2025
TYPE OF SUBMUCOSAL INJECTION FOR ENDOSCOPIC RESECTION OF LARGE COLON POLYPS - RESULTS OF A RANDOMIZED TRIAL
Pohl H, Rex D, Barber J, Moyer M, Elmunzer B, Rastogi A, Gordon S, Zolotarevsky E, Levenick J, Aslanian H, Elatrache M, Von Renteln D, Wallace M, Brahmbhatt B, Keswani R, Kumta N, Pleskow D, Smith Z, Ghanimeh M, Simmer S, Sanaei O, Yang Z, Mackenzie T, Piraka C. TYPE OF SUBMUCOSAL INJECTION FOR ENDOSCOPIC RESECTION OF LARGE COLON POLYPS - RESULTS OF A RANDOMIZED TRIAL. Gastrointestinal Endoscopy 2025, 101: s285-s286. DOI: 10.1016/j.gie.2025.03.503.Peer-Reviewed Original ResearchCOMPARABLE LONG-TERM EFFICACY OF COLD AND HOT EMR OF LARGE COLON POLYPS - FOLLOW UP RESULTS OF A RANDOMIZED TRIAL
Pohl H, Rex D, Barber J, Rastogi A, Moyer M, Levenick J, Von Renteln D, Gordon S, Aslanian H, Elatrache M, Wallace M, Elmunzer B, Keswani R, Kumta N, Pleskow D, Tonzi E, Mackenzie T, Piraka C. COMPARABLE LONG-TERM EFFICACY OF COLD AND HOT EMR OF LARGE COLON POLYPS - FOLLOW UP RESULTS OF A RANDOMIZED TRIAL. Gastrointestinal Endoscopy 2025, 101: s270-s271. DOI: 10.1016/j.gie.2025.03.480.Peer-Reviewed Original ResearchColonic polypsRandomized trials
2021
S332 Determining the Profile of Patients Lost in Follow-up After the Resection of High-Risk Colonic Polyps
Jove A, Cifuentes J, Berger S, Caskey K, Kim H, Gacha M, Jarbrink-Sehgal M, Velez M, Hair C, Sealock R, Ketwaroo G. S332 Determining the Profile of Patients Lost in Follow-up After the Resection of High-Risk Colonic Polyps. The American Journal Of Gastroenterology 2021, 116: s144-s144. DOI: 10.14309/01.ajg.0000773800.52079.e4.Peer-Reviewed Original ResearchEffects of Somatic Methylation in Colonic Polyps on Risk of Developing Metachronous Advanced Colorectal Lesions
Murcia O, Martínez-Roca A, Juárez M, Giner-Calabuig M, Alustiza M, Mira C, Mangas-Sanjuan C, Serrano E, Ruiz-Gómez FA, Baile-Maxia S, Medina L, Alenda C, Payá A, Rodriguez-Soler M, Zapater P, Jover R. Effects of Somatic Methylation in Colonic Polyps on Risk of Developing Metachronous Advanced Colorectal Lesions. Cancers 2021, 13: 246. PMID: 33440809, PMCID: PMC7827613, DOI: 10.3390/cancers13020246.Peer-Reviewed Original ResearchCpG island methylator phenotypeAdvanced colorectal lesionsColorectal lesionsColonic polypsRetrospective cohort studyHigh-grade dysplasiaNegative predictive valueBaseline colonoscopyCohort studyConsecutive patientsEndoscopic surveillancePathological characteristicsVillous componentSerrated lesionsPredictive valuePatientsUseful markerSomatic hypermethylationPolyp sizePolypsLesionsMethylator phenotypeSomatic methylationDysplasiaRisk
2020
Increased Th17-Related Cytokine Serum Levels in Patients With Multiple Polyps of Unexplained Origin
Alustiza M, Hernández-Illán E, Juárez M, Giner-Calabuig M, Mira C, Martínez-Roca A, Bujanda L, Rodríguez-Moranta F, Cubiella J, de-Castro L, Marín-Gabriel JC, Herreros-de-Tejada A, Fernández-Bañares F, Nicolás-Pérez D, Giménez P, Martínez-Cardona C, Francés R, Murcia O, Jover R. Increased Th17-Related Cytokine Serum Levels in Patients With Multiple Polyps of Unexplained Origin. Clinical And Translational Gastroenterology 2020, 11: e00143. PMID: 32352715, PMCID: PMC7145049, DOI: 10.14309/ctg.0000000000000143.Peer-Reviewed Original ResearchConceptsC-reactive proteinMultiple colonic polypsCytokine serum levelsIL-17AIL-6IL-4IL-2Colonic polypsIL-23Serum levelsMultiple polypsHigh-sensitivity enzyme-linked immunosorbentSerum/bloodControl peopleEnzyme-linked immunosorbentLevels of glucoseCytokine levelsMost patientsNormal colonoscopyTh17 cellsBasal insulinIL-10Smoking habitsInflammatory cytokinesImmune response
