2024
Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA)
Maayah M, Latif N, Vijay A, Gallegos C, Cigarroa N, Martinez E, Mazure C, Miller E, Spatz E, Shah S. Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA). Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 3: 102195. PMID: 39166160, PMCID: PMC11330936, DOI: 10.1016/j.jscai.2024.102195.Peer-Reviewed Original ResearchIschemic heart diseaseNonobstructive coronary arteriesCoronary artery diseaseArtery diseaseObstructive coronary artery diseaseCoronary arteryLong-term cardiovascular prognosisHeart diseaseSuspected ischemic heart diseaseAtherosclerotic coronary artery diseaseCoronary vasomotor disordersPretest probability of diseasePragmatic diagnostic algorithmExpert consensus documentEvaluating ischemic heart diseaseImpact quality of lifeQuality of lifeSymptomatic patientsPretest probabilityANOCACardiovascular prognosisVasomotor disordersDiagnostic evaluationPersistent symptomsDiagnostic strategies
2023
Scaling up evidence-based approaches to tuberculosis screening in prisons
Charalambous S, Velen K, Rueda Z, Croda J, Herce M, Shenoi S, Altice F, Muyoyeta M, Telisinghe L, Grandjean L, Keshavjee S, Andrews J. Scaling up evidence-based approaches to tuberculosis screening in prisons. The Lancet Public Health 2023, 8: e305-e310. PMID: 36780916, DOI: 10.1016/s2468-2667(23)00002-6.Commentaries, Editorials and LettersConceptsIncidence of tuberculosisCase-finding strategyHigh tuberculosis burdenMinistry of HealthEvidence-based approachTuberculosis burdenTreatment cascadeTuberculosis screeningTuberculosis notificationsTuberculosis diagnosisGeneral populationCare programDiagnostic strategiesTuberculosisEvidence baseSystematic screeningHigh rateIncidenceScreeningSetting
2022
Recent Advances in the Rheumatic Fever and Rheumatic Heart Disease Continuum
Rwebembera J, Nascimento B, Minja N, de Loizaga S, Aliku T, dos Santos L, Galdino B, Corte L, Silva V, Chang A, Dutra W, Nunes M, Beaton A. Recent Advances in the Rheumatic Fever and Rheumatic Heart Disease Continuum. Pathogens 2022, 11: 179. PMID: 35215123, PMCID: PMC8878614, DOI: 10.3390/pathogens11020179.Peer-Reviewed Original ResearchRheumatic heart diseaseHuman immunodeficiency virusRheumatic feverLatent rheumatic heart diseaseManagement of rheumatic heart diseaseGroup A <i>Streptococcus</i>Burden of rheumatic heart diseaseSecondary antibiotic prophylaxisAntibiotic prophylaxisGAS pharyngitisEchocardiographic screeningImmunodeficiency virusDiagnostic strategiesHeart diseaseTertiary managementVaccine developmentMiddle-income countriesNarrative reviewDisease continuumRF/RHDDiseaseFeverGlobal eradicationInfectious diseasesRheumatism
2021
The prospective randomized trial of the optimal evaluation of cardiac symptoms and revascularization: Rationale and design of the PRECISE trial
Nanna MG, Vemulapalli S, Fordyce CB, Mark DB, Patel MR, Al-Khalidi HR, Kelsey M, Martinez B, Yow E, Mullen S, Stone GW, Ben-Yehuda O, Udelson JE, Rogers C, Douglas PS. The prospective randomized trial of the optimal evaluation of cardiac symptoms and revascularization: Rationale and design of the PRECISE trial. American Heart Journal 2021, 245: 136-148. PMID: 34953768, PMCID: PMC8979644, DOI: 10.1016/j.ahj.2021.12.004.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseStable chest painChest painDiagnostic strategiesUsual careCardiac symptomsMajor adverse cardiac eventsNon-acute chest painObstructive coronary artery diseaseInitial diagnostic strategyInvasive cardiac catheterizationUse of CCTAUsual care strategyAdverse cardiac eventsProspective randomized trialsClinical care teamFractional flow reserveQuality of lifeHealth care costsOptimal evaluationPrimary endpointRevascularization TrialSecondary endpointsCardiac eventsArtery diseaseMulticomponent Strategy with Decentralized Molecular Testing for Tuberculosis
