2024
Correlation between changes in apathy and cognition in Alzheimer’s disease associated apathy: Analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2)
Sankhe K, Tumati S, Perin J, Rivet L, Vieira D, Rosenberg P, Herrmann N, Shade D, Lerner A, Padala P, Brawman-Mintzer O, van Dyck C, Porsteinsson A, Craft S, Levey A, Mintzer J, Lanctôt K. Correlation between changes in apathy and cognition in Alzheimer’s disease associated apathy: Analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2). International Psychogeriatrics 2024, 37: 100012. PMID: 40086910, DOI: 10.1016/j.inpsyc.2024.100012.Peer-Reviewed Original ResearchBoston Naming TestMini-Mental State ExamCategory fluencyMild-to-moderate AD patientsClinically significant apathyCognitive change scoresModerate AD patientsHopkins Verbal LearningVerbal learningDigit spanNaming TestVerbal fluencySignificant apathyTrail MakingCognitive changesMeasure apathyMethylphenidateCognitionCognitive scoresState ExamMini-MentalChange scoresApathyAD patientsTrial 2Correlation between changes in apathy and cognition in Alzheimer’s disease associated apathy: analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2)
Sankhe K, Tumati S, Perin J, Rivet L, Vieira D, Rosenberg P, Herrmann N, Shade D, Lerner A, Padala P, Brawman‐Mintzer O, van Dyck C, Porsteinsson A, Craft S, Levey A, Mintzer J, Lanctôt K. Correlation between changes in apathy and cognition in Alzheimer’s disease associated apathy: analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2). Alzheimer's & Dementia 2024, 20: e091793. PMCID: PMC11710533, DOI: 10.1002/alz.091793.Peer-Reviewed Original ResearchMini-Mental State ExamBoston Naming TestDigit Span ForwardCategory fluencyWorsening apathyNPI-aCognitive testsAlzheimer's diseaseCognitive change scoresAssociated with cognitive impairmentBaseline cognitive test scoresCognitive test scoresMild to moderate ADAssociated with performanceNaming TestVerbal fluencyExecutive functionMethylphenidate treatmentMethylphenidate groupTrail MakingCognitive domainsCognitive changesMethylphenidatePlacebo-controlled trialNPI-apathyNormative data for verbal fluency and naming tests in Spanish-speaking adults in the United States
Olabarrieta-Landa L, Rivera D, Xia B, Moreno O, Usuga D, Valdés G, Lopez E, Rodriguez M, Carrión C, Lequerica A, Drago C, García P, Rivera P, Perrin P, Arango-Lasprilla J. Normative data for verbal fluency and naming tests in Spanish-speaking adults in the United States. NeuroRehabilitation An International Interdisciplinary Journal 2024, 55: 195-208. PMID: 39213096, DOI: 10.3233/nre-240087.Peer-Reviewed Original ResearchConceptsBoston Naming TestVerbal fluency testSemantic verbal fluency testSpanish-Speaking AdultsFluency testNaming TestSpanish proficiencyNormative dataSpanish-speaking populationLinguistic deficitsVerbal fluencyNeuropsychological NormsTest performanceSpanish speakersTest scoresU.S. participantsPhonemeProficiencyEducational interactionCultural variablesSignificant interactionAdultsImprove accuracy of diagnosisNeurodegenerative disordersAcculturation
2022
Cognition in older adults with bipolar disorder: An ISBD task force systematic review and meta‐analysis based on a comprehensive neuropsychological assessment
