2025
Lifestyle behavioral weight‐loss treatment for binge‐eating disorder in patients with obesity: where's the harm?
Yurkow S, Ivezaj V, Grilo C. Lifestyle behavioral weight‐loss treatment for binge‐eating disorder in patients with obesity: where's the harm? Obesity 2025, 33: 1058-1066. PMID: 40342236, PMCID: PMC12119222, DOI: 10.1002/oby.24289.Peer-Reviewed Original ResearchConceptsBinge-eating disorderED psychopathologyWeight loss treatmentExacerbate eating disordersBinge-eating frequencyPsychopathology scoresBinge eatingSymptoms of binge eatingBehavioral weight loss treatmentIncreased symptomsEating DisordersPsychopathologyFollow-upDisordersPosttreatmentHeterogeneity of outcomesEatingSecondary analysisFrequency of casesCoexisting obesityClinical contextParticipantsIndividual levelBingeObesity
2024
Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder
Grilo C, Ivezaj V, Gueorguieva R. Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder. International Journal Of Eating Disorders 2024, 57: 1268-1273. PMID: 38321617, PMCID: PMC11093697, DOI: 10.1002/eat.24141.Peer-Reviewed Original ResearchOvervaluation of shape/weightEating-disorder psychopathologyBinge-eating disorderEating Disorder Examination interviewBeck Depression InventoryWeight loss treatmentClinical overvaluationBinge-eating frequencyDiagnostic specifierBinge eatingNon-abstinenceExamination interviewDepression InventoryShape/weightDepression scoresFollow-upPsychopathologyAbstinenceBingeDepressionClinical implicationsDepression 1PosttreatmentDisordersOvervaluation
2023
Improvements in cardiovascular disease risk factors associated with modest weight loss following treatment in patients with binge‐eating disorder and obesity
Yurkow S, Ivezaj V, Grilo C. Improvements in cardiovascular disease risk factors associated with modest weight loss following treatment in patients with binge‐eating disorder and obesity. International Journal Of Eating Disorders 2023, 56: 2074-2083. PMID: 37530200, PMCID: PMC10834830, DOI: 10.1002/eat.24035.Peer-Reviewed Original ResearchConceptsCardiovascular disease risk factorsModest weight lossDisease risk factorsBinge-eating disorderPlasma glucoseRisk factorsWeight lossLifestyle changesBehavioral lifestyle changesCardiovascular disease riskWeight loss treatmentSignificant improvementRelated lifestyle changesTotal cholesterolPotential health benefitsHeart ratePatientsObesityDisease riskHbA1cHealth benefitsDisordersTriglyceridesTreatmentPosttreatmentPredictors and significance of rapid response to behaviorally based treatment of binge eating disorder
Yurkow S, Ivezaj V, Grilo C. Predictors and significance of rapid response to behaviorally based treatment of binge eating disorder. Obesity 2023, 31: 390-398. PMID: 36623872, PMCID: PMC9877118, DOI: 10.1002/oby.23648.Peer-Reviewed Original ResearchConceptsDemographic featuresTreatment attitudesWeight lossFourth treatment weekWeight loss outcomesPsychiatric variablesSuperior clinical outcomesWeight loss treatmentTreatment of bingeClinical severity variablesClinical outcomesPrognostic significanceTreatment weekClinical trialsBaseline predictorsLoss outcomesLoss treatmentPosttreatment outcomesBinge eatingIndependent assessorsBingeSeverity variablesDisordersPatientsTreatment
2022
Dietary adaptation for weight loss maintenance at Yale (DAWLY): Protocol and predictions for a randomized controlled trial
