2025
Cost Disparities with Age in the Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC) in Ontario, Canada
Wang Y, Pond G, Gafni A, Kong C, Ellis P. Cost Disparities with Age in the Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC) in Ontario, Canada. Current Oncology 2025, 32: 346. PMID: 40558289, PMCID: PMC12191781, DOI: 10.3390/curroncol32060346.Peer-Reviewed Original ResearchConceptsCancer-attributable costsPhase of careNon-small-cell lung cancerAdvanced non-small-cell lung cancerInstitute for Clinical Evaluative SciencesHealthcare costsEnd-of-lifePre-diagnosis costsCost disparityEnd-of-life phaseDiagnosis of advanced non-small-cell lung cancerStage IV non-small-cell lung cancerTreatment of advanced non-small-cell lung cancerIV non-small-cell lung cancerRetrospective cohort studyLung cancerEvaluative SciencesPre-DiagnosisCancer diagnosisCohort studyOlder patientsDeceased patientsCareReceiving chemotherapyMedian ageEvaluating palliative care needs of early-phase clinical trial patients.
Crowley F, Zeng L, Hobensack M, Lehrman S, Afezolli D, Kelly L, Wey W, Chen J, Austin V, Easton E, Pagala A, Wu K, Lucas N, Wilk J, Marron T, Smith C, Gelfman L, Doroshow D. Evaluating palliative care needs of early-phase clinical trial patients. Journal Of Clinical Oncology 2025, 43: 12086-12086. DOI: 10.1200/jco.2025.43.16_suppl.12086.Peer-Reviewed Original ResearchPalliative careEnd-of-lifeEarly phase clinical trialsOutpatient PCReferral systemPalliative care needsSpecialty palliative careCancer type distributionPC servicesCare needsRetrospective cohort studyEvaluate demographic characteristicsPrevalent symptomsRate of constipationPC guidelinesPhysical discomfortCohort studyIncrease accessFisher's exact testPhase clinical trialsClinical trial patientsDemographic characteristicsMann-Whitney U testChi-squareCategorical variablesAdvance care planning documentation prior to end-of-life systemic therapy: A single institution retrospective review.
Xiang J, Wiese B, Patlovich K, Taylor J, Adelson K, Ratan R. Advance care planning documentation prior to end-of-life systemic therapy: A single institution retrospective review. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e24031.Peer-Reviewed Original ResearchSystemic anticancer therapyMonths of lifeTargeted therapyDose of treatmentAdvance care planning notesFinal treatmentAdvance care planningEnd-of-lifeHigher risk of mortalityDocumented discussionAssociated with decreased quality of lifeRisk of mortalityAssociated with decreased qualityMetastatic diseaseHigh healthcare useInpatient settingSolid tumorsRetrospective studyMD AndersonCellular therapyMedical oncologistsAnticancer therapyImmunotherapyTherapyPatientsPalliative care in acute care surgery: research challenges and opportunities
Maiga A, Ho V, Morris R, Kodadek L, Puzio T, Tominaga G, Tabata-Kelly M, Cooper Z. Palliative care in acute care surgery: research challenges and opportunities. Trauma Surgery & Acute Care Open 2025, 10: e001615. PMID: 40124208, PMCID: PMC11927415, DOI: 10.1136/tsaco-2024-001615.Peer-Reviewed Original ResearchAcute care surgeryPalliative care researchPalliative careCare researchEnd-of-life carePractice palliative carePalliative care interventionsPrimary palliative careSpecialty palliative careLife-prolonging careEnd-of-lifeRelief of sufferingQuality of lifeHigh-quality researchCare interventionsSymptom managementAdministrative dataAcute care surgeonsCareEmergency surgical conditionsSurgical illnessPrimary data collectionEffective communicationNarrative reviewCritical surgical illness