Montejo L, Torrent C, Jiménez E, Martínez‐Arán A, Blumberg HP, Burdick KE, Chen P, Dols A, Eyler LT, Forester BP, Gatchel JR, Gildengers A, Kessing LV, Miskowiak KW, Olagunju AT, Patrick RE, Schouws S, Radua J, del M. Bonnín C, Vieta E, Force I. Cognition in older adults with bipolar disorder: An ISBD task force systematic review and meta‐analysis based on a comprehensive neuropsychological assessment. Bipolar Disorders 2022, 24: 115-136. PMID: 34978124, DOI: 10.1111/bdi.13175.Peer-Reviewed Original ResearchConceptsComprehensive neuropsychological assessmentNeuropsychological assessmentCognitive domainsExecutive functionProcessing speedAttention/processing speedOlder adultsDetailed neuropsychological profileEuthymic older adultsComplete neuropsychological assessmentEffect sizeModerate effect sizeCognitive flexibilityVerbal learningMemory domainImmediate memoryVerbal fluencyCognitive performanceNeuropsychological profileOABD patientsSignificant effect sizeBipolar disorderCognitive functionOABDLarge significant effect sizes
2018
Presurgical language fMRI: Technical practices in epilepsy surgical planning
Benjamin CFA, Dhingra I, Li AX, Blumenfeld H, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen RA, Warfield SK, Peters JM, Reutens D, Połczyńska MM, Hirsch LJ, Spencer DD. Presurgical language fMRI: Technical practices in epilepsy surgical planning. Human Brain Mapping 2018, 39: 4032-4042. PMID: 29962111, PMCID: PMC6175127, DOI: 10.1002/hbm.24229.Peer-Reviewed Original ResearchConceptsLanguage functional MRIFunctional MRISurgical planningEpilepsy surgical planningEpilepsy surgical programsGeneral linear modelingBlood flowClinical practicePatient careSurgical programsRoutine useMarked heterogeneityClinical applicationVerbal fluencyData highlightFMRI dataMost programsPatientsWidespread useEpilepsyIndividualsMRICare
2017
A review of the effects of very low nicotine content cigarettes on behavioral and cognitive performance
Keith D, Kurti A, Davis D, Zvorsky I, Higgins S. A review of the effects of very low nicotine content cigarettes on behavioral and cognitive performance. Preventive Medicine 2017, 104: 100-116. PMID: 28647546, PMCID: PMC5831363, DOI: 10.1016/j.ypmed.2017.06.016.Peer-Reviewed Original ResearchMinimal effects of prolonged smoking abstinence or resumption on cognitive performance challenge the “self-medication” hypothesis in schizophrenia
Boggs DL, Surti TS, Esterlis I, Pittman B, Cosgrove K, Sewell RA, Ranganathan M, D'Souza DC. Minimal effects of prolonged smoking abstinence or resumption on cognitive performance challenge the “self-medication” hypothesis in schizophrenia. Schizophrenia Research 2017, 194: 62-69. PMID: 28392208, PMCID: PMC5630481, DOI: 10.1016/j.schres.2017.03.047.Peer-Reviewed Original ResearchConceptsProcessing speedMultiple cognitive domainsCognitive test performancePro-cognitive effectsSelf-medication hypothesisNicotine-dependent smokersVerbal memoryVerbal recallCognitive batteryCognitive domainsExecutive functionVerbal fluencyBehavioral measuresTest batteryCognitive deficitsTest performanceSmoking cessationSmoking abstinenceNegative symptomsConflict resolutionAbstinenceCognitionDepressive symptomsSchizophreniaSmoke cigarettes92. Peripheral Oxytocin and Vasopressin Modulates Regional Brain Activity Differently in Men and Women With Schizophrenia
Rubin L, Li S, Yao L, Keedy S, Reilly J, Hill S, Bishop J, Carter S, Pournajafi-Nazarloo H, Drogos L, Gershon E, Pearlson G, Tamminga C, Clementz B, Keshavan M, Lui S, Sweeney J. 92. Peripheral Oxytocin and Vasopressin Modulates Regional Brain Activity Differently in Men and Women With Schizophrenia. Schizophrenia Bulletin 2017, 43: s50-s50. PMCID: PMC5475587, DOI: 10.1093/schbul/sbx021.131.Peer-Reviewed Original ResearchHigher AVP levelsHigher ALFFMale patientsCerebellar cortexFrontal cortexArginine vasopressinHigher OT levelsPosterior cingulateOT levelsFemale patientsLower ALFFAVP levelsPoor verbal fluencyHealthy individualsRegional cerebral functionSpontaneous neuronal activitySex-dependent mannerAVP serum concentrationsBrain activityRegional brain activityVerbal fluencyEmotion processingSuperior temporal gyrusClinical associationsSerum concentrations
2014
Behavioral and Neural Correlates of Executive Functioning in Musicians and Non-Musicians
Zuk J, Benjamin C, Kenyon A, Gaab N. Behavioral and Neural Correlates of Executive Functioning in Musicians and Non-Musicians. PLOS ONE 2014, 9: e99868. PMID: 24937544, PMCID: PMC4061064, DOI: 10.1371/journal.pone.0099868.Peer-Reviewed Original ResearchConceptsExecutive functionMusical trainingUntrained childrenEF skillsNeural correlatesVerbal fluencyConstruct of EFSMA/SMACognitive flexibilityEF batteryExecutive functioningAdult musiciansCognitive skillsCognitive capacityBrain activationRight VLPFCGreater activationProcessing speedAcademic achievementAcademic abilityRule representationEF regionFluencyMethodological limitationsMusicians
2011
Are Time- and Event-based Prospective Memory Comparably Affected in HIV Infection?†
Zogg J, Woods S, Weber E, Doyle K, Grant I, Group T, Atkinson J, Ellis R, McCutchan J, Marcotte T, Hale B, Ellis R, McCutchan J, Letendre S, Capparelli E, Schrier R, Heaton R, Cherner M, Moore D, Jernigan T, Fennema-Notestine C, Archibald S, Hesselink J, Annese J, Taylor M, Masliah E, Everall I, Langford T, Richman D, Smith D, McCutchan J, Everall I, Lipton S, McCutchan J, Atkinson J, Ellis R, Letendre S, Atkinson J, von Jaeger R, Gamst A, Cushman C, Masys D, Abramson I, Ake C, Vaida F. Are Time- and Event-based Prospective Memory Comparably Affected in HIV Infection?†. Archives Of Clinical Neuropsychology 2011, 26: 250-259. PMID: 21459901, PMCID: PMC3081684, DOI: 10.1093/arclin/acr020.Peer-Reviewed Original ResearchConceptsEvent-based ProMIntentions Screening TestTime-based tasksEvent-based tasksMulti-process theoryTrend-level effectsProspective memoryCue typesCognitive architectureAttention/Executive functionVerbal fluencyPrefrontal systemsSubset of participantsStrategic monitoringParallel subscalesGreater deficitsRetrieval processStrategic processMemoryMain effectNeurocognitive disordersTaskDeficitsPrior studies
2010
The semantic organization of the animal category: evidence from semantic verbal fluency and network theory
Goñi J, Arrondo G, Sepulcre J, Martincorena I, Vélez de Mendizábal N, Corominas-Murtra B, Bejarano B, Ardanza-Trevijano S, Peraita H, Wall D, Villoslada P. The semantic organization of the animal category: evidence from semantic verbal fluency and network theory. Cognitive Processing 2010, 12: 183-196. PMID: 20938799, DOI: 10.1007/s10339-010-0372-x.Peer-Reviewed Original ResearchConceptsSemantic verbal fluencyVerbal fluency testSemantic memoryVerbal fluencyFluency testFluency experienceSemantic organizationHuman memoryNatural categoriesAnimal categoriesStored knowledgeRetrieval mechanismRecovery criteriaCo-occurrence approachKnowledge of conceptsConceptual structureMemorySemantic informationNetwork modelCo-occurring conceptsNetwork outcomesHuman ratersFluencyExpert human ratersHuman evaluationPredictors of Participation in Community Outpatient Psychosocial Rehabilitation in Schizophrenia
