2018
Clinical, Histologic, and Immunophenotypic Features of Serrated Polyps in Patients With Inflammatory Bowel Disease
Yang C, Tarabishy Y, Dassopoulos T, Nalbantoglu I. Clinical, Histologic, and Immunophenotypic Features of Serrated Polyps in Patients With Inflammatory Bowel Disease. Gastroenterology Research 2018, 11: 355-360. PMID: 30344807, PMCID: PMC6188039, DOI: 10.14740/gr1064w.Peer-Reviewed Original ResearchInflammatory bowel diseaseSSA/PsHyperplastic polypsSerrated polypsBowel diseaseSporadic serrated polypsLow-grade dysplasiaSessile serrated adenomas/polypsSerrated adenomas/polypsImmunohistochemistry staining patternsTraditional serrated adenomasSite-matched controlsColorectal serrated polypsAdenomas/polypsSporadic colorectal carcinomasOlder patientsClinicopathologic featuresImmunophenotypical featuresImmunophenotypic featuresColorectal carcinomaStudy groupPatientsSerrated adenomasStaining patternPolyps
2016
Over-the-scope clip-assisted endoscopic full-thickness resection of epithelial and subepithelial GI lesions
Al-Bawardy B, Rajan E, Wong Kee Song LM. Over-the-scope clip-assisted endoscopic full-thickness resection of epithelial and subepithelial GI lesions. Gastrointestinal Endoscopy 2016, 85: 1087-1092. PMID: 27569858, DOI: 10.1016/j.gie.2016.08.019.Peer-Reviewed Original ResearchConceptsEndoscopic full-thickness resectionConventional resection techniquesFull-thickness resectionAdverse eventsResection techniquesEpithelial lesionsHistopathologic diagnosisR0 resection statusMean lesion sizeSessile serrated adenomasR0 resectionEndoscopic findingsResection statusBloc resectionElectrosurgical snareRectosigmoid colonGI lesionsMean ageDefinitive diagnosisNeuroendocrine tumorsSubepithelial lesionsPancreatic heterotopiaSafe techniquePadlock clipSerrated adenomas
2015
Clinical, pathologic, and outcome study of hyperplastic and sessile serrated polyps in inflammatory bowel disease
Shen J, Gibson JA, Schulte S, Khurana H, Farraye FA, Levine J, Burakoff R, Cerda S, Qazi T, Hamilton M, Srivastava A, Odze RD. Clinical, pathologic, and outcome study of hyperplastic and sessile serrated polyps in inflammatory bowel disease. Human Pathology 2015, 46: 1548-1556. PMID: 26297256, DOI: 10.1016/j.humpath.2015.06.019.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseNeoplastic lesionsHyperplastic polypsFlat dysplasiaIBD patientsBowel diseaseAdenoma-like dysplasiaTraditional serrated adenomasSessile serrated polypsAverage followSurgical resectionClinicopathological featuresColon resectionSporadic adenomasSerrated polypsLower riskSerrated pathwayPatientsSerrated adenomasLesionsDysplasiaAdenoma/AdenocarcinomaResectionAdenomas
2011
Risk Factors for Sessile Serrated Adenomas
Anderson JC, Rangasamy P, Rustagi T, Myers M, Sanders M, Vaziri H, Wu G, Birk JW, Protiva P. Risk Factors for Sessile Serrated Adenomas. Journal Of Clinical Gastroenterology 2011, 45: 694-699. PMID: 21325950, DOI: 10.1097/mcg.0b013e318207f3cf.Peer-Reviewed Original ResearchConceptsColorectal cancerTubular adenomaDiabetes mellitusRisk factorsPack-year exposureUse of aspirinSessile serrated adenomasCRC screeningFamily historyPatientsSerrated adenomasAdenomasMultivariate analysisMolecular abnormalitiesSmokersMellitusSmokingLesionsGroupNonsmokersSet of controlsStatinsObesityAspirinImportant pathwayMUC Expression in Hyperplastic and Serrated Colonic Polyps
Gibson JA, Hahn HP, Shahsafaei A, Odze RD. MUC Expression in Hyperplastic and Serrated Colonic Polyps. The American Journal Of Surgical Pathology 2011, 35: 742-749. PMID: 21490447, DOI: 10.1097/pas.0b013e31821537a2.Peer-Reviewed Original ResearchConceptsSSA/PExpression of MUC6Hyperplastic polypsSerrated polypsSSA/PsPolyp groupRight colonMUC expressionColonic polypsSerrated colonic polypsSessile serrated adenomas/polypsSerrated adenomas/polypsTraditional serrated adenomasGoblet cell typeProgression of malignancyAdenomas/polypsIntensity of stainingDifferent anatomic locationsMicrovesicular typeSerrated carcinogenesisDifferential diagnosisMUC6 expressionAnatomic locationSerrated pathwaySerrated adenomasSessile serrated adenomas and classical adenomas: An epigenetic perspective on premalignant neoplastic lesions of the gastrointestinal tract
Dhir M, Yachida S, Van Neste L, Glöckner SC, Jeschke J, Pappou EP, Montgomery EA, Herman JG, Baylin SB, Iacobuzio‐Donahue C, Ahuja N. Sessile serrated adenomas and classical adenomas: An epigenetic perspective on premalignant neoplastic lesions of the gastrointestinal tract. International Journal Of Cancer 2011, 129: 1889-1898. PMID: 21154739, PMCID: PMC3206997, DOI: 10.1002/ijc.25847.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAdenomaAgedAged, 80 and overCDX2 Transcription FactorColonic PolypsCpG IslandsDiagnosis, DifferentialDNA MethylationFemaleGastrointestinal NeoplasmsGene Expression Regulation, NeoplasticHomeodomain ProteinsHumansHyperplasiaMaleMiddle AgedMutL Protein Homolog 1Nuclear ProteinsPrecancerous ConditionsProto-Oncogene ProteinsProto-Oncogene Proteins p21(ras)ras ProteinsToll-Like Receptor 2ConceptsSessile serrated adenomasHyperplastic polypsMethylation of CDX2Neoplastic lesionsGastrointestinal tractMultiplex methylation-specific PCRSerrated adenomasEarly detectionHIN-1Villous adenomaTubular adenomaClassical adenomasMethylation-specific PCRIRB approvalDiagnostic utilityAdenomasGastrointestinal adenomasHospital pathologyPremalignant adenomasAdenoma samplesCpG island methylation statusInterobserver variabilityTLR2DysplasiaLesions
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply