2024
Artificial intelligence in ophthalmology
Khossravi A, Chen Q, Adelman R. Artificial intelligence in ophthalmology. Current Opinion In Ophthalmology 2024, 36: 35-38. PMID: 39607311, DOI: 10.1097/icu.0000000000001111.Peer-Reviewed Original ResearchConceptsTreatment of diabetic retinopathyImprove accuracy of diagnosisProgression of diseasePersonalized treatment plansCorneal infectionVisual outcomeIntraocular pressureMacular degenerationDiabetic retinopathyAccuracy of diagnosisFollow-upTreatment planningOcular imagingPersonalization of medicinePredictive of progression of diseasePatient outcomesDiagnosisEnhance patient outcomesIncorporation of genomicsTreatmentHome monitoringOutcomesCornealGlaucomaEctasiaEndophthalmitis in Eyes Treated with the Port Delivery System with Ranibizumab Summary of Cases during Clinical Trial Development
Eichenbaum D, Freeman W, Chang M, Brooks L, Chaudhry N, Dadgostar H, McCannel C, Michels M, Mittra R, Wolfe J, Beindl V, Jaycock P, Bobbala A, Gune S, Spicer G, Callaway N. Endophthalmitis in Eyes Treated with the Port Delivery System with Ranibizumab Summary of Cases during Clinical Trial Development. Ophthalmology Retina 2024, 9: 127-143. PMID: 39154860, DOI: 10.1016/j.oret.2024.08.005.Peer-Reviewed Original ResearchPort Delivery SystemEndophthalmitis casesConjunctival complicationsFollow-upNeovascular age-related macular degenerationBox warningTreated with intravitreal antibioticsAge-related macular degenerationMonthly intravitreal ranibizumabRisk of endophthalmitisPDS implantUS Prescribing InformationImmediate postoperative periodClinical trial developmentETDRS lettersIntravitreal antibioticsIntravitreal ranibizumabDelivery systemSafety populationVisual outcomeMacular degenerationOcular proceduresRetrospective reviewVision lossEndophthalmitis
2021
Outcomes of 25-gauge pars plana vitrectomy for cytomegalovirus retinitis-related retinal detachment
Moharana B, Dogra M, Tigari B, Singh S, Katoch D, Arora A, Singh R. Outcomes of 25-gauge pars plana vitrectomy for cytomegalovirus retinitis-related retinal detachment. Indian Journal Of Ophthalmology 2021, 69: 2361-2366. PMID: 34427223, PMCID: PMC8544073, DOI: 10.4103/ijo.ijo_3539_20.Peer-Reviewed Original ResearchConceptsBest-corrected visual acuityPars plana vitrectomyLogMAR best-corrected visual acuityComplete anatomic successAnatomical successPlana vitrectomyRetinal detachmentPostoperative logMAR best-corrected visual acuityPreoperative logMAR best-corrected visual acuityFollow-upRetinitis-related retinal detachmentRetrospective consecutive case seriesAttachment of retinaMicroincision vitrectomy surgeryRetinal reattachment rateRhegmatogenous retinal detachmentConsecutive case seriesHuman immunodeficiency virusInferior detachmentVisual outcomeVitrectomy surgeryReattachment rateVisual acuityImmunodeficiency virusHematologic malignanciesHEMORRHAGIC OCCLUSIVE RETINAL VASCULITIS AFTER INTRACAMERAL VANCOMYCIN USE IN CATARACT SURGERY AFTER INTRAVENOUS EXPOSURE
Alasil T, Wong JJY, Adelman RA, Tom D, Coady PA. HEMORRHAGIC OCCLUSIVE RETINAL VASCULITIS AFTER INTRACAMERAL VANCOMYCIN USE IN CATARACT SURGERY AFTER INTRAVENOUS EXPOSURE. Retinal Cases & Brief Reports 2021, Publish Ahead of Print: &na;. PMID: 29474222, DOI: 10.1097/icb.0000000000000725.Peer-Reviewed Original ResearchConceptsHemorrhagic occlusive retinal vasculitisOcclusive retinal vasculitisCataract surgeryLeft eyeIntracameral vancomycinRetinal vasculitisSystemic vancomycinHypersensitivity reactionsPan-retinal photocoagulationPeripheral retinal hemorrhagesFavorable visual outcomeUncomplicated cataract surgeryOral prednisoneFundus examinationRetinal ischemiaVisual outcomeFellow eyesInfection prophylaxisRetinal hemorrhagesBlurry visionVisual acuityAnterior chamberIntraocular lensIschemic areaVasculitis cases
2020
Nontubercular Mycobacteria Associated Uveitis in HIV Positive Patients