Kurtz MM, Rose J, Wexler BE. Predictors of Participation in Community Outpatient Psychosocial Rehabilitation in Schizophrenia. Community Mental Health Journal 2010, 47: 622-627. PMID: 20676766, PMCID: PMC3046324, DOI: 10.1007/s10597-010-9343-z.Peer-Reviewed Original ResearchConceptsLower verbal fluency scoresVerbal fluency scoresSchizoaffective disorderPsychosocial rehabilitation programsVerbal learningVerbal abilityNeurocognitive factorsVisual vigilanceVerbal fluencyFluency scoresNeurocognitive assessmentDSM-IV schizophreniaSymptom measuresPsychosocial rehabilitationPredictors of participationDemographic variablesSchizophreniaFinal multivariate modelRehabilitation programGreater likelihoodRace/ethnicityStudy entryFluencyDisordersMeasures
2007
Absence of Significant Interactive Effects of High‐Dose d‐Cycloserine and Ethanol in Healthy Human Subjects: Preliminary Insights Into Ethanol Actions at the GlycineB Site of NMDA Glutamate Receptors
Trevisan L, Petrakis IL, Pittman B, Gueorguieva R, D’Souza D, Perry E, Limoncelli D, Krystal JH. Absence of Significant Interactive Effects of High‐Dose d‐Cycloserine and Ethanol in Healthy Human Subjects: Preliminary Insights Into Ethanol Actions at the GlycineB Site of NMDA Glutamate Receptors. Alcohol Clinical And Experimental Research 2007, 32: 36-42. PMID: 18028532, DOI: 10.1111/j.1530-0277.2007.00543.x.Peer-Reviewed Original ResearchConceptsCo-agonist siteHealthy human subjectsEthanol administrationD-cycloserineHigh-dose d-cycloserineAlcohol levelsReceptor functionPlacebo 4 hoursDouble-blind conditionsNMDA receptor functionNMDA glutamate receptorsMild sedative effectDoses of ethanolGlutamate receptor functionBreath alcohol levelsHuman subjectsVerbal fluencyGlycineB siteGroups of subjectsEthanol antagonismCombination of ethanolSedative effectsNMDA receptorsClinical significanceGlutamate receptors
2006
Estradiol and Tryptophan Depletion Interact to Modulate Cognition in Menopausal Women
Amin Z, Gueorguieva R, Cappiello A, Czarkowski KA, Stiklus S, Anderson GM, Naftolin F, Epperson CN. Estradiol and Tryptophan Depletion Interact to Modulate Cognition in Menopausal Women. Neuropsychopharmacology 2006, 31: 2489-2497. PMID: 16760926, DOI: 10.1038/sj.npp.1301114.Peer-Reviewed Original ResearchConceptsVerbal memory performanceVerbal memory scoresPositive mood effectsVerbal memoryVisuospatial learningMemory performanceVerbal fluencyMemory scoresMood effectsEstrogen treatmentSubjects designCognitionTryptophan depletionMenopausal womenLittle researchSignificant interactionHealthy menopausal womenLast menstrual periodNonreproductive behaviorsInteraction of estrogenActive TrPsOvarian steroidsMenstrual periodProtective effectFluency
2004
fMRI language task panel improves determination of language dominance
Gaillard WD, Balsamo L, Xu B, McKinney C, Papero PH, Weinstein S, Conry J, Pearl PL, Sachs B, Sato S, Vezina LG, Frattali C, Theodore WH. fMRI language task panel improves determination of language dominance. Neurology 2004, 63: 1403-1408. PMID: 15505156, DOI: 10.1212/01.wnl.0000141852.65175.a7.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingCerebral CortexCerebrovascular CirculationChildDominance, CerebralEpilepsyFemaleHumansLanguageLanguage TestsMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsPreoperative CareReproducibility of ResultsSpeech PerceptionTemporal LobeVerbal BehaviorConceptsIntracarotid amobarbital testPanel of tasksLanguage dominanceSingle taskEpilepsy patientsFMRI language paradigmsHemisphere language dominancePatients ages 12Temporal lobe epilepsyPartial epilepsy patientsPresurgical epilepsy patientsAuditory comprehensionFMRI taskVerbal fluencyLanguage tasksLanguage lateralityBilateral activationLanguage lateralizationT fMRILanguage areasNondiagnostic findingsLobe epilepsyAmobarbital testLanguage paradigmsSingle paradigmThe Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis
D'Souza DC, Perry E, MacDougall L, Ammerman Y, Cooper T, Wu YT, Braley G, Gueorguieva R, Krystal JH. The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis. Neuropsychopharmacology 2004, 29: 1558-1572. PMID: 15173844, DOI: 10.1038/sj.npp.1300496.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnxietyArousalAttentionBehaviorCognitionDose-Response Relationship, DrugDouble-Blind MethodDronabinolFemaleHallucinogensHemodynamicsHumansHydrocortisoneInjections, IntravenousMaleMemory, Short-TermMental RecallPanicProlactinPsychiatric Status Rating ScalesPsychometricsPsychoses, Substance-InducedSpeechVerbal LearningConceptsCannabinoid receptor functionWord recallRecognition recallVerbal fluencyCognitive deficitsProspective safety dataNegative symptomsAbuse disordersHealthy individualsCounterbalanced studyMonths poststudyRecallPsychotomimetic effectsPsychotic disordersReceptor functionPsychosisEndogenous psychosesIndividualsDistractibilityFluencyTransient symptomsDisordersEndocrine effectsSafety dataAnxiety
2003
Developmental aspects of language processing: fMRI of verbal fluency in children and adults
Gaillard WD, Sachs BC, Whitnah JR, Ahmad Z, Balsamo LM, Petrella JR, Braniecki SH, McKinney CM, Hunter K, Xu B, Grandin CB. Developmental aspects of language processing: fMRI of verbal fluency in children and adults. Human Brain Mapping 2003, 18: 176-185. PMID: 12599275, PMCID: PMC6871939, DOI: 10.1002/hbm.10091.Peer-Reviewed Original ResearchConceptsLaterality of activationSemantic verbal fluencyVerbal fluencyFluency taskFrontal gyrusSemantic verbal fluency taskInferior frontal gyrusSemantic fluency taskVerbal fluency taskMiddle frontal gyrusTask testingDevelopmental differencesLanguage processingFluencyBrain areasDevelopmental aspectsAge 7 yearsFMRIInterest approachBOLD fMRISPM 99GyrusActivation mapsChildrenAdults
1995
Can digit symbol-verbal fluency comparisons facilitate detection of pseudodementia?
Hawkins K, Sledge W, Orleans J, Quinlan D, Rakfeldt J, Hoffman R. Can digit symbol-verbal fluency comparisons facilitate detection of pseudodementia? European Archives Of Psychiatry And Clinical Neuroscience 1995, 244: 317-319. PMID: 7772615, DOI: 10.1007/bf02190410.Peer-Reviewed Original Research
1994
Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans: Psychotomimetic, Perceptual, Cognitive, and Neuroendocrine Responses
Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB, Charney DS. Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans: Psychotomimetic, Perceptual, Cognitive, and Neuroendocrine Responses. JAMA Psychiatry 1994, 51: 199-214. PMID: 8122957, DOI: 10.1001/archpsyc.1994.03950030035004.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood PressureCognitionDissociative DisordersDose-Response Relationship, DrugDouble-Blind MethodFemaleFrontal LobeHomovanillic AcidHumansHydrocortisoneKetamineMaleMethoxyhydroxyphenylglycolNeuropsychological TestsPerceptionProlactinPsychiatric Status Rating ScalesPsychoses, Substance-InducedPulseReceptors, N-Methyl-D-AspartateSchizophreniaSchizophrenic PsychologyConceptsWisconsin Card Sorting TestCard Sorting TestMini-Mental State ExaminationSorting TestNegative symptomsTests of vigilanceVerbal fluency taskDissociative statesState ExaminationFrontal cortical dysfunctionPsychosis Proneness ScalesClinician-Administered Dissociative States ScaleWord recallImmediate recallVerbal fluencyFluency taskVigilance taskCognitive deficitsCognitive functionRecallState scaleBrief Psychiatric Rating ScaleCortical dysfunctionTest dayPsychiatric Rating Scale
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