2025
Initiating Injectable Buprenorphine in People Hospitalized With Infections
Seval N, Roth P, Frank C, Di Paola A, Litwin A, Vander Wyk B, Neirinckx V, Schlossberg E, Lawson P, Strong M, Schade M, Nunez J, Levin F, Brady K, Nunes E, Springer S. Initiating Injectable Buprenorphine in People Hospitalized With Infections. JAMA Network Open 2025, 8: e2513000. PMID: 40445619, PMCID: PMC12125644, DOI: 10.1001/jamanetworkopen.2025.13000.Peer-Reviewed Original ResearchConceptsLong-acting buprenorphineOpioid use disorderReceipt of MOUDRandomized clinical trialsTAU armIntent-to-treat outcomesClinical trialsModerate to severe opioid use disorderSevere opioid use disorderProportion of patientsMultisite randomized clinical trialHospital settingStatistically significant differenceNursing case management servicesInfectious diseasesTAU groupMedian ageMedication management interventionCase management servicesInjectable buprenorphineHospitalization periodPrimary outcomeBaseline valuesInitiate MOUDMOUD receiptFunctional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study
Li R, Li J, Ji S, Li D, Chu L, Zhang J, Sun X, Luo X, Zhang Y. Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study. Neuropsychiatric Disease And Treatment 2025, 21: 115-128. PMID: 39882559, PMCID: PMC11776513, DOI: 10.2147/ndt.s502176.Peer-Reviewed Original ResearchYoung Mania Rating ScaleSerum brain-derived neurotrophic factorBrain-derived neurotrophic factorYoung Mania Rating Scale scoresBipolar disorderHDRS-17Functional remediationTrkB levelsEuthymic patientsConsensus Cognitive BatteryMania Rating ScaleEuthymic bipolar disorderEmotional Intelligence TestNo group differencesSerum BDNF levelsTyrosine kinase receptor BFR groupCognitive batteryAffective symptomsTreatment researchIntelligence testsTAU groupBDNF levelsMaze testCognitive function
2020
An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorder
Wexler BE, Vitulano LA, Moore C, Katsovich L, Smith SD, Rush C, Grantz H, Dong J, Leckman JF. An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorder. Psychological Medicine 2020, 51: 1524-1535. PMID: 32090720, DOI: 10.1017/s0033291720000288.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderExperimental medicine approachTAU groupMedicine approachHyperactivity disorderWeeks of treatmentCombined subtypeDiagnosis of ADHDClinical trial designHyperactive-impulsive subtypeAttention-deficit/hyperactivity disorderCross-over designDeficit hyperactivity disorderClinical improvementClinical symptomsRandomized crossCognitive dysfunctionCT groupPathophysiological heterogeneityCONSORT recommendationsTrial designResponse rateChange scoresSubtypesTargeted pathologyEffectiveness of enhanced cognitive behavior therapy for bulimia nervosa in Japan: a randomized controlled trial protocol
Ohara C, Sekiguchi A, Takakura S, Endo Y, Tamura N, Kikuchi H, Maruo K, Sugawara N, Hatano K, Kawanishi H, Funaba M, Sugawara A, Nohara N, Kawai K, Fukudo S, Sudo N, Cooper Z, Yoshiuchi K, Ando T. Effectiveness of enhanced cognitive behavior therapy for bulimia nervosa in Japan: a randomized controlled trial protocol. BioPsychoSocial Medicine 2020, 14: 2. PMID: 32123540, PMCID: PMC7041176, DOI: 10.1186/s13030-020-0174-z.Peer-Reviewed Original ResearchCognitive behavior therapyBody mass indexStart of treatmentBulimia nervosaBehavior therapyEffectiveness of CBTTreatment of BNDiagnosis of BNFifth Edition diagnosisWeeks of treatmentEnd of treatmentYears of ageDSM-5 criteriaSecondary outcomesMulticenter RCTPrimary outcomeMass indexFirst RCTRoutine treatmentTAU groupTrial protocolAdult outpatientsEdition diagnosisHigh prevalenceIntervention sites
2019
Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD
Smith SD, Crowley MJ, Ferrey A, Ramsey K, Wexler BE, Leckman JF, Sukhodolsky DG. Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD. Psychiatry Research 2019, 278: 248-257. PMID: 31233935, PMCID: PMC6637759, DOI: 10.1016/j.psychres.2019.06.021.Peer-Reviewed Original ResearchConceptsBehavioral measuresAttentional controlIntegrated brainGo/No-Go taskGo-P3 latencySlower reaction timesSocial interventionsRobust treatment effectAttentional systemADHD groupERP measuresDifference waveP3 latencyBrain activityADHDTAU groupEEG proceduresHealthy controlsHC groupReaction timeReplication purposesERPTreatment effectsChildrenSecondary goalCognitive behavioral rehabilitation for bipolar disorder patients: A randomized controlled trial
Gomes B, Rocca C, Belizario G, de B. F. Fernandes F, Valois I, Olmo G, Fachin R, Farhat L, Lafer B. Cognitive behavioral rehabilitation for bipolar disorder patients: A randomized controlled trial. Bipolar Disorders 2019, 21: 621-633. PMID: 31025470, DOI: 10.1111/bdi.12784.Peer-Reviewed Original ResearchConceptsCambridge Neuropsychological Test Automated BatteryBehavioral rehabilitationBipolar type IBipolar disorder patientsQuality of lifeImpaired cognitive domainsAssociated with cognitive impairmentCognitive rehabilitation interventionsWeekly group sessionsAdd-on treatmentBipolar disorderCognitive variablesDisorder patientsRandomized Controlled TrialsCognitive domainsVisual memoryTAU groupCognitive performanceQuality of life domainsCognitive impairmentEmotion recognitionLife outcomesFunctional impairmentQuality of life outcomesQuality of life scores
2014
Virtual Reality Job Interview Training for Individuals With Psychiatric Disabilities
Smith MJ, Ginger EJ, Wright M, Wright K, Humm L, Olsen D, Bell MD, Fleming MF. Virtual Reality Job Interview Training for Individuals With Psychiatric Disabilities. The Journal Of Nervous And Mental Disease 2014, 202: 659-667. PMID: 25099298, PMCID: PMC4149584, DOI: 10.1097/nmd.0000000000000187.Peer-Reviewed Original ResearchConceptsVirtual reality job interview trainingJob interview trainingJob interview skillsVR-JITInterview trainingInterview skillsRole-play performancePsychiatric disabilitiesCommunity-based settingsJob interviewsVirtual charactersTAU groupUsual groupFuture interviewsTraining sessionsFuture researchOnline trainingInitial feasibilityPerformance scoresSkillsTrainingParticipantsEfficacyDisabilityIndividuals
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