2024
LINKING DEMENTIA CAREGIVING EXPERIENCES WITH EXPECTATIONS OF FUTURE HEALTH CARE NAVIGATION
Bloom R, Lou Y, Monin J, Fried T, Falzarano F, Mroz E. LINKING DEMENTIA CAREGIVING EXPERIENCES WITH EXPECTATIONS OF FUTURE HEALTH CARE NAVIGATION. Innovation In Aging 2024, 8: 267-267. PMCID: PMC11690495, DOI: 10.1093/geroni/igae098.0864.Peer-Reviewed Original ResearchEnd-of-lifeImprove end-of-life experiencesPerception of hospice careEnd-of-life experiencesDementia caregiving experienceCaregivers of peopleReduce care fragmentationGoals of careHealth care navigationMedical advocacyReflexive thematic analysisAnalysis of semi-structured interviewsFeelings of preparednessSemi-structured interviewsBereaved caregiversDementia caregiversAdvanced dementiaCare navigationHealthcare coordinationCaregiving experienceHospice careCare fragmentationCaregiver expectationsCare expectationsCaregiver observationsARE CAREGIVERS MORE LIKELY TO ENGAGE IN ADVANCE CARE PLANNING? EXAMINATION BY RACE AND ETHNICITY
Lou Y, Mroz E, Fried T, Zang E. ARE CAREGIVERS MORE LIKELY TO ENGAGE IN ADVANCE CARE PLANNING? EXAMINATION BY RACE AND ETHNICITY. Innovation In Aging 2024, 8: 267-267. PMCID: PMC11690644, DOI: 10.1093/geroni/igae098.0865.Peer-Reviewed Original ResearchAdvance care planningAdvance care planning outcomesAdvance care planning behaviorsNon-dementia caregiversDementia caregiversCaregiving experienceNon-dementiaSpousal caregiversNon-caregiversCare planningHispanic participantsEnd-of-life care wishesAdvance care planning discussionsHealth and Retirement StudySpousal caregiving experienceEffects of caregiving experiencesEnd-of-lifeDeclining quality of lifeQuality of lifeCare wishesCaregiver groupsWhite caregiversCare recipientsHealth covariatesRetirement StudyEMERGENCY DEPARTMENT USE AND HEALTH CARE EXPENDITURES AMONG OLDER ADULTS AT END-OF-LIFE
Gettel C, Kitchen C, Rothenberg C, Song Y, Venkatesh A, Hastings S. EMERGENCY DEPARTMENT USE AND HEALTH CARE EXPENDITURES AMONG OLDER ADULTS AT END-OF-LIFE. Innovation In Aging 2024, 8: 43-43. PMCID: PMC11689632, DOI: 10.1093/geroni/igae098.0130.Peer-Reviewed Original ResearchEnd-of-lifeED visitsMedicare beneficiariesED useTerminal phase of lifeEnd-of-life careHealthcare spendingEmergency departmentMedicare Current Beneficiary SurveyEmergency department usePrimary outcomeOut-of-pocket (OOPTotal health care spendingCommunity serviceZero-inflated negative binomial regression modelsHealth care expendituresHealth care spendingTotal healthcare spendingNegative binomial regression modelsCross-sectional analysisAdult decedentsBinomial regression modelsDepartment useInadequate accessPhase of lifeIMPLEMENTATION OF COMMUNITY-BASED PALLIATIVE CARE: A SYSTEMATIC SCOPING REVIEW
Ho D, Dissault N, Vick J, Skalla L, Dukkipati H, Ma J, Kaufman B. IMPLEMENTATION OF COMMUNITY-BASED PALLIATIVE CARE: A SYSTEMATIC SCOPING REVIEW. Innovation In Aging 2024, 8: 233-233. PMCID: PMC11689857, DOI: 10.1093/geroni/igae098.0753.Peer-Reviewed Original ResearchCommunity-based palliative carePalliative careSystematic scoping reviewPerceived BarriersScoping ReviewProvider perspectiveEnd-of-life careSocial needs resourcesLeadership buy-inInter-provider communicationEnd-of-lifeReviewers screened articlesImprove quality of lifeQuality of lifePC teamIllness carePC educationCare partnersFramework synthesisProvider levelCategorize themesPractice settingsSpecialty clinicsNeeds resourcesProgram implementationClinical Ethics and the Observant Jewish and Muslim Patient: Shared Theocentric Perspectives in Practice.