2017
KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia
Juárez M, Egoavil C, Rodríguez-Soler M, Hernández-Illán E, Guarinos C, García-Martínez A, Alenda C, Giner-Calabuig M, Murcia O, Mangas C, Payá A, Aparicio JR, Ruiz FA, Martínez J, Casellas JA, Soto JL, Zapater P, Jover R. KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia. PLOS ONE 2017, 12: e0184937. PMID: 28953955, PMCID: PMC5617162, DOI: 10.1371/journal.pone.0184937.Peer-Reviewed Original ResearchConceptsAdvanced adenomasKRAS mutationsColonic polypsAdvanced neoplasiaAdvanced polypsMetachronous advanced neoplasiaHigh-grade dysplasiaSomatic KRAS mutationsBRAF somatic mutationsMetachronous neoplasiaSurveillance colonoscopyPathologic characteristicsSplenic flexureGrade dysplasiaVillous componentUnivariate analysisSerrated polypsRisk featuresSomatic BRAFMultivariate analysisAdenomasAbstractTextPolypsPatientsNeoplasia
2015
Cold Snare Polypectomy for Large Sessile Colonic Polyps: A Single‐Center Experience
Muniraj T, Sahakian A, Ciarleglio MM, Deng Y, Aslanian HR. Cold Snare Polypectomy for Large Sessile Colonic Polyps: A Single‐Center Experience. Gastroenterology Research And Practice 2015, 2015: 175959. PMID: 25878658, PMCID: PMC4387686, DOI: 10.1155/2015/175959.Peer-Reviewed Original ResearchCold snare polypectomySnare polypectomySessile polypsLarge sessile colonic polypsSingle-center experienceFurther prospective studiesLarge sessile polypsLarger patient groupsSessile colonic polypsAdverse eventsPostpolypectomy bleedingComplication rateConventional polypectomyFavorable efficacyColonoscopic polypectomyPatient groupProspective studyColorectal cancerResidual polypProcedure timePolypectomyLarge polypsColonic polypsSmall polypsPolyps
2012
Optic pathway glioma as part of a constitutional mismatch‐repair deficiency syndrome in a patient meeting the criteria for neurofibromatosis type 1
Yeung JT, Pollack IF, Shah S, Jaffe R, Nikiforova M, Jakacki RI. Optic pathway glioma as part of a constitutional mismatch‐repair deficiency syndrome in a patient meeting the criteria for neurofibromatosis type 1. Pediatric Blood & Cancer 2012, 60: 137-139. PMID: 22848017, DOI: 10.1002/pbc.24254.Peer-Reviewed Original ResearchConceptsOptic pathway gliomasNeurofibromatosis type 1NF-1Constitutional mismatch repair deficiency syndromeType 1Multiple colonic polypsBi-allelic lossMismatch repair genesConstitutional mismatchCommon manifestationDeficiency syndromeLait spotsDiagnostic criteriaBone marrowColonic polypsHigher likelihoodAffected individualsPatientsPhenotypic featuresRepair genesGliomasBiallelic deletionBowelMalignancySyndrome
2011
MUC Expression in Hyperplastic and Serrated Colonic Polyps
Gibson JA, Hahn HP, Shahsafaei A, Odze RD. MUC Expression in Hyperplastic and Serrated Colonic Polyps. The American Journal Of Surgical Pathology 2011, 35: 742-749. PMID: 21490447, DOI: 10.1097/pas.0b013e31821537a2.Peer-Reviewed Original ResearchConceptsSSA/PExpression of MUC6Hyperplastic polypsSerrated polypsSSA/PsPolyp groupRight colonMUC expressionColonic polypsSerrated colonic polypsSessile serrated adenomas/polypsSerrated adenomas/polypsTraditional serrated adenomasGoblet cell typeProgression of malignancyAdenomas/polypsIntensity of stainingDifferent anatomic locationsMicrovesicular typeSerrated carcinogenesisDifferential diagnosisMUC6 expressionAnatomic locationSerrated pathwaySerrated adenomas
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