Sharma K, Menia N, Bajgai P, Sharma M, Sharma A, Katoch D, Singh R. Nontubercular Mycobacteria Associated Uveitis in HIV Positive Patients. Ocular Immunology And Inflammation 2020, 30: 21-28. PMID: 32813606, DOI: 10.1080/09273948.2020.1788610.Peer-Reviewed Original ResearchConceptsHIV-positive patientsPositive patientsNontuberculous mycobacteriaStudy of HIV-positive patientsPoor visual outcomeAnti-tuberculosis therapyNontuberculous mycobacterium infectionAssociated uveitisNecrotizing retinitisVisual outcomeVisual acuityRetrospective studyClinical featuresUveitisAnti-tuberculosisPatientsHIVEyesOutcomesPCREndophthalmitisChorioretinitisAcuityRetinitisTherapyClinical Etiologies, Microbial Spectrum, Antibiotic Susceptibilities, and Visual Acuity Outcomes of Acute Endophthalmitis
Lu LJ, Chen X, Adelman RA. Clinical Etiologies, Microbial Spectrum, Antibiotic Susceptibilities, and Visual Acuity Outcomes of Acute Endophthalmitis. Journal Of Ocular Pharmacology And Therapeutics 2020, 36: 534-539. PMID: 32609038, DOI: 10.1089/jop.2018.0074.Peer-Reviewed Original ResearchConceptsVisual acuity outcomesClinical etiologyAntibiotic susceptibilityMicrobial spectrumAcute endophthalmitisAcuity outcomesPostoperative infectionCorneal ulcersCataract extractionEtiology of endophthalmitisFinal VA outcomesTertiary referral centerMajority of patientsRetrospective chart reviewICD-10 codesSpectrum of pathogensCommon inciting factorCulture-proven endophthalmitisChart reviewReferral centerVisual outcomeVA outcomesExogenous endophthalmitisClinical recordsMedical recordsVISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two.
Soliman MK, Gini G, Kuhn F, Parolini B, Ozdek S, Adelman RA, Sallam AB. VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two. Retina 2020, 41: 423-430. PMID: 32467482, DOI: 10.1097/iae.0000000000002856.Peer-Reviewed Original ResearchConceptsIntravitreal antibioticsPPV groupEarly PPVVisual outcomeRetinal detachmentPostintravitreal injection endophthalmitisRetrospective multicenter cohortFinal visual acuityWeeks of presentationDays of presentationMethod of treatmentEarly vitrectomyMulticenter cohortIntravitreal injectionPlana vitrectomyRetina specialistsVisual acuityMean ageIntraocular proceduresEndophthalmitisSimilar outcomesLight perceptionEyesVitrectomyOutcomesPosterior hypopyon in fungal endogenous endophthalmitis secondary to presumably contaminated dextrose infusion
Karkhur S, Afridi R, Menia N, Gupta N, Nguyen Q, Dogra M, Katoch D. Posterior hypopyon in fungal endogenous endophthalmitis secondary to presumably contaminated dextrose infusion. American Journal Of Ophthalmology Case Reports 2020, 18: 100681. PMID: 32373756, PMCID: PMC7191180, DOI: 10.1016/j.ajoc.2020.100681.Peer-Reviewed Original ResearchPars plana vitrectomyEndogenous endophthalmitisCounting fingersLeft eyeDextrose infusionBest-corrected visual acuityDiagnosis of endogenous endophthalmitisDiagnostic pars plana vitrectomySystemic anti-fungal treatmentTime of initial presentationEvidence of fungal elementsFungal endogenous endophthalmitisIntravenous dextrose infusionSlit-lamp examinationEpisodes of feverAnti-fungal treatmentAsian Indian femaleDense vitritisPlana vitrectomyTopical cycloplegicsVisual outcomeDecreased visionFundus photographyAnterior chamberVisual acuity
2018
Streptococcus Dysgalactiae Subspecies Equisimilis Endogenous Endophthalmitis Associated with Aortic Valve Abscess
Gupta A, Tsui E, Sarrafpour S, Lee CM, Modi YS. Streptococcus Dysgalactiae Subspecies Equisimilis Endogenous Endophthalmitis Associated with Aortic Valve Abscess. Ocular Immunology And Inflammation 2018, 27: 743-746. PMID: 29969334, DOI: 10.1080/09273948.2018.1489062.Peer-Reviewed Original ResearchConceptsLeft eyeAortic valveVisual acuityAnterior chamber fibrinSevere intraocular infectionPoor visual outcomeRetrospective case reportEndogenous endophthalmitisIntraocular infectionVisual outcomeEndophthalmitis AssociatedVitreous inflammationIntravitreal injectionScan ultrasonographyVitreous tapRight eyeCase reportBlood culturesHyperechoic areasWhite malesAcuityEyesVancomycinStreptococciInjection
2017
Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas?