Fang X, Davis X, Flack KD, Duncan C, Li F, White M, Grilo C, Small DM. Dietary adaptation for weight loss maintenance at Yale (DAWLY): Protocol and predictions for a randomized controlled trial. Frontiers In Nutrition 2022, 9: 940064. PMID: 35967820, PMCID: PMC9369668, DOI: 10.3389/fnut.2022.940064.Peer-Reviewed Original ResearchWeight loss maintenanceHigh-fat dietWeight loss treatmentLoss maintenanceWeight lossLoss treatmentStandard behavioral weight loss treatmentShort-term weight lossBehavioral weight loss interventionBehavioral weight loss treatmentGut-brain pathwaysPlacebo-controlled trialGut-brain axisVagal afferent pathwaysGut-brain signalingDietary fat intakeOverweight/obesityWeight loss interventionPrecision medicine approachEnergy-dense foodsLoss interventionFat intakeAfferent pathwaysHabitual intakeMetabolic health
2021
Real-time fluctuations in mindful awareness, willingness, and values clarity, and their associations with craving and dietary lapse among those seeking weight loss
Sala M, Roos CR, Crochiere RJ, Butryn ML, Juarascio AS, Manasse SM, Forman EM. Real-time fluctuations in mindful awareness, willingness, and values clarity, and their associations with craving and dietary lapse among those seeking weight loss. Journal Of Contextual Behavioral Science 2021, 22: 87-92. PMID: 34900572, PMCID: PMC8653958, DOI: 10.1016/j.jcbs.2021.10.002.Peer-Reviewed Original ResearchPhysical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder
Grilo CM, Kerrigan SG, Lydecker JA, White MA. Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder. Obesity 2021, 29: 2026-2034. PMID: 34582624, PMCID: PMC8612949, DOI: 10.1002/oby.23278.Peer-Reviewed Original ResearchConceptsBehavioral weight loss treatmentWeight loss treatmentLatinx patientsPhysical activity changesBWL treatmentReduced depressionCommunity mental health centerWeight lossPA changePlacebo-controlled trialAddition of orlistatMental health centersActivity changesPrognostic significanceMedication conditionHealth centersLoss treatmentPatientsObesitySecondary analysisClinical settingBed statusBaselineTreatmentDepression
2020
Examining Self-Weighing Behaviors and Associated Features and Treatment Outcomes in Patients with Binge-Eating Disorder and Obesity with and without Food Addiction
Wiedemann AA, Ivezaj V, Gueorguieva R, Potenza MN, Grilo CM. Examining Self-Weighing Behaviors and Associated Features and Treatment Outcomes in Patients with Binge-Eating Disorder and Obesity with and without Food Addiction. Nutrients 2020, 13: 29. PMID: 33374870, PMCID: PMC7823454, DOI: 10.3390/nu13010029.Peer-Reviewed Original ResearchConceptsBinge-eating disorderFood addictionFrequency of weighingShape/weightRelated perceptionsEating Disorder ExaminationBinge Eating DisorderBehavioral weight loss treatmentWeight loss treatmentDisorder ExaminationLess acceptanceFrequent weighingPoor treatment outcomesTreatment outcomesNegative reactionsBWL treatmentParticipantsLoss treatmentMixed effects modelsPerceptionFA statusAddictionAssociated featuresGreater likelihoodIndividuals
2019
Getting a head start: identifying pretreatment correlates associated with early weight loss for individuals participating in weight loss treatment