Hossain F, Gabbay E, Fins J. Clinical Ethics and the Observant Jewish and Muslim Patient: Shared Theocentric Perspectives in Practice. Cambridge Quarterly Of Healthcare Ethics 2024, 1-17. PMID: 39575535, DOI: 10.1017/s0963180124000379.Peer-Reviewed Original ResearchMedical ethicsEnd-of-life decisionsWestern medical ethicsTheocentric perspectiveFaith traditionsClinical ethicsOrthodox JudaismReligious minoritiesMoral codeReligious beliefsReligious observanceEnd-of-lifeMuslim patientsEthicsPatient's health goalsTheocentrismMedical contextTraditionCultural valuesBeliefsHealth goalsGodJudaismMental healthIslamA cradle‐to‐grave life cycle assessment of the endoscopic sinus surgery considering materials, energy, and waste
Mousania Z, Kayastha D, Rimmer R, Atkinson J. A cradle‐to‐grave life cycle assessment of the endoscopic sinus surgery considering materials, energy, and waste. International Forum Of Allergy & Rhinology 2024, 15: 239-249. PMID: 39462253, DOI: 10.1002/alr.23474.Peer-Reviewed Original ResearchLife cycle assessmentGlobal warming potentialEnvironmental impactCycle assessmentCradle-to-grave life cycle assessmentEnd-of-life waste managementWater use impactsWaste-to-energy incinerationHigh greenhouse gas emissionsSingle-use itemsGreenhouse gas emissionsPlastic itemsWaste-to-energyComprehensive LCAWarming potentialWaste managementEnvironmental benefitsGas emissionsSingle-useIncinerationEnergy consumptionWasteEnd-of-lifeMulti-userLife cycleAsynchronous education improves emergency medical services clinician confidence and knowledge in caring for patients near the end‐of‐life
Wang D, Dunn C, Brooten J, Gacioch B, Taigman M, He Z, Dziura J, Breyre A. Asynchronous education improves emergency medical services clinician confidence and knowledge in caring for patients near the end‐of‐life. Journal Of The American College Of Emergency Physicians Open 2024, 5: e13331. PMID: 39449818, PMCID: PMC11499566, DOI: 10.1002/emp2.13331.Peer-Reviewed Original ResearchEmergency medical services cliniciansEmergency medical servicesEmergency medical services agenciesYears of experienceYears of EMS experienceClinician confidencePalliative care expertiseCommunication skillsEnd-of-lifeDelivering bad newsDistrict of ColumbiaHospice knowledgeCare expertiseLinear regressionModule completionClinician knowledgeMedical servicesHospiceBad newsEM experimentsImprove confidenceLikert-scaleCliniciansOnline curriculumLevel of certificationSystemic anti-cancer treatment and healthcare utilization at end of life: A SEER Medicare analysis.
