2025
The Moderating Role of Genetic and Environmental Risk Factors for Schizophrenia on the Relationship between Autistic Traits and Psychosis Expression in the General Population
Dogan M, Prachason T, Lin B, Pries L, Arias-Magnasco A, Bortoletto R, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, van Os J, Rutten B, Brondino N, Colizzi M, Luykx J, Fusar-Poli L, Guloksuz S. The Moderating Role of Genetic and Environmental Risk Factors for Schizophrenia on the Relationship between Autistic Traits and Psychosis Expression in the General Population. Schizophrenia Bulletin Open 2025, 6: sgaf005. PMID: 40123716, PMCID: PMC11926675, DOI: 10.1093/schizbullopen/sgaf005.Peer-Reviewed Original ResearchPsychotic experiencesNegative life eventsAutistic traitsLife eventsCommunity Assessment of Psychic ExperiencesAssociated with psychotic experiencesAutism Spectrum QuotientModerating RolePsychosis expressionInteraction effectsPolygenic risk scoresRisk factorsEmotional neglectPsychic ExperiencesPhysical neglectModeration analysisCT subtypesAutism spectrumBonferroni correctionEmotional abuseGenetic overlapMultilevel linear regression modelsTrauma screeningSexual abusePhysical abuseHeterogeneity in Developmental Trajectories of Internalizing and Externalizing Symptomatology: Associations with Risk and Protective Factors
Brieant A, Cai T, Ip K, Holt-Gosselin B, Gee D. Heterogeneity in Developmental Trajectories of Internalizing and Externalizing Symptomatology: Associations with Risk and Protective Factors. Child Psychiatry & Human Development 2025, 1-12. PMID: 39786680, DOI: 10.1007/s10578-024-01804-0.Peer-Reviewed Original ResearchAdolescent Brain Cognitive DevelopmentHigh-decreasing classModerate-increasing classTrajectories of psychopathologyNegative life eventsLow-stable classSample of youthLow-decreasing classGrowth mixture modelingProtective factorsExternalizing symptomatologyPsychopathological trajectoriesExternalizing symptomsProportion of youthLife eventsDevelopmental trajectoriesPsychopathologyCognitive developmentExternalizing trajectoriesTrajectory classesParental acceptanceLatent classesDevelopmental patternsInternational trajectoriesCo-development
2024
Negative Life Events and Emotional Symptoms From Ages 2 to 30 Years
Copeland W, Keen R, Tong G, Shanahan L. Negative Life Events and Emotional Symptoms From Ages 2 to 30 Years. JAMA Network Open 2024, 7: e2429448. PMID: 39207754, PMCID: PMC11362870, DOI: 10.1001/jamanetworkopen.2024.29448.Peer-Reviewed Original ResearchConceptsCross-sectional analysisEmotional symptomsNegative life eventsAssociated with emotional symptomsLife eventsYoung adulthoodAssociated with increased mental health symptomsCohort study analyzed dataStressful eventsTraumatic eventsMental health symptomsCross-sectional associationsLongitudinal analysisAged 2Years of follow-upStudy analyzed dataDevelopmental periodIndividuals aged 2Lifetime traumatic eventsHealth symptomsMain OutcomesLate adolescenceEmotional functioningCohort studyPrimary outcomeS18 Neural Correlates of Controllable Negative Life Events and Their Relationships With Cannabis and Alcohol Use Initiation
Zhao Y, Potenza M, Tapert S, Paulus M. S18 Neural Correlates of Controllable Negative Life Events and Their Relationships With Cannabis and Alcohol Use Initiation. Drug And Alcohol Dependence 2024, 260: 110129. DOI: 10.1016/j.drugalcdep.2023.110129.Peer-Reviewed Original Research
2023
Neural correlates of negative life events and their relationships with alcohol and cannabis use initiation
