2024
An Updated Simplified Severity Scale for Age-Related Macular Degeneration Incorporating Reticular Pseudodrusen Age-Related Eye Disease Study Report Number 42
Agrón E, Domalpally A, Chen Q, Lu Z, Chew E, Keenan T, Groups A. An Updated Simplified Severity Scale for Age-Related Macular Degeneration Incorporating Reticular Pseudodrusen Age-Related Eye Disease Study Report Number 42. Ophthalmology 2024, 131: 1164-1174. PMID: 38657840, PMCID: PMC11416341, DOI: 10.1016/j.ophtha.2024.04.011.Peer-Reviewed Original ResearchAge-related eye disease studyProgression to late AMDReticular pseudodrusenLate AMDFive-year ratesProgression rateAge-related macular degenerationSeverity ScaleEye Disease StudyClinical trial cohortIncrease prognostic accuracyPost Hoc AnalysisMacular degenerationAREDS2Prognostic accuracyTrial cohortRisk featuresHoc AnalysisRisk categorizationPseudodrusenAge-relatedBaselineDisease StudyRiskExternal validation
2023
Post-operative PET/CT improves the detection of early recurrence of squamous cell carcinomas of the oral cavity
Yu Y, Schöder H, Zakeri K, Chen L, Kang J, McBride S, Tsai C, Gelblum D, Boyle J, Cracchiolo J, Cohen M, Singh B, Ganly I, Patel S, Michel L, Dunn L, Sherman E, Pfister D, Wong R, Riaz N, Lee N. Post-operative PET/CT improves the detection of early recurrence of squamous cell carcinomas of the oral cavity. Oral Oncology 2023, 141: 106400. PMID: 37099979, PMCID: PMC10631462, DOI: 10.1016/j.oraloncology.2023.106400.Peer-Reviewed Original ResearchConceptsOral squamous cell carcinomaIntermediate-risk featuresPET/CTHigh-risk featuresPost-operative radiationSquamous cell carcinomaEarly recurrenceRisk featuresSurgical marginsCell carcinomaPET/CT planningAddition of chemotherapyClose surgical marginsDisease-free survivalPositive surgical marginsRecords of patientsPositron emission tomographyTreatment intensificationBaseline characteristicsNode positivityLymphovascular invasionOverall survivalPT3-4Perineural invasionTumor thickness
2021
The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program bariatric surgical risk/benefit calculator: 30-day risk
Grieco A, Huffman KM, Cohen ME, Hall BL, Morton JM, Ko CY. The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program bariatric surgical risk/benefit calculator: 30-day risk. Surgery For Obesity And Related Diseases 2021, 17: 1117-1124. PMID: 33773930, DOI: 10.1016/j.soard.2021.02.005.Peer-Reviewed Original ResearchConceptsBariatric Surgery AccreditationLaparoscopic adjustable gastric bandCo-morbidity remissionLaparoscopic sleeve gastrectomyAdjustable gastric bandSurgical care teamQuality Improvement ProgramLogistic regression modelsClinical data registryMBSAQIP dataLaparoscopic RouxBariatric surgeryBiliopancreatic diversionGastric bandGastric bypassSleeve gastrectomyAdult patientsDuodenal switchPostoperative riskRisk calculatorCare teamAmerican CollegeData registryExcellent calibrationRisk features
2019
Adverse Histologic Features in Colorectal Nonpedunculated Malignant Polyps With Nodal Metastasis
Patel N, Vyas M, Celli R, Jain D, Zhang X. Adverse Histologic Features in Colorectal Nonpedunculated Malignant Polyps With Nodal Metastasis. The American Journal Of Surgical Pathology 2019, 44: 241-246. PMID: 31498179, DOI: 10.1097/pas.0000000000001369.Peer-Reviewed Original ResearchConceptsHigh-grade tumor buddingAdverse histologic featuresMalignant polypsNodal metastasisTumor buddingHistologic featuresLymphovascular invasionNode metastasisLymph node metastatic potentialMargin statusSubsequent resectionColectomy specimenColectomy proceduresDifferentiated clustersTumor differentiationOdds ratioRisk featuresMetastasisMetastatic potentialPiecemeal polypectomyPolypsRiskInvasionColectomyResection
2017
KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia
Juárez M, Egoavil C, Rodríguez-Soler M, Hernández-Illán E, Guarinos C, García-Martínez A, Alenda C, Giner-Calabuig M, Murcia O, Mangas C, Payá A, Aparicio JR, Ruiz FA, Martínez J, Casellas JA, Soto JL, Zapater P, Jover R. KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia. PLOS ONE 2017, 12: e0184937. PMID: 28953955, PMCID: PMC5617162, DOI: 10.1371/journal.pone.0184937.Peer-Reviewed Original ResearchConceptsAdvanced adenomasKRAS mutationsColonic polypsAdvanced neoplasiaAdvanced polypsMetachronous advanced neoplasiaHigh-grade dysplasiaSomatic KRAS mutationsBRAF somatic mutationsMetachronous neoplasiaSurveillance colonoscopyPathologic characteristicsSplenic flexureGrade dysplasiaVillous componentUnivariate analysisSerrated polypsRisk featuresSomatic BRAFMultivariate analysisAdenomasAbstractTextPolypsPatientsNeoplasiaRetinoblastoma: A Sixteen-Year Review of the Presentation, Treatment, and Outcome from a Tertiary Care Institute in Northern India
Singh U, Katoch D, Kaur S, Dogra M, Bansal D, Kapoor R. Retinoblastoma: A Sixteen-Year Review of the Presentation, Treatment, and Outcome from a Tertiary Care Institute in Northern India. Ocular Oncology And Pathology 2017, 4: 23-32. PMID: 29344495, PMCID: PMC5757564, DOI: 10.1159/000477408.Peer-Reviewed Original ResearchRetinoblastoma patientsHistopathological high-risk featuresHistopathological risk factorsHigh-risk featuresTertiary care institutionRate of metastasisDefaulted therapyExtraocular extensionIntraocular diseasePrimary enucleationLocal recurrenceAdvanced diseaseRetrospective reviewPediatric patientsClinical characteristicsPrimary treatmentChemoreductionRisk featuresPatientsRisk factorsTherapy refusalStudy epidemiologyRetinoblastomaEnucleationMetastasis
2011
Inherited Variants in the Chemokine CCL2 Gene and Prostate Cancer Aggressiveness in a Caucasian Cohort
Sun T, Mary L, Oh W, Freedman M, Pomerantz M, Pienta K, Kantoff P. Inherited Variants in the Chemokine CCL2 Gene and Prostate Cancer Aggressiveness in a Caucasian Cohort. Clinical Cancer Research 2011, 17: 1546-1552. PMID: 21135144, PMCID: PMC3060307, DOI: 10.1158/1078-0432.ccr-10-2015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAllelesChemokine CCL2Cohort StudiesDisease ProgressionGenetic Predisposition to DiseaseGenetic VariationGenotypeHaplotypesHumansLinkage DisequilibriumMaleMiddle AgedNeoplasm InvasivenessNeoplasm MetastasisPolymorphism, Single NucleotideProstatectomyProstatic NeoplasmsRiskConceptsC-C chemokine ligand 2Prostate cancer aggressivenessSingle nucleotide polymorphismsCancer aggressivenessMarkers of disease aggressivenessAssociated with advanced pathological stageBiopsy Gleason scoreGood-risk featuresProstate cancer developmentProstate cancer progressionAdvanced pathological stageChemokine ligand 2Associated with markersProstate cancer tumorigenesisGleason scoreRadical prostatectomyClinicopathological variablesPathological stageDisease aggressivenessPatient cohortG alleleGermline variantsCaucasian cohortProstateRisk features
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