2025
Development and validation of Comprehensive Inflammatory Lifestyle Score and association with colorectal cancer risk.
Zheng J, Zhao L, Dong J, Giovannucci E. Development and validation of Comprehensive Inflammatory Lifestyle Score and association with colorectal cancer risk. Cancer Epidemiology Biomarkers & Prevention 2025 PMID: 40704925, DOI: 10.1158/1055-9965.epi-25-0386.Peer-Reviewed Original ResearchLifestyle scoreUK BiobankLifestyle factorsColorectal cancerAssociated with CRC riskRisk of colorectal cancerMortality riskBaseline lifestyle factorsColorectal cancer incidenceAssociated with colorectal cancerColorectal cancer riskHigh-sensitivity C-reactive proteinWhite blood countCRC riskNon-dietary factorsColorectal cancer subtypesLinear regressionCancer riskSD incrementCancer preventionRank regressionMultiple linear regressionCox modelValidity analysisLifestyle
2024
Parent-Clinician Communication and Prolonged Grief in Parents Whose Child Died From Cancer
Ouyang N, Baker J, Ananth P, Knobf M, Snaman J, Feder S. Parent-Clinician Communication and Prolonged Grief in Parents Whose Child Died From Cancer. Journal Of Pain And Symptom Management 2024, 68: 516-524.e1. PMID: 39142495, DOI: 10.1016/j.jpainsymman.2024.08.003.Peer-Reviewed Original ResearchEnd-of-lifeParent-clinician communicationProlonged grief symptomsGrief symptomsChild's end-of-lifeCross-sectional survey of parents of childrenEnd-of-life careHigh-quality end-of-lifeProlonged griefSum scoreSurvey of parents of childrenCross-sectional surveyParents of childrenAdequate prognostic informationBereaved parentsPrognostic informationChild deathsParents' experiencesMultiple linear regressionPG-13Analyzed dataLinear regressionAssociationGriefChildrenBlood mercury mediates the associations between fish consumption and serum uric acid levels among Chinese adults: A nationally representative study
Wu C, Wu B, Qu Y, Fu H, Chen Y, Lu Y, Ji S, Ding L, Li Z, Sun Q, Zhang M, Zhang X, Ying B, Zhao F, Zheng X, Qiu Y, Zhang Z, Li K, Zhu Y, Cao Z, Lv Y, Shi X. Blood mercury mediates the associations between fish consumption and serum uric acid levels among Chinese adults: A nationally representative study. Environmental Research 2024, 260: 119612. PMID: 39004394, DOI: 10.1016/j.envres.2024.119612.Peer-Reviewed Original ResearchFish consumption frequencyFish consumptionBlood mercurySerum uric acid levelsSafety of fish consumptionSerum uric acidEnrichment of mercuryConsumption frequencyMercury pollutionConsuming fishHuman biomonitoringSUA levelsMercuryFishBHGIncreased serum uric acidAssociated with SUA levelsNationally Representative StudyWeighted multiple linear regressionUric acid levelsGlomerular filtration functionMultiple linear regressionChinese adultsRepresentative studyPurine loadingThe Effects of Age and Height on Gait Smoothness in Adolescent Athletes †
Clarke L, Jones R, Hiremath S, Franklin C, Wright W, Tucker C. The Effects of Age and Height on Gait Smoothness in Adolescent Athletes †. Children 2024, 11: 223. PMID: 38397335, PMCID: PMC10887815, DOI: 10.3390/children11020223.Peer-Reviewed Original ResearchGait stabilityPost-fatigueRate of sports injuriesBout of fatiguing exerciseTrials of treadmillQuantify gait stabilityEffects of fatigueWalking speedAdolescent athletesPre-fatigueSports injuriesChronological ageGaitMultiple linear regressionEffects of ageStudy findingsTreadmillSport progressionAdolescent growthAdolescentsLinear regressionWalkingFemale adolescentsFatigueMale heightAssociations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study
Xing Y, Li Z, Wang J, Qu Y, Hu Q, Ji S, Chang X, Zhao F, Lv Y, Pan Y, Shi X, Dai J. Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study. Environment International 2024, 184: 108459. PMID: 38320373, DOI: 10.1016/j.envint.2024.108459.Peer-Reviewed Original ResearchConceptsRestricted cubic splinesBayesian kernel machine regressionNationally representative cross-sectional studyNonlinear dose-response associationDose-response associationChinese adult populationWeighted multiple linear regressionGeneral Chinese populationCross-sectional studyNationally representative dataYounger age groupsKernel machine regressionChinese adultsInverse associationG-computationPerfluoroheptane sulfonic acidQuantile-based g-computationAdult populationRepresentative dataSignificant associationPositive associationThyroid homeostasisChinese populationMultiple linear regressionAge groups