Cattamanchi A, Reza T, Nalugwa T, Adams K, Nantale M, Oyuku D, Nabwire S, Babirye D, Turyahabwe S, Tucker A, Sohn H, Ferguson O, Thompson R, Shete P, Handley M, Ackerman S, Joloba M, Moore D, Davis J, Dowdy D, Fielding K, Katamba A. Multicomponent Strategy with Decentralized Molecular Testing for Tuberculosis. New England Journal Of Medicine 2021, 385: 2441-2450. PMID: 34936740, PMCID: PMC9212879, DOI: 10.1056/nejmoa2105470.Peer-Reviewed Original ResearchConceptsSame-day treatmentSame-day diagnosisHealth centersMolecular testingTuberculosis testingHuman immunodeficiency virus (HIV) infectionDiagnostic strategiesImmunodeficiency virus infectionCommunity health centersCluster-randomized trialTreatment of tuberculosisSecondary outcomesMore patientsPrimary outcomePrompt diagnosisRoutine careEligible adultsIntervention groupIntervention periodHigh burdenVirus infectionIntervention centersControl groupPatientsTuberculosisThe immunologic response to severe acute respiratory syndrome coronavirus 2.
Le N, Kaman K, Martin H, Mullur J, Stenehjem K, Coomar L, Bahar B, Dutta M, Izurieta R, Brooks J. The immunologic response to severe acute respiratory syndrome coronavirus 2. Allergy & Asthma Proceedings 2021, 42: 495-505. PMID: 34871157, DOI: 10.2500/aap.2021.42.210077.Peer-Reviewed Original ResearchConceptsHuman immune systemImmune systemAdaptive immune responses to SARS-CoV-2 infectionSARS-CoV-2Immune response to SARS-CoV-2 infectionResponse to SARS-CoV-2 infectionSARS-CoV-2 infectionEnglish-language articlesInnate immune systemCourse of infectionInflammatory overreactionInnate immune pathwaysProportion of infectionsSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Immune modulationProphylactic interventionsRespiratory syndrome coronavirus 2Diagnostic strategiesImmunological responsePreventing severe diseaseSevere diseaseSyndrome coronavirus 2Immune pathwaysPatient recovery
2019
Serum MicroRNA Biomarkers Regulated by Simvastatin in a Primate Model of Endometriosis
Cosar E, Mamillapalli R, Moridi I, Duleba A, Taylor HS. Serum MicroRNA Biomarkers Regulated by Simvastatin in a Primate Model of Endometriosis. Reproductive Sciences 2019, 26: 1343-1350. PMID: 29587611, PMCID: PMC6949973, DOI: 10.1177/1933719118765971.Peer-Reviewed Original ResearchConceptsEndometriosis groupPrimate modelSerum microRNA BiomarkersReproductive-aged womenSerum miRNA expressionTreatment of endometriosisNoninvasive diagnostic strategyMiR-150-5pNonhuman primate modelEstrogen-dependent diseaseReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionTime polymerase chain reactionEndometriosis treatmentEndometriosis severitySimvastatin treatmentHuman endometriosisEndometriosisAccurate biomarkersHuman patientsMiR-451aControl expression levelsDiagnostic strategiesSpecific biomarkersSerum samplesRapid, point-of-care diagnosis of tuberculosis with novel Truenat assay: Cost-effectiveness analysis for India’s public sector
Lee DJ, Kumarasamy N, Resch SC, Sivaramakrishnan GN, Mayer KH, Tripathy S, Paltiel AD, Freedberg KA, Reddy KP. Rapid, point-of-care diagnosis of tuberculosis with novel Truenat assay: Cost-effectiveness analysis for India’s public sector. PLOS ONE 2019, 14: e0218890. PMID: 31265470, PMCID: PMC6605662, DOI: 10.1371/journal.pone.0218890.Peer-Reviewed Original ResearchConceptsIncremental cost-effectiveness ratioLife expectancySmear microscopyXpert MTB/RIFHIV-negative adultsPeripheral healthcare settingsMTB/RIFPrimary healthcare facilitiesSputum smear microscopyCost-effectiveness ratioCost-effectiveness analysisPresumptive tuberculosisTB diagnosisTB prevalenceTruenatMicroscopy centresXpertBudget impactRifampicin resistanceDiagnostic strategiesTuberculosisTB detectionHealthcare settingsDiagnostic sensitivityNovel molecular assay
