2025
Neuroendocrine responses and coupling to laboratory-induced stress in problem gambling and heavy smoking
Wemm S, Holzhauer C, Harrison L, Milivojevic V, Fogelman N, Cao Z, Wulfert E. Neuroendocrine responses and coupling to laboratory-induced stress in problem gambling and heavy smoking. Psychoneuroendocrinology 2025, 177: 107469. PMID: 40250213, PMCID: PMC12131328, DOI: 10.1016/j.psyneuen.2025.107469.Peer-Reviewed Original ResearchConceptsTrier Social Stress TestHypothalamic-pituitary-adrenal axisAxis responseProblem gamblingPathophysiology of addictive disordersHPA axis responseSocial Stress TestHypothalamic-pituitary-gonadal axisHealthy control participantsLaboratory-induced stressStress-related changesStress hormone cortisolHypothalamic-pituitary-gonadal axis hormonesAddictive disordersAddiction mechanismsLaboratory stressorSubstance addictionControl participantsNeuroactive steroidsNeuroendocrine responsesAttenuated cortisolPsychological featuresProblem gamblersHormone cortisolGambling
2019
Food craving, cortisol and ghrelin responses in modeling highly palatable snack intake in the laboratory
Sinha R, Gu P, Hart R, Guarnaccia JB. Food craving, cortisol and ghrelin responses in modeling highly palatable snack intake in the laboratory. Physiology & Behavior 2019, 208: 112563. PMID: 31145919, PMCID: PMC6620125, DOI: 10.1016/j.physbeh.2019.112563.Peer-Reviewed Original ResearchConceptsFood cuesHP foodsCue exposureFood cravingsFood motivationFood cue exposureOverweight/obese rangeImagery exposureImagery conditionCue environmentSnack testBiobehavioral processesBody mass indexPalatable foodNeutral conditionsCuesNeuroendocrine responsesSnack intakeGroup effectsOB conditionsCravingTest dayAnxietyWeight gainCortisol response
2017
Cardiovascular System
Akhtar S, Ebert T. Cardiovascular System. 2017, 161-178. DOI: 10.1007/978-3-319-66878-9_11.ChaptersCardiovascular diseaseCardiovascular systemBest possible patient outcomesFrequency of dysrhythmiasPerioperative stress responseCoronary blood flowValvular heart diseaseAge-related disease processesPossible patient outcomesCardiac conduction systemAge-related changesElderly patientsCardiovascular reserveMyocardial dysfunctionDiastolic fillingCardiac functionHeart diseasePatient outcomesPathophysiological principlesCardiovascular stressHeart rateNeuroendocrine responsesAutonomic regulationBlood flowDisease process
2000
Modelling a loss event: effect of imagined bereavement on the hypothalamic–pituitary–adrenal axis
McCLEERY J, BHAGWAGAR Z, SMITH K, GOODWIN G, COWEN P. Modelling a loss event: effect of imagined bereavement on the hypothalamic–pituitary–adrenal axis. Psychological Medicine 2000, 30: 219-223. PMID: 10722192, DOI: 10.1017/s0033291799001361.Peer-Reviewed Original ResearchConceptsNegative mood induction procedureNegative mood inductionMood induction procedureMood inductionRelevant psychosocial stressorsIndividual differencesCortisol responseSalivary cortisol responseTransient moodPsychological stateInduction procedureAcute cortisol responsePsychosocial stressorsMood disorders researchDisorder researchCortisol outputStressorsBereavementNeuroendocrine responsesMoodAdrenal axisDepressive illnessHealthy volunteersMusicImportant mediator
1995
Morphological Evidence for a Galanin‐Opiate Interaction in the Rat Mediobasal Hypothalamus
Horvath T, Kalra S, Naftolin F, Leranth C. Morphological Evidence for a Galanin‐Opiate Interaction in the Rat Mediobasal Hypothalamus. Journal Of Neuroendocrinology 1995, 7: 579-588. PMID: 8704731, DOI: 10.1111/j.1365-2826.1995.tb00795.x.Peer-Reviewed Original ResearchConceptsBeta-endorphin cellsBeta-endorphin neuronsArcuate nucleusBeta-endorphinMediobasal hypothalamusImmunoreactive profilesPituitary hormone secretionBeta-endorphin releaseDay survival periodRat mediobasal hypothalamusDiaminobenzidine reactionGalanin fibersHalász knifeImmunoreactive neuronsHormone secretionContralateral sideFemale ratsHypothalamic galaninProlactin secretionAdditional ratsElectron microscopic examinationPituitary hormonesSurvival periodNeuroendocrine responsesGalanin
1992
Dose-response relationship for oral idazoxan effects in healthy human subjects: comparison with oral yohimbine
Krystal J, McDougle C, Woods S, Price L, Heninger G, Charney D. Dose-response relationship for oral idazoxan effects in healthy human subjects: comparison with oral yohimbine. Psychopharmacology 1992, 108: 313-319. PMID: 1355923, DOI: 10.1007/bf02245117.Peer-Reviewed Original ResearchConceptsHealthy subjectsDiastolic blood pressureΑ2-adrenergic receptorsSymptom scale scoresHealthy human subjectsDose-response relationshipIdazoxan doseBlood pressureOral yohimbineNorepinephrine metabolitePlasma levelsMedication effectsOral administrationPlasma MHPGPhysiologic indicesNeuroendocrine responsesΑ2 antagonistAdrenergic receptorsCortisol levelsScale scorePlasma cortisolYohimbineIdazoxanAnxiety statesReceptor specificity
1991
Effects of ritanserin on the behavioral, neuroendocrine, and cardiovascular responses to meta-chlorophenylpiperazine in healthy human subjects
Seibyl J, Krystal J, Price L, Woods S, D'Amico C, Heninger G, Charney D. Effects of ritanserin on the behavioral, neuroendocrine, and cardiovascular responses to meta-chlorophenylpiperazine in healthy human subjects. Psychiatry Research 1991, 38: 227-236. PMID: 1754635, DOI: 10.1016/0165-1781(91)90013-f.Peer-Reviewed Original ResearchConceptsGrowth hormone responseEffects of ritanserinHealthy male subjectsHealthy human subjectsSelf-rated anxietyMCPP infusionAgonist mCPPCardiovascular effectsHT2 receptorCardiovascular responsesNeuroendocrine responsesRitanserinHormone responseMale subjectsCortisol elevationBehavioral responsesHuman subjectsMCPPSubjectsResponsePlaceboPremedicationChlorophenylpiperazineInfusionAntagonist
1981
Plasma free MHPG and neuroendocrine responses to challenge doses of clonidine in Tourette's Syndrome: Preliminary report
Young J, Cohen D, Hattox S, Kavanagh M, Anderson G, Shaywitz B, Maas J. Plasma free MHPG and neuroendocrine responses to challenge doses of clonidine in Tourette's Syndrome: Preliminary report. Life Sciences 1981, 29: 1467-1475. PMID: 6946271, DOI: 10.1016/0024-3205(81)90012-6.Peer-Reviewed Original ResearchConceptsFree MHPGPlasma free MHPGTourette syndromeChallenge doseNeuroendocrine responsesDoses of clonidineSingle oral dosesClonidine administrationResponsive patientsGH responseOral dosesMaintenance treatmentThyroxine indexClonidineTS patientsPatientsMHPGSyndromeT patientsNeuropsychiatric patientsPilot studyPreliminary reportMetabolic responseFurther investigationDose
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