Wiedemann AA, Baumgardt SS, Ivezaj V, Kerrigan SG, Lydecker JA, Grilo CM, Barnes RD. Getting a head start: identifying pretreatment correlates associated with early weight loss for individuals participating in weight loss treatment. Translational Behavioral Medicine 2019, 11: 236-243. PMID: 31816053, PMCID: PMC7877303, DOI: 10.1093/tbm/ibz149.Peer-Reviewed Original ResearchConceptsEarly weight lossWeight loss treatmentUsual careWeight lossLow pretreatmentDepressive symptomsWeek sixMeaningful weight lossPrimary care settingBinge-eating disorder diagnosisEating Disorder Examination interviewGreater weight lossNutrition psychoeducationTreatment cessationPercent weight lossPrimary careNPC groupObesity rangeLoss treatmentEmotional overeatingExamination interviewDisorder diagnosisPretreatment correlatesMotivational interviewingTreatmentPatients' reasons for weight loss and their relations to clinical weight loss outcomes in a comprehensive lifestyle intervention
Boepple L, Cero I, Marek RJ, Coulon S, Lydecker JA, Brown JD, Malcolm R, O'Neil PM. Patients' reasons for weight loss and their relations to clinical weight loss outcomes in a comprehensive lifestyle intervention. Obesity Science & Practice 2019, 5: 548-554. PMID: 31890245, PMCID: PMC6934423, DOI: 10.1002/osp4.372.Peer-Reviewed Original ResearchWeight loss outcomesBody mass indexWeight change outcomesLoss outcomesWeight lossWhite patientsBlack patientsHigher Body Mass IndexComprehensive lifestyle interventionWeight loss trajectoriesCertain patient groupsWeight loss treatmentWeight loss programLifestyle interventionPatient characteristicsMale patientsPatients' reasonsFemale patientsMass indexPercent weight lossLoss programPatient groupWorse outcomesDoctor's recommendationLoss treatment
2018
Pain and modifiable risk factors among weight loss seeking Veterans with overweight
Godfrey KM, Bullock AJ, Dorflinger LM, Min KM, Ruser CB, Masheb RM. Pain and modifiable risk factors among weight loss seeking Veterans with overweight. Appetite 2018, 128: 100-105. PMID: 29885382, DOI: 10.1016/j.appet.2018.06.010.Peer-Reviewed Original ResearchConceptsBody mass indexWeight loss treatmentMental health symptomsModifiable risk factorsHigher pain intensityPain intensityLoss treatmentHealth symptomsRisk factorsAverage body mass indexBehavioral weight loss treatmentSelf-reported pain ratingsOverweight/obesitySample of veteransElectronic medical recordsVA ConnecticutClinical characteristicsSevere painChronic painMass indexOutpatient clinicPain ratingsMedical recordsNight eatingSelf-report questionnairesEarly weight loss predicts weight loss treatment response regardless of binge‐eating disorder status and pretreatment weight change
Barnes RD, Ivezaj V, Pittman BP, Grilo CM. Early weight loss predicts weight loss treatment response regardless of binge‐eating disorder status and pretreatment weight change. International Journal Of Eating Disorders 2018, 51: 558-564. PMID: 29637592, PMCID: PMC6002900, DOI: 10.1002/eat.22860.Peer-Reviewed Original ResearchConceptsEarly weight lossWeight loss treatmentBinge-eating disorderLoss treatmentWeight lossBed statusWeight loss treatment outcomesOverweight/obesityWeight loss trialAverage weight lossWeight-related variablesPrognostic significancePrimary careTreatment outcomesTreatment responseLoss trialWeight trajectoriesTreatment studiesDisorder statusWeight changeOutcomesTreatmentIndividual responsesStatusPositive outcomes
2016
Gender-related Differences in Food Craving and Obesity.