Adelson K, Canavan M, Niu J, Zhao H, Nortje N, Xiang J, Giordano S, Cheng L. Systemic anti-cancer treatment and healthcare utilization at end of life: A SEER Medicare analysis. Journal Of Clinical Oncology 2024, 20: 276-276. DOI: 10.1200/op.2024.20.10_suppl.276.Peer-Reviewed Original ResearchEnd-of-lifeSystemic anticancer therapyDay of deathIntensive care unit useIntensive care unitHealthcare utilizationEmergency departmentCombined chemo-immunotherapyEnd-of-life chemotherapy useAssociated with healthcare utilizationImmunotherapy useChemo-ImmunotherapyIncreased healthcare useEnd of lifeAdverse quality of lifeAssociated with higher EDCare unitQuality of lifeSystemic anti-cancer treatmentHospice useDay hospiceHospice enrollmentSEER-Medicare databaseUse of chemotherapyHealthcare useEnd‐of‐life emergency department use and healthcare expenditures among older adults: A nationally representative study
Gettel C, Kitchen C, Rothenberg C, Song Y, Hastings S, Kennedy M, Ouchi K, Haimovich A, Hwang U, Venkatesh A. End‐of‐life emergency department use and healthcare expenditures among older adults: A nationally representative study. Journal Of The American Geriatrics Society 2024, 73: 101-111. PMID: 39311623, PMCID: PMC11735276, DOI: 10.1111/jgs.19199.Peer-Reviewed Original ResearchEnd-of-lifeOut-of-pocket spendingED visitsTotal healthcare spendingMedicare beneficiariesHealthcare spendingEmergency departmentOlder adultsMedicare Current Beneficiary Survey dataAnalysis of Medicare beneficiariesPooled cross-sectional analysisEmergency department usePrimary outcomeDecreased likelihoodDiagnosis of dementiaOut-of-pocket costsNationally Representative StudyNationally Representative SampleAdult decedentsHospice statusDepartment useED useED servicesHealth careHealthcare expendituresTop Ten Tips Palliative Care Clinicians Should Know About Caring for Patients Under Guardianships
Bhowmik D, Hurme S, Sandhu J, Jeon J, Mujahid S, Pelissier L, Widera E, Cohen A, Kohn N, Galvez M, Alkire V, Teaster P, Rosa W, Pan C. Top Ten Tips Palliative Care Clinicians Should Know About Caring for Patients Under Guardianships. Journal Of Palliative Medicine 2024 PMID: 39291357, DOI: 10.1089/jpm.2024.0318.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPalliative care cliniciansCare cliniciansCoordination of careMedical decision-making processEnd-of-lifeDecision-making processLegal issuesLegal rightsMedical decision-makingPatients' rightsCare deliveryExpertise of physiciansGuardianshipInterprofessional approachProviding careGuardian responsibilitiesCareGuardiansRightsCliniciansAdult patientsDecision-makingCourtLawyersNursesHarnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer
Lindsay M, de Oliveira S, Sciacca K, Lindvall C, Ananth P. Harnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer. JCO Clinical Cancer Informatics 2024, 8: e2400134. PMID: 39265122, PMCID: PMC11407740, DOI: 10.1200/cci.24.00134.Peer-Reviewed Original ResearchConceptsEnd-of-life carePalliative care consultationGoals of careLocation of deathProportion of decedentsDocumented discussionCare consultationEvidence-based quality measuresMeasure quality of careGold standard manual chart reviewQuality measuresQuality of careEnd of lifeContent of clinical notesLife-sustaining treatmentEnd-of-lifeManual chart reviewCancer decedentsEfficient quality measureCohort of childrenAssess qualityMulti-center researchQuality improvementMeasure qualityCareLeveraging an Electronic Health Record Patient Portal to Help Patients Formulate Their Health Care Goals: Mixed Methods Evaluation of Pilot Interventions