Omay SB, Almeida JP, Chen YN, Shetty SR, Liang B, Ni S, Anand VK, Schwartz TH. Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas? Journal Of Neurosurgery 2017, 129: 642-647. PMID: 29171802, DOI: 10.3171/2017.6.jns163188.Peer-Reviewed Original ResearchConceptsGross total resectionExtended endonasal approachSubtotal resectionLarge tumorsPituitary glandFirst-line surgical approachEndonasal endoscopic resectionAvailable preoperative imagingMidline craniopharyngiomasOBJECTIVE CraniopharyngiomasPrefixed chiasmEndocrine outcomesRelative contraindicationVisual outcomeEndoscopic resectionAuthors' centerPreoperative imagingOptic chiasmSurgical approachVisual deteriorationResults ThirtyPituitary stalkThird ventricleHigh riskResectionAge‐related macular degeneration: using morphological predictors to modify current treatment protocols
Ashraf M, Souka A, Adelman RA. Age‐related macular degeneration: using morphological predictors to modify current treatment protocols. Acta Ophthalmologica 2017, 96: 120-133. PMID: 29130626, DOI: 10.1111/aos.13565.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationPigment epithelial detachmentChoroidal neovascular membranePosterior vitreous detachmentNeovascular age-related macular degenerationRetinal angiomatous proliferationSubretinal fluidIntraretinal cystsVitreomacular adhesionVisual outcomeVisual acuityPrognostic indicatorMacular degenerationAnti-vascular endothelial growth factorLarger choroidal neovascular membranesWet age-related macular degenerationOlder ageCNV sizeFinal visual outcomeGood visual outcomeAnti-VEGF therapyPoor prognostic indicatorCurrent treatment protocolsEndothelial growth factorInjection frequencyLimitations of the endonasal endoscopic approach in treating olfactory groove meningiomas. A systematic review
Shetty SR, Ruiz-Treviño AS, Omay SB, Almeida JP, Liang B, Chen YN, Singh H, Schwartz TH. Limitations of the endonasal endoscopic approach in treating olfactory groove meningiomas. A systematic review. Acta Neurochirurgica 2017, 159: 1875-1885. PMID: 28831590, DOI: 10.1007/s00701-017-3303-0.Peer-Reviewed Original ResearchConceptsExtent of resectionOlfactory groove meningiomasTCA groupEndoscopic endonasalEEA patientsEEA groupTraditional transcranialPreoperative visual disturbancesMedium-sized tumorsFischer's exact testEndonasal endoscopic approachT-testStudent's t-testCurrent management strategiesPostoperative anosmiaPreoperative anosmiaTCA patientsPostoperative complicationsVisual outcomeEndoscopic resectionVisual disturbancesRecurrence rateSkull base reconstructionEndoscopic approachCSF leakCharacteristics and racial variations of polypoidal choroidal vasculopathy in tertiary centers in the United States and United Kingdom
Alasil T, Munoz N, Keane PA, Tufail A, Coady PA, Novais E, de Carlo TE, Baumal CR, Waheed NK, Duker JS, Adelman RA. Characteristics and racial variations of polypoidal choroidal vasculopathy in tertiary centers in the United States and United Kingdom. International Journal Of Retina And Vitreous 2017, 3: 9. PMID: 28428893, PMCID: PMC5392942, DOI: 10.1186/s40942-017-0060-4.Peer-Reviewed Original ResearchPolypoidal choroidal vasculopathyFinal visual acuityWorse visual outcomeVisual acuityBilateral diseaseVisual outcomeTertiary centerFemale predominanceChoroidal vasculopathyDiagnosis of PCVInitial visual acuityRacial variationMulticenter retrospective studyLength of followDifferent treatment modalitiesSignificant decreaseIndocyanine green angiography imagesLens statusPCV patientsVision gainInitial presentationRetrospective studyWorse visionPolypoidal lesionsTreatment modalitiesComparison and analysis of FDA reported visual outcomes of the three latest platforms for LASIK: wavefront guided Visx iDesign, topography guided WaveLight Allegro Contoura, and topography guided Nidek EC-5000 CATz