2023
Long-term exposure to ambient air pollution and inflammatory response in the KORA study
Vogli M, Peters A, Wolf K, Thorand B, Herder C, Koenig W, Cyrys J, Maestri E, Marmiroli N, Karrasch S, Zhang S, Pickford R. Long-term exposure to ambient air pollution and inflammatory response in the KORA study. The Science Of The Total Environment 2023, 912: 169416. PMID: 38123091, DOI: 10.1016/j.scitotenv.2023.169416.Peer-Reviewed Original ResearchConceptsLong-term exposure to ambient air pollutionLong-term exposure to air pollutionExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAir pollutionUltrafine particlesParticulate matterIncrease of PM<sLand-use regression modelsAnnual mean concentrationsAtmospheric particulate matterAssociated with increased IL-6Adverse health effectsAssociated with higher concentrationsLand-useMean concentrationsParticipant's home addressPollutionLong-term studiesHealth effectsHigher concentrationsNitrogen oxidesMultiple linear regressionHome address
2021
Measuring Proximal Tibial Metaphyseal Width and Lateral Epiphyseal Height Improves Determination of Remaining Growth in Children
Kahan JB, Li DT, Schneble CA, Elabd A, Attia E, Esparza R, Cui JJ, Li E, Moran J, Smith BG, Cooperman DR. Measuring Proximal Tibial Metaphyseal Width and Lateral Epiphyseal Height Improves Determination of Remaining Growth in Children. Journal Of Pediatric Orthopaedics 2021, 41: e739-e744. PMID: 34325444, DOI: 10.1097/bpo.0000000000001853.Peer-Reviewed Original ResearchConceptsFull-length radiographsEpiphyseal heightInclusion criteriaPediatric patient populationMetabolic bone diseaseOrthopedic surgical interventionMultivariable regression modelsPrior surgeryRegression modelsSurgical interventionPatient populationPrevious infectionKnee radiographsProximal tibiaBone diseaseLevel IIIMetaphyseal widthSkeletal maturityRadiographsFinal heightMultiple linear regressionQuantitative markerLinear regressionAge 16ChildrenCross-Sectional Estimation of Endogenous Biomarker Associations with Prenatal Phenols, Phthalates, Metals, and Polycyclic Aromatic Hydrocarbons in Single-Pollutant and Mixtures Analysis Approaches
Aung M, Yu Y, Ferguson K, Cantonwine D, Zeng L, McElrath T, Pennathur S, Mukherjee B, Meeker J. Cross-Sectional Estimation of Endogenous Biomarker Associations with Prenatal Phenols, Phthalates, Metals, and Polycyclic Aromatic Hydrocarbons in Single-Pollutant and Mixtures Analysis Approaches. Environmental Health Perspectives 2021, 129: 037007. PMID: 33761273, PMCID: PMC7990518, DOI: 10.1289/ehp7396.Peer-Reviewed Original ResearchConceptsExposure analytesToxicity classesMixtures of toxicantsSingle-pollutant modelsPolycyclic aromatic hydrocarbonsHierarchical Bayesian kernel machine regressionBayesian kernel machine regressionKernel machine regressionPrenatal toxicant exposureAdaptive elastic net regressionClasses of toxicantsSingle-pollutantTrace metalsAromatic hydrocarbonsToxic mixturePair-wise associationsAdaptive elastic netToxicant exposurePhthalateMachine regressionEndogenous biomarkersBiomarkers indicativeMultiple linear regressionMetalToxicity
2016
Glucosylsphingosine is a key biomarker of Gaucher disease
Murugesan V, Chuang W, Liu J, Lischuk A, Kacena K, Lin H, Pastores GM, Yang R, Keutzer J, Zhang K, Mistry PK. Glucosylsphingosine is a key biomarker of Gaucher disease. American Journal Of Hematology 2016, 91: 1082-1089. PMID: 27441734, PMCID: PMC5234703, DOI: 10.1002/ajh.24491.Peer-Reviewed Original ResearchConceptsEnzyme replacement therapyLyso-GL1GD type 1Gaucher diseasePropensity scoreUntreated GD patientsWilcoxon Mann-Whitney testAccumulation of glucosylceramideMann-Whitney testTreatment modeImmune dysregulationCCL18 levelsReplacement therapyGD patientsHealthy controlsPropensity scoringPatientsSkeletal diseaseType 1Comparable groupsMarked reductionMultiple linear regressionSignificant predictorsKey biomarkersLinear regressionEmotional Distress and Burden Among Caregivers of Children With Oncological/Hematological Disorders