Naimark J, Tinetti M, Delbanco T, Dong Z, Harcourt K, Esterson J, Charpentier P, Walker J. Leveraging an Electronic Health Record Patient Portal to Help Patients Formulate Their Health Care Goals: Mixed Methods Evaluation of Pilot Interventions. JMIR Formative Research 2024, 8: e56332. PMID: 39207829, PMCID: PMC11393498, DOI: 10.2196/56332.Peer-Reviewed Original ResearchConceptsPatient portalsPatient prioritiesElectronic health record patient portalEnd-of-life carePatient Priorities CareFamily medicine practiceMixed methods evaluationHealth care goalsComplex medication regimensEnd-of-lifeMedian completion timeMedian session timePrevisit questionnaireCare goalsInvited patientsPilot interventionPriority careSession timeHealth priorityFocus groupsPhone interviewsYears of ageMedication regimensMedicine practiceEPIC questionnaireParent-Clinician Communication and Prolonged Grief in Parents Whose Child Died From Cancer
Ouyang N, Baker J, Ananth P, Knobf M, Snaman J, Feder S. Parent-Clinician Communication and Prolonged Grief in Parents Whose Child Died From Cancer. Journal Of Pain And Symptom Management 2024, 68: 516-524.e1. PMID: 39142495, DOI: 10.1016/j.jpainsymman.2024.08.003.Peer-Reviewed Original ResearchEnd-of-lifeParent-clinician communicationProlonged grief symptomsGrief symptomsChild's end-of-lifeCross-sectional survey of parents of childrenEnd-of-life careHigh-quality end-of-lifeProlonged griefSum scoreSurvey of parents of childrenCross-sectional surveyParents of childrenAdequate prognostic informationBereaved parentsPrognostic informationChild deathsParents' experiencesMultiple linear regressionPG-13Analyzed dataLinear regressionAssociationGriefChildren“What Matters” in the Emergency Department
Chera T, Tinetti M, Travers J, Galske J, Venkatesh A, Southerland L, Dresden S, McQuown C, Gettel C. “What Matters” in the Emergency Department. Medical Care 2024, 62: s50-s56. PMID: 39514495, PMCID: PMC11548826, DOI: 10.1097/mlr.0000000000002053.Peer-Reviewed Original ResearchConceptsOlder adultsEmergency departmentEmergency careED visitsAssociated with meetingAssociated with older adultsEnd-of-lifeFollow-upPatient characteristicsMultivariate logistic regression modelCare of oneselfLogistic regression modelsFollow-up interviewsMulticenter prospective observational studyHealthcare settingsED encountersFunctional independenceProspective observational studySecondary analysisSymptom identificationAssess concernsSecondary outcomesPrimary outcomeCareObservational studyQuality of Care in the Last Two Years of Life for Children With Complex Chronic Conditions
Bogetz J, Strub B, Bradford M, McGalliard J, Shipman K, Jeyte A, Patneaude A, Johnston E, Ananth P, Thienprayoon R, Rosenberg A. Quality of Care in the Last Two Years of Life for Children With Complex Chronic Conditions. Journal Of Pain And Symptom Management 2024, 68: 488-498.e1. PMID: 39097243, DOI: 10.1016/j.jpainsymman.2024.07.034.Peer-Reviewed Original ResearchComplex chronic conditionsEnd-of-life quality measuresEnd-of-lifeChronic conditionsHealthcare servicesQuality EOL careQuality measuresQuality of careICD-10 diagnosis codesEvaluate demographic differencesU.S. children's hospitalsYears of lifeEOL careDied in-hospitalInterprofessional supportSymptom managementHealthcare utilizationHospital performanceMedication intensityNon-HispanicDiagnosis codesDescriptive statisticsCardiopulmonary resuscitationChildren's HospitalPublic insuranceTrends in use of intensive care during hospitalizations at the end‐of‐life among older adults with advanced cancer
Jain S, Long J, Rao V, Law A, Walkey A, Prsic E, Lindenauer P, Krumholz H, Gross C. Trends in use of intensive care during hospitalizations at the end‐of‐life among older adults with advanced cancer. Journal Of The American Geriatrics Society 2024, 72: 3840-3848. PMID: 39090970, PMCID: PMC11637920, DOI: 10.1111/jgs.19119.Peer-Reviewed Original ResearchEnd-of-life hospitalizationsLife-sustaining treatmentEnd-of-lifeIntensity of careIn-Hospital DeathOlder adultsIntensive care unitAdvanced cancerRisk-adjusted hospitalEvaluate trendsIncreased intensity of careIntensive care unit useSEER-Medicare dataIntensive care unit careMultinomial regression modelsYear of diagnosisIntensive careHospital categoryMedicare beneficiariesSEER-MedicareHospitalization ratesCareCancer characteristicsNoninvasive ventilationHospital
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