Moshirfar M, Shah T, Skanchy D, Linn S, Kang P, Durrie D. Comparison and analysis of FDA reported visual outcomes of the three latest platforms for LASIK: wavefront guided Visx iDesign, topography guided WaveLight Allegro Contoura, and topography guided Nidek EC-5000 CATz. Clinical Ophthalmology 2017, 11: 135-147. PMID: 28115827, PMCID: PMC5221655, DOI: 10.2147/opth.s115270.Peer-Reviewed Original ResearchUncorrected distance visual acuityDistance visual acuityVisual outcomeVisual acuityNidek ECPostoperative uncorrected distance visual acuityMean postoperative uncorrected distance visual acuityContrast sensitivityRetrospective comparative studyMesopic contrast sensitivitySummary of SafetyPhotopic contrast sensitivitySignificant increaseDrug administration dataFDA dataLASIK surgeryOutcome measurementsUS FoodContouraMonthsAdministration dataStatistical significanceAnalysis of FDAIDesignOutcomes
2016
Programs for Detecting and Treating Retinopathy of Prematurity: Role of the Neonatal Team.
Grover S, Katoch D, Dogra M, Kumar P. Programs for Detecting and Treating Retinopathy of Prematurity: Role of the Neonatal Team. Indian Pediatrics 2016, 53 Suppl 2: s93-s99. PMID: 27915314.Peer-Reviewed Original ResearchConceptsRetinopathy of prematurityFollow-up of high-risk infantsNational Program for Control of BlindnessTreatment of retinopathy of prematurityEvidence-based screening policySevere retinopathy of prematurityTreat retinopathy of prematurityNeonatal care teamNeonatal care unitHigh-risk infantsHome-based neonatal careRashtriya Bal Swasthya KaryakramControl of blindnessClinical practice guidelinesTreated retinopathyPreterm infantsVisual outcomeSevere retinopathyNeonatal careNeonatal teamFollow-upCare unitScreening policyPost-operative supportEarly identificationPredicting outcomes to anti-vascular endothelial growth factor (VEGF) therapy in diabetic macular oedema: a review of the literature
Ashraf M, Souka A, Adelman R. Predicting outcomes to anti-vascular endothelial growth factor (VEGF) therapy in diabetic macular oedema: a review of the literature. British Journal Of Ophthalmology 2016, 100: 1596. PMID: 27231313, DOI: 10.1136/bjophthalmol-2016-308388.Peer-Reviewed Original ResearchConceptsDiabetic macular edemaOptical coherence tomographyMacular edemaAnti-vascular endothelial growth factor therapyIntravitreal anti-vascular endothelial growth factorAnti-vascular endothelial growth factorEndothelial growth factor therapyFluorescein angiography findingsAnti-VEGF therapyAnti-VEGF agentsGrowth factor therapyCourse of treatmentCommon prognostic indicatorsEndothelial growth factorFactor therapyMost patientsVisual outcomeAngiography findingsChoroidal thicknessLarge RCTsTreatment regimenOCT parametersVisual acuityPrognostic indicatorDifferent RCTsRisk factors for visual impairment associated with corneal diseases in southern China