Hallam J, Boswell RG, DeVito EE, Kober H. Gender-related Differences in Food Craving and Obesity. The Yale Journal Of Biology And Medicine 2016, 89: 161-73. PMID: 27354843, PMCID: PMC4918881.Peer-Reviewed Original ResearchConceptsGender-related differencesFood cravingsWeight loss treatmentWeight-related outcomesMore effective treatmentsGender differencesMenstrual cycleEffective treatmentLoss treatmentObesity epidemicObesityTreatment approachesClear gender differencesHealth consequencesWeight lossGender-based differencesCravingTreatmentAddiction literatureDifferencesPrevalenceFood Thought Suppression Inventory: Test–retest reliability and relationship to weight loss treatment outcomes
Barnes RD, Ivezaj V, Grilo CM. Food Thought Suppression Inventory: Test–retest reliability and relationship to weight loss treatment outcomes. Eating Behaviors 2016, 22: 93-95. PMID: 27112114, PMCID: PMC5161461, DOI: 10.1016/j.eatbeh.2016.04.001.Peer-Reviewed Original ResearchConceptsFood Thought Suppression InventoryWeight loss treatmentBinge-eating episodesTest-retest reliabilityLoss treatmentWeight loss treatment outcomesWeight lossWeight loss goalsOriginal body weightWeek test-retest reliabilityPercent weight lossPrimary careTreatment outcomesIntra-class correlationBody weightBaselineTreatmentScoresEpisodesParticipantsPost assessmentHigh levelsBinge
2014
High‐frequency binge eating predicts weight gain among veterans receiving behavioral weight loss treatments
Masheb RM, Lutes LD, Kim HM, Holleman RG, Goodrich DE, Janney CA, Kirsh S, Richardson CR, Damschroder LJ. High‐frequency binge eating predicts weight gain among veterans receiving behavioral weight loss treatments. Obesity 2014, 23: 54-61. PMID: 25385705, DOI: 10.1002/oby.20931.Peer-Reviewed Original ResearchConceptsWeight loss treatmentWaist circumferenceLoss treatmentBody weightObese samplePoorer weight loss outcomesBehavioral weight loss treatmentBehavioral weight loss programWeight gainWeight lossWeight loss outcomesOverweight/obesityWeight loss programPresence of bingeFrequency of bingeASPIRE studyLoss programWorse outcomesBinge groupEffectiveness trialLoss outcomesSecondary analysisBinge eatingBingeVeteransA randomized controlled trial comparing scalable weight loss treatments in primary care
Barnes RD, White MA, Martino S, Grilo CM. A randomized controlled trial comparing scalable weight loss treatments in primary care. Obesity 2014, 22: 2508-2516. PMID: 25298016, PMCID: PMC4236282, DOI: 10.1002/oby.20889.Peer-Reviewed Original ResearchConceptsNutrition psychoeducationUsual careAttention control interventionMotivational interviewingTreatment adherenceWeight lossOverweight/obese patientsBed statusWeight loss outcomesPrimary care settingWeight loss treatmentWeight loss resultsObese patientsTriglyceride levelsPrimary careObesity interventionsNPC patientsLoss outcomesLoss treatmentDepression scoresScalable interventionsPatientsTreatment disseminationSuperior benefitsInterventionComparing weight gain in the year prior to treatment for overweight and obese patients with and without binge eating disorder in primary care
Ivezaj V, Kalebjian R, Grilo CM, Barnes RD. Comparing weight gain in the year prior to treatment for overweight and obese patients with and without binge eating disorder in primary care. Journal Of Psychosomatic Research 2014, 77: 151-154. PMID: 25077857, PMCID: PMC4118055, DOI: 10.1016/j.jpsychores.2014.05.006.Peer-Reviewed Original ResearchConceptsObese patientsBED patientsBinge-eating frequencyWeight gainPrimary careWeight changeCurrent weightGreater eating-disorder psychopathologyNBO patientsWeight change trajectoriesPrimary care physiciansWeight loss treatmentBeck Depression Inventory-IIFurther weight gainEating-disorder psychopathologyRapid weight gainEating Disorder ExaminationCare physiciansWeight historySelf-report questionnairesOverall groupDepression scoresIndependent significant contributionPatientsOverweight
2012
Prognostication for body contouring surgery after bariatric surgery.
Singh D, Forte AJ, Zahiri HR, Janes LE, Sabino J, Matthews JA, Bell RL, Thomson JG. Prognostication for body contouring surgery after bariatric surgery. Eplasty 2012, 12: e46. PMID: 22993644, PMCID: PMC3443410.Peer-Reviewed Original ResearchPercent excess weight lossExcess weight lossBody mass indexMean percent excess weight lossBariatric surgery patientsMass indexGroup IIGroup IWeight lossBariatric surgerySurgery patientsMean agePreoperative body mass indexExcess body weightGastric bypass surgeryPopulation of patientsUseful predictive factorWeight loss treatmentBypass surgeryPredictive factorsLoss treatmentPatientsSurgeryBody weightElicit factors
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