Zhao Y, Potenza M, Tapert S, Paulus M. Neural correlates of negative life events and their relationships with alcohol and cannabis use initiation. Dialogues In Clinical Neuroscience 2023, 25: 112-121. PMID: 37916739, PMCID: PMC10623894, DOI: 10.1080/19585969.2023.2252437.Peer-Reviewed Original ResearchConceptsNegative life eventsCannabis initiationGreater cortical thicknessCaudate gray matter volumeGray matter volumeDose-response relationshipOdds of alcoholLife eventsInitiation of alcoholSubstance Use InitiationCortical thicknessSubstance-naïveSuperior temporal sulcusNeural pathwaysCannabis useBrain structuresAlcohol useUse initiationAlcohol initiationSubstance use trajectoriesPoor academic performanceTemporal sulcusNeural mechanismsCannabisLinear regression modelsGene–environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding
Klingenberg B, Guloksuz S, Pries L, Cinar O, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Lin B, Luykx J, van Os J, Rutten B. Gene–environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding. Personality Neuroscience 2023, 6: e5. PMID: 38107775, PMCID: PMC10725776, DOI: 10.1017/pen.2023.2.Peer-Reviewed Original ResearchChildhood adversityParental bondingLife eventsPositive life eventsNegative life eventsGene-environment correlationGenetic vulnerabilityEysenck Personality QuestionnaireParental bonding stylesExpression of neuroticismPaternal bondingNeuroticismPersonality QuestionnaireAdversityMultilevel mixed-effects modelsMaternal bondingVeteran Experiences With Suicide Ideation, Suicide Attempt, and Social Support in Safety Planning Within the Department of Veterans Affairs
Matthieu M, Morissette S, Clafferty S, Degutis L, Oliver C, Adkins D, DeBeer B. Veteran Experiences With Suicide Ideation, Suicide Attempt, and Social Support in Safety Planning Within the Department of Veterans Affairs. Military Medicine 2023, 188: e3289-e3294. PMID: 37201198, DOI: 10.1093/milmed/usad144.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationSuicide attemptsSuicidal ideationVeterans Affairs Health Care SystemSuicide prevention interventionsHealth care facilitiesWarning signsHealth care systemSafety planningSafety planPrevention interventionsRisk veteransCare facilitiesHealth AdministrationDrug useVeterans AffairsSuicide preventionCare systemNegative life eventsPersonal coping strategiesVeteransIdeationSuicide ideationLife eventsSocial support
2022
Stressful Life Events and Chronic Fatigue Among Chinese Government Employees: A Population-Based Cohort Study
Qiu D, He J, Li Y, Li R, Ouyang F, Li L, Luo D, Xiao S. Stressful Life Events and Chronic Fatigue Among Chinese Government Employees: A Population-Based Cohort Study. Frontiers In Public Health 2022, 10: 890604. PMID: 35875038, PMCID: PMC9300904, DOI: 10.3389/fpubh.2022.890604.Peer-Reviewed Original ResearchConceptsAssociated with self-reported fatigueSelf-reported fatigueStressful life eventsChinese government employeesNegative stressful life eventsLife Events ScaleLife eventsHealth behavior related factorsPopulation-based cohort studyChronic fatigueAssociated with fatigueBehavior related factorsCumulative life eventsBinary logistic regression analysisParticipants' healthGovernment employeesFollow-upLogistic regression analysisSociodemographic factorsAssociated with lower incidenceProspective associationsEffective interventionsNegative life eventsCohort studyPositive stressful life eventsThe Association Between Life Events and Incidence of Hypertension Among Government Employees in China: A Prospective Cohort Study
Ouyang F, He J, Cheng X, Qiu D, Li L, Bangura J, Duan Y, Luo D, Xiao S. The Association Between Life Events and Incidence of Hypertension Among Government Employees in China: A Prospective Cohort Study. Frontiers In Psychology 2022, 13: 822610. PMID: 35707654, PMCID: PMC9190203, DOI: 10.3389/fpsyg.2022.822610.Peer-Reviewed Original ResearchIncidence rate ratiosRisk of hypertensionProspective cohort studyIncreased risk of HTNLife eventsHypertension riskHypertension incidenceNegative life eventsCohort studyPositive life eventsConfidence intervalsHypertension incidence rateIncreased riskRisk factorsPoisson regression modelsWork-related life eventsGlobal public health concernPublic health concernIncidence of hypertensionSociodemographic characteristicsGovernment employeesHypertension diagnosisRate ratiosIncidence ratePrevention strategies
2021
Associations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study
Brieant AE, Sisk LM, Gee DG. Associations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study. Developmental Cognitive Neuroscience 2021, 52: 101022. PMID: 34710799, PMCID: PMC8556598, DOI: 10.1016/j.dcn.2021.101022.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityNegative life eventsLife eventsInternalizing symptomsAdversity exposureCortico-limbic connectivityParental acceptanceAdolescent Brain Cognitive Development (ABCD) studyLongitudinal structural equation modelLower internalizing symptomsCognitive Development StudyContext of adversityIndirect effectsSample of youthStressful childhood experiencesCortico-limbic networkStructural equation modelLater psychopathologyNeurobiological maturationInternalizing problemsABCD studyFunctional connectivityChildhood experiencesPotential protective effectPsychopathologyStressful life events and poor sleep quality: a cross-sectional survey in the Chinese governmental employees
Li Y, Qiu D, Hu C, Ouyang F, He J, Zang D, Luo D, Xiao S. Stressful life events and poor sleep quality: a cross-sectional survey in the Chinese governmental employees. Sleep Medicine 2021, 85: 123-130. PMID: 34325381, DOI: 10.1016/j.sleep.2021.06.030.Peer-Reviewed Original ResearchConceptsStressful life eventsAssociated with poor sleep qualityNegative life eventsLife eventsPoor sleep qualitySleep qualityGovernmental employeesCumulative life eventsPositive life eventsSpecific life eventsLikelihood of poor sleep qualityOdds ratioConfidence intervalsAssociated with sleep qualityCross-sectional surveyAssociated with 3 timesLogistic regression modelsEmployeesCross-sectional dataWork stressSpouse's parentsJob dissatisfactionLifestyle changesChronic diseasesCohort study
2019
Interactions between chemicals and non-chemical stressors: The modifying effect of life events on the association between triclocarban, phenols and parabens with gestational length in a Puerto Rican cohort
Aker A, McConnell R, Loch-Caruso R, Park S, Mukherjee B, Rosario Z, Vélez-Vega C, Huerta-Montanez G, Alshawabkeh A, Cordero J, Meeker J. Interactions between chemicals and non-chemical stressors: The modifying effect of life events on the association between triclocarban, phenols and parabens with gestational length in a Puerto Rican cohort. The Science Of The Total Environment 2019, 708: 134719. PMID: 31785910, PMCID: PMC6957748, DOI: 10.1016/j.scitotenv.2019.134719.Peer-Reviewed Original ResearchConceptsLife eventsLinear regression modelsMultiple linear regression modelNegative life eventsPresence of negative life eventsPsychosocial stress measuresAdverse birth outcomesPregnancy cohort studyRegression modelsEffects of psychosocial stressPsychosocial factorsNon-chemical stressorsBirth outcomesEffects of life eventsCohort studyPsychosocial stressPositive LEsPositive life eventsExposure biomarkersSignificant modifiersPrenatal exposureSignificant interactionWomenAssociationRate of events
2017
Personality and Life Events in a Personality Disorder Sample
Timoney LR, Walsh Z, Shea MT, Yen S, Ansell EB, Grilo CM, McGlashan TH, Stout RL, Bender DS, Skodol AE, Sanislow CA, Morey LC, Gunderson JG. Personality and Life Events in a Personality Disorder Sample. Personality Disorders Theory Research And Treatment 2017, 8: 376-382. PMID: 27797543, PMCID: PMC5411350, DOI: 10.1037/per0000214.Peer-Reviewed Original ResearchConceptsPositive life eventsNegative life eventsLife eventsNormal personality traitsPersonality disorderPersonality traitsCommunity sampleFFM traitsPD groupLives of individualsPresent researchPersonalityMajor depressive disorderFactor modelClinical samplesIndividualsControl groupDepressive disorderConscientiousnessAvoidantExtraversionDisordersNeuroticismTraitsSchizotypal
