2020
Cardiovascular Imaging of Biology and Emotion
Meadows JL, Shah S, Burg MM, Pfau S, Soufer R. Cardiovascular Imaging of Biology and Emotion. Circulation Cardiovascular Imaging 2020, 13: e011054. PMID: 32762255, PMCID: PMC9261020, DOI: 10.1161/circimaging.120.011054.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMental stressEpicardial coronary artery diseaseCoronary artery diseaseExercise-induced changesMicrovascular dysfunctionArtery diseaseObstructive diseaseClinical manifestationsVascular responsesCentral activationCardiovascular healthPathophysiologic changesCardiovascular responsesMyocardial ischemiaPeripheral vasculatureTreatment targetsVascular pathophysiologyPsychosocial determinantsCardiovascular imagingPsychosocial experiencesImplementation studyMS testingTriggers activationCardiovascular biologyDisease
2018
Deep Learning Analysis of Upright-Supine High-Efficiency SPECT Myocardial Perfusion Imaging for Prediction of Obstructive Coronary Artery Disease: A Multicenter Study
Betancur J, Hu LH, Commandeur F, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Otaki Y, Liang JX, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Deep Learning Analysis of Upright-Supine High-Efficiency SPECT Myocardial Perfusion Imaging for Prediction of Obstructive Coronary Artery Disease: A Multicenter Study. Journal Of Nuclear Medicine 2018, 60: 664-670. PMID: 30262516, PMCID: PMC6495237, DOI: 10.2967/jnumed.118.213538.Peer-Reviewed Original ResearchConceptsTotal perfusion deficitMyocardial perfusion imagingSPECT myocardial perfusion imagingCoronary artery diseaseObstructive diseaseClinical readsArtery diseaseCoronary arteryPerfusion imagingTc-sestamibi myocardial perfusion imagingObstructive coronary artery diseaseLeft main coronary arteryStress myocardial perfusion imagingStress total perfusion deficitMain coronary arteryMajor coronary arteriesLeft ventricular myocardiumHypoperfusion severityRadiotracer countsMulticenter studyPerfusion deficitsNormal limitsVessel sensitivityPatient sensitivityPatientsPresentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study
Safdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.Peer-Reviewed Original ResearchConceptsMI-CAD patientsNonobstructive coronary arteriesMI-CADYounger patientsClinical profileCoronary arteryMyocardial infarctionTraditional cardiac risk factorsAcute myocardial infarction patientsCardiac risk factorsGestational diabetes mellitusMyocardial infarction patientsTimes higher oddsMINOCA patientsSAQ qualityVIRGO StudyClinical characteristicsHypercoaguable stateDiabetes mellitusObstructive diseaseClinical outcomesInfarction patientsRisk factorsMINOCAPsychosocial statusDeep Learning for Prediction of Obstructive Disease From Fast Myocardial Perfusion SPECT A Multicenter Study
Betancur J, Commandeur F, Motlagh M, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Deep Learning for Prediction of Obstructive Disease From Fast Myocardial Perfusion SPECT A Multicenter Study. JACC Cardiovascular Imaging 2018, 11: 1654-1663. PMID: 29550305, PMCID: PMC6135711, DOI: 10.1016/j.jcmg.2018.01.020.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCoronary CirculationCoronary StenosisDeep LearningFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedMyocardial Perfusion ImagingOrganophosphorus CompoundsOrganotechnetium CompoundsPredictive Value of TestsRadiopharmaceuticalsRegistriesTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonConceptsTotal perfusion deficitMyocardial perfusion imagingCoronary artery diseaseObstructive diseaseArtery diseaseVessel coronary artery diseaseTomography myocardial perfusion imagingTetrofosmin myocardial perfusion imagingLarge multicenter populationStress total perfusion deficitReceiver-operating characteristic curveInvasive coronary angiographyLeft ventricular myocardiumSingle photon emissionMyocardial perfusion SPECTMonths of MPIMulticenter populationObstructive stenosisCoronary angiographyMulticenter studyCoronary arteryPerfusion deficitsNormal limitsVessel sensitivityCurrent clinical methods
2016
Longitudinal analysis of the lung microbiota of cynomolgous macaques during long-term SHIV infection
