: 2952-2959. PMID: 28054326, PMCID: PMC5670043, DOI: 10.1007/s11999-016-5224-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overArthroplasty, Replacement, HipArthroplasty, Replacement, KneeData MiningDatabases, FactualHumansLength of StayMiddle AgedMultivariate AnalysisPatient DischargePostoperative ComplicationsProcess Assessment, Health CareProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsTotal joint arthroplastyAdverse eventsDays of diagnosisDeep vein thrombosisPulmonary embolismPostoperative dayVein thrombosisMyocardial infarctionJoint arthroplastySurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramMultivariate Cox proportional hazardsSurgical Quality Improvement ProgramMedian postoperative dayPulmonary embolism 3Postoperative adverse eventsSurgical site infectionMyocardial infarction 3Different adverse eventsRetrospective database analysisLife-threatening findingsCertain adverse eventsCox proportional hazardsSuch adverse eventsQuality Improvement ProgramLaparoscopic gastroesophageal dissociation in neurologically impaired children with gastroesophageal reflux disease
DeAntonio J, Parrish D, Rosati S, Oiticica C, Lanning D. Laparoscopic gastroesophageal dissociation in neurologically impaired children with gastroesophageal reflux disease. Journal Of Pediatric Surgery 2017, 53: 30-35. PMID: 29103790, DOI: 10.1016/j.jpedsurg.2017.10.010.Peer-Reviewed Original ResearchSevere gastroesophageal reflux diseaseGastroesophageal reflux diseaseNeurologically impaired childrenQuality of lifeImprove quality of lifeReflux diseaseHealthcare visitsRetrospective case series reviewNeurologically impaired patientsEstimated blood lossCase series reviewCohort of patientsGram negative sepsisGroup of patientsDuration of operationLevel IV evidenceLength of stayImpaired patientsBlood lossRetrospective reviewNegative sepsisImpaired childrenPediatric patientsPostoperative dayCase seriesComparison of Perioperative Adverse Event Rates After Total Knee Arthroplasty in Patients With Diabetes: Insulin Dependence Makes a Difference
Webb ML, Golinvaux NS, Ibe IK, Bovonratwet P, Ellman MS, Grauer JN. Comparison of Perioperative Adverse Event Rates After Total Knee Arthroplasty in Patients With Diabetes: Insulin Dependence Makes a Difference. The Journal Of Arthroplasty 2017, 32: 2947-2951. PMID: 28559194, DOI: 10.1016/j.arth.2017.04.032.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedArthroplasty, Replacement, KneeComorbidityDatabases, FactualDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleHumansInsulinMaleMiddle AgedOrthopedic ProceduresPostoperative ComplicationsPrevalenceQuality ImprovementRetrospective StudiesRisk FactorsTreatment OutcomeUnited StatesYoung AdultConceptsTotal knee arthroplastyInsulin-dependent DMDiabetes mellitusAdverse eventsGreater riskKnee arthroplastySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databasePerioperative adverse event ratesQuality Improvement Program databaseInsulin-dependent diabetes mellitusPerioperative adverse outcomesRetrospective cohort studyImprovement Program databasePerioperative adverse eventsAdverse event ratesDependent diabetes mellitusPreoperative risk stratificationEffective treatment optionMultivariate Poisson regressionMultiple adverse eventsCohort studyInsulin dependencePostoperative daySurgical complications
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