2025
Religious Service Attendance, COVID-19 Vaccine Attitudes, and COVID-19 Vaccination Status: A Vaccine Safety Datalink Member Survey, 2022–2023
Williams J, Kurlandsky K, Breslin K, Cruz H, Stein A, Shoup J, Reifler L, Daley M, Lewin B, Goddard K, Henninger M, Nelson J, Vazquez-Benitez G, Hanson K, Fuller C, Hambidge S. Religious Service Attendance, COVID-19 Vaccine Attitudes, and COVID-19 Vaccination Status: A Vaccine Safety Datalink Member Survey, 2022–2023. AJPM Focus 2025, 4: 100404. PMID: 40977997, PMCID: PMC12446675, DOI: 10.1016/j.focus.2025.100404.Peer-Reviewed Original ResearchReligious service attendanceCenters for Disease Control and PreventionDisease Control and PreventionService attendanceControl and PreventionIntersection of religionCOVID-19 public health emergencyMultivariate logistic regressionPublic health emergencyCommunity partnershipsVaccine attitudesDisease preventionMember surveyCOVID-19Logistic regressionReport associationsAttendancePublic healthMethodological limitationsHealth emergencyCOVID-19 vaccine informationVaccine informationVaccination statusCOVID-19 pandemicPregnancy statusThe efficacy of lithium in the treatment of suicidal ideation, behavior and suicide: An updated systematic review and meta-analysis of randomized controlled trials
Wang J, Le G, Wong S, Teopiz K, Kwan A, Rosenblat J, Rhee T, Ho R, Lo H, Goldberg J, Vinberg M, Grande I, Mansur R, Meyer J, McIntyre R. The efficacy of lithium in the treatment of suicidal ideation, behavior and suicide: An updated systematic review and meta-analysis of randomized controlled trials. Journal Of Affective Disorders 2025, 387: 119487. PMID: 40441661, DOI: 10.1016/j.jad.2025.119487.Peer-Reviewed Original ResearchConceptsSuicidal ideationBipolar disorderSuicide attemptsCompleted SuicideTreatment of suicidal ideationTreating acute maniaRate of completed suicideAnti-suicidal effectsEfficacy of lithiumAcute maniaDiagnostic heterogeneityBD-I.Randomized Controlled TrialsTreatment fidelitySuicide measuresLithium effectsSuicideIdeationLithium levelsMethodological limitationsAssociated with nonsignificant reductionsMeta-analysis of randomized controlled trialsControlled TrialsFirst-line treatmentMeta-analysisAn App a Day will (Probably Not) Keep the Doctor Away: An Evidence Audit of Health and Medical Apps Available on the Apple App Store
Morley J, Laitila J, Ross J, Schamroth J, Zhang J, Floridi L. An App a Day will (Probably Not) Keep the Doctor Away: An Evidence Audit of Health and Medical Apps Available on the Apple App Store. Minds And Machines 2025, 35: 11. DOI: 10.1007/s11023-025-09710-7.Peer-Reviewed Original ResearchQuality of evidenceHealth appsApple App StorePurposive samplingApp StoreEvidence-based appsHealth app marketOverall quality of evidenceSample of appsLow-quality evidenceEvidence-based medicineRisk of harmOverall qualityMental healthEffectiveness claimsEvidence qualityHealthcare systemMedical appsApp's effectivenessEvidence baseHealthPublic healthMethodological limitationsPoor qualityClaims of effectiveness
2024
The revival of psilocybin between scientific excitement, evidence of efficacy, and real-world challenges
Scala M, Fabbri C, Fusar-Poli P, Di Lorenzo G, Ferrara M, Amerio A, Fusar-Poli L, Pichiecchio A, Asteggiano C, Menchetti M, De Ronchi D, Sub-Project M, Fanelli G, Serretti A. The revival of psilocybin between scientific excitement, evidence of efficacy, and real-world challenges. CNS Spectrums 2024, 29: 570-584. PMID: 39655426, DOI: 10.1017/s1092852924002268.Peer-Reviewed Original ResearchAnxiety disordersPost-traumatic stress disorderPsychedelic-Assisted PsychotherapyObsessive-compulsive disorderSubstance use disordersPsychotic spectrumStandard antidepressantsResearch to clinical practiceTreating moodStress disorderAddictive behaviorsPsychopharmacological researchPsychiatric conditionsPsilocybinEvidence of efficacyAnxietyMethodological limitationsDisordersMoodMethodological constraintsMethodological rigorEvidence basePotential paradigm shiftLong-term efficacyCultural stigmaA Systematic Review Evaluating PTSD Treatment Effects on Intermediate Phenotypes of PTSD
Palmisano A, Meshberg-Cohen S, Petrakis I, Sofuoglu M. A Systematic Review Evaluating PTSD Treatment Effects on Intermediate Phenotypes of PTSD. Psychological Trauma Theory Research Practice And Policy 2024, 16: 768-783. PMID: 36595460, DOI: 10.1037/tra0001410.Peer-Reviewed Original ResearchPosttraumatic stress disorderBehavioral treatment outcomesEvidence-based treatmentsCognitive controlThreat processingBody of researchPTSD outcomesPTSD treatmentPaucity of researchStress disorderPreliminary supportIntermediate phenotypesTreatment dropoutMethodological limitationsStudy limitationsTreatment effectsCurrent researchTreatment approachesStrong conclusionsNovel treatment approachesEmpirical studyTreatment outcomesTreatment efficacyResearchMemory
2023
Structural Neuroimaging of Hippocampus and Amygdala Subregions in Posttraumatic Stress Disorder: A Scoping Review
Ben-Zion Z, Korem N, Fine N, Katz S, Siddhanta M, Funaro M, Duek O, Spiller T, Danböck S, Levy I, Harpaz-Rotem I. Structural Neuroimaging of Hippocampus and Amygdala Subregions in Posttraumatic Stress Disorder: A Scoping Review. Biological Psychiatry Global Open Science 2023, 4: 120-134. PMID: 38298789, PMCID: PMC10829655, DOI: 10.1016/j.bpsgos.2023.07.001.Peer-Reviewed Original ResearchPost-traumatic stress disorderAmygdala subregionsStress disorderKey limbic regionsEtiology of PTSDPosttraumatic stress disorderDentate gyrusLimbic regionsSubiculum volumeSubregion volumesHippocampal subregionsDisorder pathogenesisStructural neuroimagingAutomatic segmentation softwareAmygdalar subregionsHippocampusNucleus volumeScoping ReviewPathogenesisCurrent literatureDisordersSegmentation softwareMethodological limitationsPost-traumatic psychopathologyReviewBrain imaging after cardiac arrest
Beekman R, Hirsch K. Brain imaging after cardiac arrest. Current Opinion In Critical Care 2023, 29: 192-198. PMID: 37078612, DOI: 10.1097/mcc.0000000000001032.Peer-Reviewed Original ResearchConceptsCardiac arrestComputed tomographyLong-term neurological outcomeQuantitative analysis of CTPrediction of long-term neurologic outcomeInterpretation of CTAnalysis of CTInterpreting CTBrain imagingNovel imaging techniquesNeurological outcomePoor outcomeDisorders of consciousnessNeurological injuryLack of specificityMRIInter-rater reliabilityQuantitative image analysisArrestOutcomesImaging techniquesBrainMultimodal assessmentMethodological limitationsPatients
2022
Inclusion and reporting of sex, gender, and race/ethnicity in randomized controlled trials of nonpharmacological treatments for alcohol use disorder: A meta‐epidemiologic review
Schick M, Nalven T, Lynch‐Gadaleta B, Hostetler K, Crawford M, Spillane N. Inclusion and reporting of sex, gender, and race/ethnicity in randomized controlled trials of nonpharmacological treatments for alcohol use disorder: A meta‐epidemiologic review. Alcohol Clinical And Experimental Research 2022, 46: 1154-1165. PMID: 35904527, DOI: 10.1111/acer.14850.Peer-Reviewed Original ResearchConceptsAlcohol use disorderTrials of nonpharmacologic treatmentsRacial/ethnic groupsRacial/ethnic breakdownConsequences of alcohol use disordersMinoritized racial/ethnic groupsNonpharmacological treatmentsGeneralizability of study findingsMental health diagnosesNational Institutes of Health Revitalization ActPreferred Reporting ItemsAUD treatmentInclusion of diverse groupsSex/gender groupUse disorderPsychological functioningPublished randomized controlled trialsRandomized Controlled TrialsHealth diagnosisReporting ItemsMethodological limitationsReporting of dataRacial/ethnic compositionSystematic reviewTreatment outcomesDemographic and clinical characteristics of lithium‐treated older adults with bipolar disorder
Forlenza OV, Hajek T, Almeida OP, Beunders AJM, Blumberg HP, Briggs FBS, De‐Paula V, Dols A, Eyler LT, Forester BP, Gildengers A, Jimenez E, Korten NCM, Lafer B, McWhinney SR, Mulsant B, Rej S, Sarna K, Schouws S, Sutherland A, Tsai S, Vieta E, Yala J, Sajatovic M, initiative G. Demographic and clinical characteristics of lithium‐treated older adults with bipolar disorder. Acta Psychiatrica Scandinavica 2022, 146: 442-455. PMID: 35837985, PMCID: PMC9588573, DOI: 10.1111/acps.13474.Peer-Reviewed Original ResearchConceptsLithium usersBipolar disorderClinical characteristicsOlder adultsDepression Rating ScaleCross-sectional analysisGlobal cognitive stateCardiovascular comorbiditiesCross-sectional approachClinical profileMood stabilizersLithium therapySevere depressionPsychiatric diagnosisRating ScaleCurrent prescriptionGlobal AGEingDisordersRapid cyclingAdultsRelevant differencesSafety concernsLower scoresCurrent useMethodological limitations
2021
Parental Age and the Risk for Alzheimer’s Disease in Offspring: Systematic Review and Meta-Analysis
Szejko N, Macul Ferreira de Barros P, Avila-Quintero VJ, Lombroso A, Bloch MH. Parental Age and the Risk for Alzheimer’s Disease in Offspring: Systematic Review and Meta-Analysis. Dementia And Geriatric Cognitive Disorders Extra 2021, 11: 140-150. PMID: 34178019, PMCID: PMC8216010, DOI: 10.1159/000515523.Peer-Reviewed Original ResearchAlzheimer's diseaseSystematic reviewParental ageRisk factorsPaternal ageRisk of ADLate Alzheimer's diseaseAdequate control groupsCohort studyPotential confoundersCommon causeCase controlControl groupElectronic databasesMeta-analysisVersion 16Significant associationDown syndromeDifferential riskDiseaseRelevant studiesAgeOlder parentsRiskMethodological limitationsSignal Detection and Methodological Limitations in a Real-World Registry: Learnings from the Evaluation of Long-Term Safety Analyses in PSOLAR
Bissonnette R, Gottlieb A, Langley R, Leonardi C, Papp K, Pariser D, Uy J, Lafferty K, Langholff W, Fakharzadeh S, Berlin J, Brouwer E, Greenspan A, Strober B. Signal Detection and Methodological Limitations in a Real-World Registry: Learnings from the Evaluation of Long-Term Safety Analyses in PSOLAR. Drug Safety 2021, 44: 699-709. PMID: 34075572, PMCID: PMC8184557, DOI: 10.1007/s40264-021-01065-z.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsHazard ratioIncident usersObservational studyCox model regression analysisAdjusted hazard ratioAdverse cardiovascular eventsReal-world registryInternational observational studyLong-term observational studyDisease-based registryRelevant clinical dataMACE riskUstekinumab exposureCardiovascular eventsPatient characteristicsPsoriasis patientsTreatment cohortsMethodological limitationsComparator groupSafety registryClinical dataRegistry dataModel regression analysisConclusionOur results
2020
Breastfeeding and the origins of health: Interdisciplinary perspectives and priorities
Azad MB, Nickel NC, Bode L, Brockway M, Brown A, Chambers C, Goldhammer C, Hinde K, McGuire M, Munblit D, Patel AL, Pérez‐Escamilla R, Rasmussen KM, Shenker N, Young BE, Zuccolo L. Breastfeeding and the origins of health: Interdisciplinary perspectives and priorities. Maternal And Child Nutrition 2020, 17: e13109. PMID: 33210456, PMCID: PMC7988860, DOI: 10.1111/mcn.13109.Peer-Reviewed Original ResearchConceptsHuman milkLow breastfeeding ratesEvidence-based benefitsPersonal breastfeeding experienceImplementation science approachHM feedingBreastfeeding ratesDonor milkMultidisciplinary panelBreastfeeding experienceHM compositionBreastfeedingComplexity of breastfeedingHealth practitionersOrigins of healthPopulation healthHealth effectsKnowledge translationMethodological limitationsPriority research areasMilkHealthCommunity partnershipsConflicts of interestAdvocacy efforts
2014
Behavioral and Neural Correlates of Executive Functioning in Musicians and Non-Musicians
Zuk J, Benjamin C, Kenyon A, Gaab N. Behavioral and Neural Correlates of Executive Functioning in Musicians and Non-Musicians. PLOS ONE 2014, 9: e99868. PMID: 24937544, PMCID: PMC4061064, DOI: 10.1371/journal.pone.0099868.Peer-Reviewed Original ResearchConceptsExecutive functionMusical trainingUntrained childrenEF skillsNeural correlatesVerbal fluencyConstruct of EFSMA/SMACognitive flexibilityEF batteryExecutive functioningAdult musiciansCognitive skillsCognitive capacityBrain activationRight VLPFCGreater activationProcessing speedAcademic achievementAcademic abilityRule representationEF regionFluencyMethodological limitationsMusiciansIs meditation associated with altered brain structure? A systematic review and meta-analysis of morphometric neuroimaging in meditation practitioners
Fox KC, Nijeboer S, Dixon ML, Floman JL, Ellamil M, Rumak SP, Sedlmeier P, Christoff K. Is meditation associated with altered brain structure? A systematic review and meta-analysis of morphometric neuroimaging in meditation practitioners. Neuroscience & Biobehavioral Reviews 2014, 43: 48-73. PMID: 24705269, DOI: 10.1016/j.neubiorev.2014.03.016.Peer-Reviewed Original ResearchConceptsAnatomical likelihood estimationAltered brain structureBrain structuresEffect sizeWhite matterSystematic reviewBrain regionsPublication biasInterhemispheric communicationBrain morphologyNeuroimaging studiesMemory consolidationBody awarenessInteroceptive body awarenessMethodological limitationsNumerous studiesFurther research
2008
Patient perspectives on communication with the medical team: Pilot study using the communication assessment tool-team (CAT-T)
Mercer L, Tanabe P, Pang P, Gisondi M, Courtney D, Engel K, Donlan S, Adams J, Makoul G. Patient perspectives on communication with the medical team: Pilot study using the communication assessment tool-team (CAT-T). Patient Education And Counseling 2008, 73: 220-223. PMID: 18703306, DOI: 10.1016/j.pec.2008.07.003.Peer-Reviewed Original ResearchConceptsEmergency departmentMedical teamPatient's perspectiveLevel 1 trauma centerPilot studyAdult ED patientsCross-sectional studyCommunication Assessment ToolHigh-quality patient careNon-English speakingED patientsTrauma centerPatient assessmentExclusion criteriaPatient experiencePatientsPsychiatric issuesPatient carePatients' ideasIndividual caregiversTeam-based settingsCommunication assessmentAssessment toolCareMethodological limitations
2000
Screening for Alcohol Problems in Primary Care: A Systematic Review
Fiellin DA, Reid MC, O'Connor PG. Screening for Alcohol Problems in Primary Care: A Systematic Review. JAMA Internal Medicine 2000, 160: 1977-1989. PMID: 10888972, DOI: 10.1001/archinte.160.13.1977.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestPrimary careAlcohol problemsFormal screening instrumentsAlcohol abuseHarmful drinkingScreening instrumentQuantity-frequency questionsPrimary care physiciansSearch of MEDLINEDisorders Identification TestCAGE questionsCare physiciansClinical subgroupsClinical measuresCriterion standardDiagnostic test researchSystematic reviewPatient spectrumDiagnostic testsMethodological standardsCareIdentification TestWorkup biasMethodological limitations
1989
Use of the Malleable Penile Prosthesis in the Treatment of Erectile Dysfunction: A Prospective Study of Postoperative Adjustment
Krauss D, Lantinga L, Carey M, Meisler A, Kelly C. Use of the Malleable Penile Prosthesis in the Treatment of Erectile Dysfunction: A Prospective Study of Postoperative Adjustment. Journal Of Urology 1989, 142: 988-991. PMID: 2795757, DOI: 10.1016/s0022-5347(17)38963-2.Peer-Reviewed Original ResearchConceptsPostoperative adjustmentPsychological adjustmentMethodological limitationsSexual desireLongitudinal studyAssessment proceduresImplant recipientsTreatment of erectile dysfunctionShort-term complicationsFrequency of sexual intercourseMalleable penile prosthesisProspective studyErectile dysfunctionFollowup periodPenile prosthesis
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