2018
American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism
Lim W, Le Gal G, Bates S, Righini M, Haramati L, Lang E, Kline J, Chasteen S, Snyder M, Patel P, Bhatt M, Patel P, Braun C, Begum H, Wiercioch W, Schünemann H, Mustafa R. American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism. Blood Advances 2018, 2: 3226-3256. PMID: 30482764, PMCID: PMC6258916, DOI: 10.1182/bloodadvances.2018024828.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDeep vein thrombosisRecurrent venous thromboembolismExtremity deep vein thrombosisVenous thromboembolismPulmonary embolismVTE riskUpper extremity deep vein thrombosisLower extremity deep vein thrombosisMcMaster University GRADE CentreDiagnostic strategiesHematology 2018 guidelinesHigh VTE riskLower VTE riskPretest probability assessmentTomography pulmonary angiographyVentilation-perfusion scanningClinical decision ruleEvidence-based guidelinesNew diagnostic modalitiesHealth care professionalsAmerican SocietyModern diagnostic strategiesVTE diagnosisVTE prevalenceRecommendations Assessment2000. Rapid, Point-of-care Diagnosis of Tuberculosis with Novel Truenat Assay: Cost-Effectiveness and Budgetary Impact Analysis for India’s Public Sector
Lee D, Kumarasamy N, Resch S, Sivaramakrishnan G, Mayer K, Tripathy S, Paltiel A, Freedberg K, Reddy K. 2000. Rapid, Point-of-care Diagnosis of Tuberculosis with Novel Truenat Assay: Cost-Effectiveness and Budgetary Impact Analysis for India’s Public Sector. Open Forum Infectious Diseases 2018, 5: s582-s582. PMCID: PMC6254532, DOI: 10.1093/ofid/ofy210.1656.Peer-Reviewed Original ResearchIncremental cost-effectiveness ratioPublic healthcare facilitiesLife expectancyXpert MTB/RIFHIV-negative patientsPeripheral healthcare settingsHealthcare facilitiesBudgetary impact analysisMTB/RIFDiagnostic test costsSputum smear microscopyCost-effectiveness ratioMulti-way sensitivity analysesTB outcomesTB diagnosisPoint of careTruenatSmear microscopyXpertBudget impactTuberculosis diagnosticsDiagnostic strategiesHealthcare expendituresHealthcare settingsRifampin resistance
2015
Comparative Effectiveness Research: Alternatives to “Traditional” Computed Tomography Use in the Acute Care Setting
Moore CL, Broder J, Gunn ML, Bhargavan‐Chatfield M, Cody D, Cullison K, Daniels B, Gans B, Hall M, Gaines BA, Goldman S, Heil J, Liu R, Marin JR, Melnick ER, Novelline RA, Pare J, Repplinger MD, Taylor RA, Sodickson AD. Comparative Effectiveness Research: Alternatives to “Traditional” Computed Tomography Use in the Acute Care Setting. Academic Emergency Medicine 2015, 22: 1465-1473. PMID: 26576033, DOI: 10.1111/acem.12831.Peer-Reviewed Original ResearchConceptsAcute care settingCare settingsComputed tomography (CT) useCare of patientsAlternative diagnostic strategiesComputed tomography scanningEssential diagnostic toolTomography useCT useEmergency physiciansEmergency radiologistsComparative effectivenessTomography scanningDiagnostic strategiesDiagnostic toolDelphi techniqueSettingPatientsMedical physicistsPhysiciansCareCTThe Clinical Utility of a Novel Blood-Based Multi-Transcriptome Assay for the Diagnosis of Neuroendocrine Tumors of the Gastrointestinal Tract