Xu SC, Chow J, Liu J, Li L, Maslin JS, Chadha N, Chen B, Teng CC. Risk factors for visual impairment associated with corneal diseases in southern China. Clinical Ophthalmology 2016, 10: 777-782. PMID: 27194904, PMCID: PMC4859424, DOI: 10.2147/opth.s103302.Peer-Reviewed Original ResearchInfectious keratitisCorneal diseaseRisk factorsVisual impairmentRural residenceTraditional Chinese medicineVisual outcomeConsecutive patientsMale sexOdds ratioOlder ageChinese medicineWorld Health Organization recommendationsWorse visual outcomeDry eye syndromeSignificant risk factorsSecond Xiangya HospitalCross-sectional studyLogistic regression modelsCentral South UniversityBinary logistic regression modelCorneal abrasionCornea clinicNoninfectious etiologiesOcular trauma
2015
Intravenous Fibrinolytic Therapy in Central Retinal Artery Occlusion: A Patient-Level Meta-analysis
Schrag M, Youn T, Schindler J, Kirshner H, Greer D. Intravenous Fibrinolytic Therapy in Central Retinal Artery Occlusion: A Patient-Level Meta-analysis. JAMA Neurology 2015, 72: 1148-1154. PMID: 26258861, DOI: 10.1001/jamaneurol.2015.1578.Peer-Reviewed Original ResearchConceptsCentral retinal artery occlusionRetinal artery occlusionSystemic fibrinolytic therapyVisual acuity outcomesPatient-level dataNatural history groupConservative treatmentFibrinolytic therapyArtery occlusionAcuity outcomesPatient-Level Meta-AnalysisIntravenous fibrinolytic therapyAnterior chamber paracentesisAbsolute risk reductionOutcome of treatmentNatural history studiesTissue plasminogen activatorRandom-effects modelRelevant review articlesWeb of ScienceFibrinolysis treatmentConservative therapyRetinal ischemiaVisual outcomeConservative modalitiesVisual recovery following open globe injury with initial no light perception
Han YS, Kavoussi SC, Adelman RA. Visual recovery following open globe injury with initial no light perception. Clinical Ophthalmology 2015, 9: 1443-1448. PMID: 26316683, PMCID: PMC4540122, DOI: 10.2147/opth.s87852.Peer-Reviewed Original ResearchOpen globe injuriesVisual recoveryGlobe injuriesExact testLight perceptionOcular Trauma ScoreOcular examination findingsCharacteristics of injuriesFisher's exact testUnpaired t-testSecondary enucleationVisual outcomeConsecutive patientsExamination findingsSurgical interventionVisual acuityMean agePrognostic indicatorSingle institutionOphthalmic historyTrauma ScoreInclusion criteriaPatientsSelect casesWound size
2014
Aflibercept in the Treatment of Neovascular Age-Related Macular Degeneration in Previously Treated Patients
Hall LB, Zebardast N, Huang JJ, Adelman RA. Aflibercept in the Treatment of Neovascular Age-Related Macular Degeneration in Previously Treated Patients. Journal Of Ocular Pharmacology And Therapeutics 2014, 30: 346-352. PMID: 24552305, DOI: 10.1089/jop.2013.0188.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAntibodies, Monoclonal, HumanizedBevacizumabFemaleHumansIntravitreal InjectionsMacular DegenerationMaleRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinaRetrospective StudiesTomography, Optical CoherenceTreatment OutcomeVascular Endothelial Growth Factor AVisual AcuityConceptsAge-related macular degenerationCentral macular thicknessAflibercept injectionsInitial visitMacular degenerationAnti-vascular endothelial growth factor treatmentNeovascular age-related macular degenerationEndothelial growth factor treatmentCentral macular edemaIntraocular pressure increaseSubset of patientsMain outcome measuresOptical coherence tomographyGrowth factor treatmentMacular thicknessNeovascular AgeOcular hypertensionSubmacular fluidVisual outcomeMacular edemaRetrospective studyVisual acuityOutcome measuresStudy populationPatients
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