Edmond SN, Graves PE, Whiting SE, Karlson CW. Emotional Distress and Burden Among Caregivers of Children With Oncological/Hematological Disorders. Families Systems & Health 2016, 34: 166-171. PMID: 26963775, DOI: 10.1037/fsh0000181.Peer-Reviewed Original ResearchConceptsCaregiver emotional distressCaregiver burdenChildren's symptomsChildren's painCaregiver distressEmotional distressChild demographic dataChild sleep problemsCross-sectional designSleep problemsHematological disordersDemographic dataSymptomsPainBurdenDistressBehavioral problemsFinancial difficultiesCaregiversLongitudinal designGreater childChildrenSelf-reported survey dataMultiple linear regressionLinear regression
2011
Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods
Han L, Kim N, Brandt C, Allore HG. Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods. Annals Of Epidemiology 2011, 22: 9-16. PMID: 22037381, PMCID: PMC4054866, DOI: 10.1016/j.annepidem.2011.10.004.Peer-Reviewed Original ResearchConceptsDepression-related diagnosisAntidepressant useDepression symptomsOlder personsPropensity scoreHopkins Verbal Learning TestHypertensive menAntidepressant medicationIndication biasVerbal Learning TestMedical recordsPotential confoundingCumulative exposureOlder menCognitive impairmentMemory deficitsCognitive deficitsMultiple linear regressionLinear regressionLearning TestApparent associationScoresSymptomsDiagnosisIndicationsDistinct but overlapping neural networks subserve depression and insecure attachment
Galynker II, Yaseen ZS, Katz C, Zhang X, Jennings-Donovan G, Dashnaw S, Hirsch J, Mayberg H, Cohen LJ, Winston A. Distinct but overlapping neural networks subserve depression and insecure attachment. Social Cognitive And Affective Neuroscience 2011, 7: 896-908. PMID: 22037687, PMCID: PMC3501706, DOI: 10.1093/scan/nsr074.Peer-Reviewed Original ResearchConceptsSub-cortical activityBeck Depression InventoryEffect of depressionLevel-dependent responsesSub-cortical componentsCortico-striatoCortical effectsDepression scoresThalamic circuitsDepression InventoryCortical encodingDepressionFMRI scanningBrain activityNeural mechanismsPsychotherapeutic outcomeInsecure attachmentScoresSame circuitryFemale strangerMultiple linear regressionLater attachmentLinear regressionPatientsAttachment insecurity
2005
A case study found that a regression tree outperformed multiple linear regression in predicting the relationship between impairments and Social and Productive Activities scores
Allore H, Tinetti ME, Araujo KL, Hardy S, Peduzzi P. A case study found that a regression tree outperformed multiple linear regression in predicting the relationship between impairments and Social and Productive Activities scores. Journal Of Clinical Epidemiology 2005, 58: 154-161. PMID: 15680749, DOI: 10.1016/j.jclinepi.2004.09.001.Peer-Reviewed Original Research
2001
Preference for disclosure of information among patients with rheumatoid arthritis
Fraenkel L, Bogardus S, Concato J, Felson D. Preference for disclosure of information among patients with rheumatoid arthritis. Arthritis & Rheumatism 2001, 45: 136-139. PMID: 11324776, DOI: 10.1002/1529-0131(200104)45:2<136::aid-anr165>3.0.co;2-p.Peer-Reviewed Original ResearchConceptsRheumatoid arthritisRA patientsSex-specific analysesSex-specific correlatesInformation preferencesPatient characteristicsTherapeutic optionsFemale sexSide effectsPatientsBivariate analysisHigher education levelCurrent employmentArthritisMean scoreEducation levelAlternative optionRiskFull disclosureOptionsMultiple linear regressionLinear regressionStepwise multiple linear regressionMedicationsRheumatologists
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply