2012
Ontogenetic differences in ethanol's motivational properties during infancy
Nizhnikov M, Pautassi R, Varlinskaya E, Rahmani P, Spear N. Ontogenetic differences in ethanol's motivational properties during infancy. Alcohol 2012, 46: 225-234. PMID: 22440692, PMCID: PMC3376757, DOI: 10.1016/j.alcohol.2011.09.026.Peer-Reviewed Original ResearchConceptsKappa-opioid agonistRat pupsOpioid agonistsHigh dosesAppetitive propertiesAversive propertiesAppetitive reinforcementDose of ethanolDoses of ethanolMotivational propertiesPercent body weight gainBody weight gainTaste conditioning procedureEthanol's motivational propertiesAdult rodentsEarly infancyYoung ratsBody weightInfant ratsOld pupsLow dosesWeight gainPupsDosesAppetitive responses
2010
Analgesic Effects of Ethanol Are Influenced by Family History of Alcoholism and Neuroticism
Ralevski E, Perrino A, Acampora G, Koretski J, Limoncelli D, Petrakis I. Analgesic Effects of Ethanol Are Influenced by Family History of Alcoholism and Neuroticism. Alcohol Clinical And Experimental Research 2010, 34: 1433-1441. PMID: 20497133, PMCID: PMC9136640, DOI: 10.1111/j.1530-0277.2010.01228.x.Peer-Reviewed Original ResearchConceptsFamily historyAnalgesic responseHigh N scoresAnalgesic effectNoxious electrical stimulationPositive family historyStart of infusionDoses of ethanolSeparate test daysNegative family historyTest dayExperience of painN scoreMore analgesiaPlacebo dayPain assessmentPersonality traitsIntravenous administrationHealthy subjectsEthanol challengeLow doseElectrical stimulationAlcoholismThirty-oneLow N scores
2007
Absence of Significant Interactive Effects of High‐Dose d‐Cycloserine and Ethanol in Healthy Human Subjects: Preliminary Insights Into Ethanol Actions at the GlycineB Site of NMDA Glutamate Receptors
Trevisan L, Petrakis IL, Pittman B, Gueorguieva R, D’Souza D, Perry E, Limoncelli D, Krystal JH. Absence of Significant Interactive Effects of High‐Dose d‐Cycloserine and Ethanol in Healthy Human Subjects: Preliminary Insights Into Ethanol Actions at the GlycineB Site of NMDA Glutamate Receptors. Alcohol Clinical And Experimental Research 2007, 32: 36-42. PMID: 18028532, DOI: 10.1111/j.1530-0277.2007.00543.x.Peer-Reviewed Original ResearchConceptsCo-agonist siteHealthy human subjectsEthanol administrationD-cycloserineHigh-dose d-cycloserineAlcohol levelsReceptor functionPlacebo 4 hoursDouble-blind conditionsNMDA receptor functionNMDA glutamate receptorsMild sedative effectDoses of ethanolGlutamate receptor functionBreath alcohol levelsHuman subjectsVerbal fluencyGlycineB siteGroups of subjectsEthanol antagonismCombination of ethanolSedative effectsNMDA receptorsClinical significanceGlutamate receptors
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