Modlin I, Kidd M, Bodei L, Drozdov I, Aslanian H. The Clinical Utility of a Novel Blood-Based Multi-Transcriptome Assay for the Diagnosis of Neuroendocrine Tumors of the Gastrointestinal Tract. The American Journal Of Gastroenterology 2015, 110: 1223. PMID: 26032155, DOI: 10.1038/ajg.2015.160.Peer-Reviewed Original ResearchConceptsPancreatic neuroendocrine tumorsNeuroendocrine tumorsCgA measurementMalignant gastrointestinal diseasesBlood-based biomarkersNeuroendocrine tumor diseaseExtensive diseaseIntestinal carcinoidsColorectal cancerGastrointestinal diseasesCgA levelsPancreatic diseaseClinical utilityGastrointestinal tractDiagnostic strategiesNETestDiseaseTumorsNETest scoreTumor diseaseNovel bloodNational InstituteDiagnosisBiomarkersCgAFulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma
Abegunde A, Aisien E, Mba B, Chennuri R, Sekosan M. Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma. Case Reports In Gastrointestinal Medicine 2015, 2015: 869746. PMID: 25815217, PMCID: PMC4359886, DOI: 10.1155/2015/869746.Peer-Reviewed Original ResearchPrimary hepatic angiosarcomaHepatic angiosarcomaHepatic failureRapidity of progressionFulminant hepatic failureOnset of symptomsLimited treatment optionsEarly diagnostic strategiesReview of literatureNonspecific symptomsHealthy menTreatment optionsAggressive tumorsCase reportNew therapiesAngiosarcomaAdvanced stageDiagnostic strategiesTwo monthsSymptomsJaundicePatientsFailurePrognosisMalignancy
2014
Modeling of Novel Diagnostic Strategies for Active Tuberculosis – A Systematic Review: Current Practices and Recommendations
Zwerling A, White RG, Vassall A, Cohen T, Dowdy DW, Houben RM. Modeling of Novel Diagnostic Strategies for Active Tuberculosis – A Systematic Review: Current Practices and Recommendations. PLOS ONE 2014, 9: e110558. PMID: 25340701, PMCID: PMC4207742, DOI: 10.1371/journal.pone.0110558.Peer-Reviewed Original ResearchConceptsNucleic acid amplification testsIncremental cost-effectiveness ratioActive tuberculosisHealth system modelDiagnostic strategiesNovel diagnostic strategiesAlternative nucleic acid amplification testsXpert MTB/RIFMTB/RIFCost-effectiveness ratioMulti-way sensitivity analysesFalse-negative diagnosesPre-diagnostic periodCost-effectiveness modelCost-effectiveness estimatesDiagnostic delayDiagnostic pathwayAdditional epidemiological dataTB diagnosticsEpidemiological dataReference listsAmplification testsEpidemiological impactEligible papersEpidemiological settingsPROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial
Douglas PS, Hoffmann U, Lee KL, Mark DB, Al-Khalidi HR, Anstrom K, Dolor RJ, Kosinski A, Krucoff MW, Mudrick DW, Patel MR, Picard MH, Udelson JE, Velazquez EJ, Cooper L, investigators P. PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial. American Heart Journal 2014, 167: 796-803.e1. PMID: 24890527, PMCID: PMC4044617, DOI: 10.1016/j.ahj.2014.03.003.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePROMISE trialAnatomical testingProspective Multicenter Imaging StudyDiagnostic strategiesInitial diagnostic strategyMajor procedural complicationsSubsequent care decisionsComposite of deathPrimary end pointLarge pragmatic trialClinical care teamQuality of lifeDiagnostic testing strategiesMultidetector coronaryChest painSymptomatic patientsUnstable anginaArtery diseaseProcedural complicationsRandomized trialsSymptomatic subjectsClinical effectivenessMyocardial infarctionPragmatic trial
2011
A modelling framework to support the selection and implementation of new tuberculosis diagnostic tools [State of the art series. Operational research. Number 8 in the series]