2013
Functional outcomes of maltreated children and adolescents in a community-based rehabilitation program in Brazil: Six-month improvement and baseline predictors
Stefanovics EA, Filho MV, Rosenheck RA, Scivoletto S. Functional outcomes of maltreated children and adolescents in a community-based rehabilitation program in Brazil: Six-month improvement and baseline predictors. Child Abuse & Neglect 2013, 38: 1231-1237. PMID: 24300697, DOI: 10.1016/j.chiabu.2013.10.025.Peer-Reviewed Original ResearchConceptsCommunity-based rehabilitation programGlobal Assessment ScaleRehabilitation programOutcome monitoringSix-month improvementsChildren's Global Assessment ScaleSpecific evidence-based treatmentsSpecific psychiatric diagnosesEvidence-based treatmentsAnalysis of outcomesUntreated control groupCommunity-based programsModerate effect sizeFunctional outcomeBaseline predictorsOutcome dataPsychiatric diagnosisControl groupAssessment ScaleFunctional changesNegative life eventsLife eventsEffect sizeChildrenPhysical abuse
2009
Rumination and intentional forgetting of emotional material
Joormann J, Tran T. Rumination and intentional forgetting of emotional material. Cognition & Emotion 2009, 23: 1233-1246. DOI: 10.1080/02699930802416735.Peer-Reviewed Original ResearchEmotional materialRuminative Response ScaleIntentional forgettingNegative mood statesNegative life eventsMaladaptive response stylesRemember conditionForget conditionEmotion dysregulationIndividual differencesRuminative thinkingNegative wordsEmotional disordersResponse stylesMood statesLife eventsRuminationForgettingResponse scaleWordsDepressive symptomsDepression scoresParticipantsRecallNew list
2007
Sources of Stress and Support and Maternal Resources of Homeless Teenage Mothers
Meadows‐Oliver M, Sadler LS, Swartz MK, Ryan‐Krause P. Sources of Stress and Support and Maternal Resources of Homeless Teenage Mothers. Journal Of Child And Adolescent Psychiatric Nursing 2007, 20: 116-125. PMID: 17598805, DOI: 10.1111/j.1744-6171.2007.00093.x.Peer-Reviewed Original Research
2006
Suicidal Ideation in Veterans Receiving Treatment for Opiate Dependence
Thompson R, Kane V, Cook JM, Greenstein R, Walker P, Woody G. Suicidal Ideation in Veterans Receiving Treatment for Opiate Dependence. Journal Of Psychoactive Drugs 2006, 38: 149-156. PMID: 16903454, DOI: 10.1080/02791072.2006.10399839.Peer-Reviewed Original ResearchConceptsSuicidal ideationOpiate dependenceUrban VA medical centerSevere chronic painOpiate use disorderVA Medical CenterMental health issuesChronic painImmediate hospitalizationFrequent screeningMedical CenterUse disordersRecent negative life eventsStreet drugsInitial evaluationHealth issuesNegative life eventsAcute indicatorsVeteransCurrent ideationIdeationTreatmentLife eventsFamily membersRoutine basisDifferential Effects of Rumination and Dysphoria on the Inhibition of Irrelevant Emotional Material: Evidence from a Negative Priming Task
Joormann J. Differential Effects of Rumination and Dysphoria on the Inhibition of Irrelevant Emotional Material: Evidence from a Negative Priming Task. Cognitive Therapy And Research 2006, 30: 149-160. DOI: 10.1007/s10608-006-9035-8.Peer-Reviewed Original ResearchResponse Styles QuestionnaireEmotional wordsPriming taskIndividual differencesNegative affective priming taskIrrelevant emotional materialIrrelevant emotional stimuliAffective priming taskSelf-referential judgmentsNegative priming taskNegative mood statesNegative life eventsEmotional materialCognitive processesEmotional stimuliRuminative responsesMood statesDevelopment of depressionLife eventsStyle QuestionnaireInhibitory dysfunctionLow scorersRuminationCurrent depression scoresGroup differences
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