Morris A, Paulson J, Talukder H, Tipton L, Kling H, Cui L, Fitch A, Pop M, Norris K, Ghedin E. Longitudinal analysis of the lung microbiota of cynomolgous macaques during long-term SHIV infection. Microbiome 2016, 4: 38. PMID: 27391224, PMCID: PMC4939015, DOI: 10.1186/s40168-016-0183-0.Peer-Reviewed Original ResearchConceptsDevelopment of obstructive lung diseaseObstructive lung diseaseNon-human primate modelLung microbiomeSHIV infectionLung microbiotaRibosomal RNALung diseasePrimate modelNon-obstructive groupSHIV-infected animalsResponse to immunosuppressionBronchoalveolar lavage fluid samplesCynomolgous macaquesDevelopment of obstructive diseaseLavage fluid samplesMultiple other speciesSIV-HIVOral anaerobesOral bacteriaTropheryma whippleiObstructive diseaseCommunity compositionBacterial communitiesDisease onsetCharacteristics of Patients Undergoing Cardiac Catheterization Before Noncardiac Surgery: A Report From the National Cardiovascular Data Registry CathPCI Registry
Schulman-Marcus J, Feldman D, Rao S, Prasad A, McCoy L, Garratt K, Kim L, Minutello R, Wong S, Vora A, Singh H, Wojdyla D, Mohsen A, Bergman G, Swaminathan R. Characteristics of Patients Undergoing Cardiac Catheterization Before Noncardiac Surgery: A Report From the National Cardiovascular Data Registry CathPCI Registry. JAMA Internal Medicine 2016, 176: 611. PMID: 27018942, DOI: 10.1001/jamainternmed.2016.0259.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexCardiac CatheterizationCohort StudiesCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseDiabetes ComplicationsDrug-Eluting StentsFemaleHumansMaleMiddle AgedObesityOverweightPercutaneous Coronary InterventionRegistriesRetrospective StudiesRisk FactorsSurvival AnalysisTreatment OutcomeUnited StatesConceptsPercutaneous coronary interventionNoncardiac surgeryCardiac catheterizationAngiographic findingsDiagnostic catheterizationObstructive diseaseObstructive coronary artery diseaseProximal left anterior descending arteryLeft anterior descending arteryClinically stable patientsNoninvasive stress testingCohort of patientsNoninvasive test resultsContemporary US cohortAcute coronary syndromeAnterior descending arteryCoronary artery diseaseRandomized clinical trialsLeft main arteryEvidence-based guidelinesAsymptomatic patientsMedian agePercutaneous coronary intervention dataAntianginal medicationsCoronary angiography
2014
Critical evaluation of stents in the peripheral arterial disease of the superficial femoral artery – focus on the paclitaxel eluting stent
Litsky J, Chanda A, Stilp E, Lansky A, Mena C. Critical evaluation of stents in the peripheral arterial disease of the superficial femoral artery – focus on the paclitaxel eluting stent. Medical Devices Evidence And Research 2014, 7: 149-156. PMID: 24920940, PMCID: PMC4045256, DOI: 10.2147/mder.s45472.Peer-Reviewed Original ResearchSuperficial femoral arteryPeripheral arterial diseaseArterial diseaseSymptomatic peripheral arterial diseasePercutaneous transluminal balloon angioplastyPreferred initial therapyTransluminal balloon angioplastySelf-expanding nitinol stentsInitial therapyObstructive lesionsSFA diseaseEndovascular managementObstructive diseaseEndovascular treatmentAdequate therapyBalloon angioplastySFA stenosisFemoral arteryDurable resultsClinical practiceLong occlusionsDiseaseNitinol stentsStentsBiomechanical forces
2009
Impact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement
Tsujita K, Maehara A, Mintz GS, Doi H, Kubo T, Castellanos C, Liu J, Yang J, Oviedo C, Franklin-Bond T, Sugirtharaj DD, Dangas GD, Lansky AJ, Stone GW, Moses JW, Leon MB, Mehran R. Impact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement. The American Journal Of Cardiology 2009, 103: 1344-1348. PMID: 19427426, DOI: 10.1016/j.amjcard.2009.01.340.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationCoronary stent placementStent placementMyocardial bridgeArtery lesionsObstructive lesionsClinical outcomesStent groupTarget lesion revascularization rateStent group patientsTarget vessel revascularizationComposite end pointCoronary artery lesionsMinimum stent areaGroup patientsRevascularization ratesConsecutive patientsLeft anteriorObstructive diseaseSystolic compressionCoronary arterySignificant plaqueStent areaStent restenosisIntravascular ultrasound
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