Lin HH, Langley I, Mwenda R, Doulla B, Egwaga S, Millington KA, Mann GH, Murray M, Squire SB, Cohen T. A modelling framework to support the selection and implementation of new tuberculosis diagnostic tools [State of the art series. Operational research. Number 8 in the series]. The International Journal Of Tuberculosis And Lung Disease 2011, 15: 996-1004. PMID: 21740663, DOI: 10.5588/ijtld.11.0062.Peer-Reviewed Original ResearchConceptsDiagnostic strategiesHealth systemTB transmission dynamicsDiagnosis of tuberculosisHealth system requirementsDiagnostic toolHealth system componentsPolicy makersNew diagnostic strategiesHealth care infrastructureNovel diagnostic toolPatient outcomesDifferent epidemiologyJoint modelling frameworkModelling frameworkTest characteristicsCare infrastructureTransmission dynamicsRational choiceTuberculosisTechnological innovationStrategy decisionsDifficult decisionsMakersRecent introduction
2010
Radiation Exposure From Medical Imaging in Patients With Chronic and Recurrent Conditions
Stein E, Haramati L, Bellin E, Ashton L, Mitsopoulos G, Schoenfeld A, Amis E. Radiation Exposure From Medical Imaging in Patients With Chronic and Recurrent Conditions. Journal Of The American College Of Radiology 2010, 7: 351-359. PMID: 20439078, DOI: 10.1016/j.jacr.2009.12.015.Peer-Reviewed Original ResearchConceptsPulmonary thromboembolic diseaseRenal colicThromboembolic diseaseCardiac diseaseTotal effective dosesRadiation exposureRecurrent conditionEffective dosesProportion of patientsMedical radiation exposureCumulative radiation dosesOrgan-specific dosesRadiation dosesTotal effective doseDiagnostic cohortIndividual patientsPatientsHydrocephalusDiagnostic strategiesEffective doseDiseaseChronicColicDosesCohort
2007
ITGCN of the Testis, Contralateral Testicular Biopsy and Bilateral Testicular Cancer
Karellas M, Damjanov I, Holzbeierlein J. ITGCN of the Testis, Contralateral Testicular Biopsy and Bilateral Testicular Cancer. Urologic Clinics Of North America 2007, 34: 119-125. PMID: 17484917, DOI: 10.1016/j.ucl.2007.02.015.Peer-Reviewed Original ResearchConceptsContralateral testicular biopsyTesticular tumorsTesticular biopsyIntratubular germ cell neoplasiaTesticular germ cell tumorsBilateral testicular cancerBilateral testicular tumorsGerm cell tumorsGerm cell neoplasiaNoninvasive precursor lesionsTreatment optionsTesticular cancerCell tumorsPrecursor lesionsCell neoplasiaMalignant transformationDiagnostic strategiesTumorsMolecular changesBiopsyNeoplasiaSkakkebaekLesionsCancerIncidencePhysiology and Pathophysiology of the Parathyroid Glands and Preoperative Evaluation
Holt E, Inzucchi S. Physiology and Pathophysiology of the Parathyroid Glands and Preoperative Evaluation. 2007, 235-243. DOI: 10.1007/978-3-540-68043-7_19.Peer-Reviewed Original ResearchCommon endocrine conditionExtracellular calcium concentrationComplex hormonal systemPrimary hyperparathyroidismSevere sequelaeChronic hypercalcemiaPreoperative evaluationSurgical indicationsClinical featuresCalcium metabolismParathyroid glandsEndocrine conditionsDiagnostic strategiesHormonal systemsCalcium concentrationCommon aberrationsFrequent explanationHypercalcemiaHyperparathyroidismSequelaeOsteoporosisNephrolithiasisPathophysiologySymptomsDisease
2006
Gastrointestinal Carcinoids: The Evolution of Diagnostic Strategies
Modlin IM, Latich I, Zikusoka M, Kidd M, Eick G, Chan AK. Gastrointestinal Carcinoids: The Evolution of Diagnostic Strategies. Journal Of Clinical Gastroenterology 2006, 40: 572-582. PMID: 16917396, DOI: 10.1097/00004836-200608000-00003.Peer-Reviewed Original Research
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