Initiating Injectable Buprenorphine in People Hospitalized With Infections
Seval N, Roth P, Frank C, Di Paola A, Litwin A, Vander Wyk B, Neirinckx V, Schlossberg E, Lawson P, Strong M, Schade M, Nunez J, Levin F, Brady K, Nunes E, Springer S. Initiating Injectable Buprenorphine in People Hospitalized With Infections. JAMA Network Open 2025, 8: e2513000. PMID: 40445619, PMCID: PMC12125644, DOI: 10.1001/jamanetworkopen.2025.13000.Peer-Reviewed Original ResearchConceptsLong-acting buprenorphineOpioid use disorderReceipt of MOUDRandomized clinical trialsTAU armIntent-to-treat outcomesClinical trialsModerate to severe opioid use disorderSevere opioid use disorderProportion of patientsMultisite randomized clinical trialHospital settingStatistically significant differenceNursing case management servicesInfectious diseasesTAU groupMedian ageMedication management interventionCase management servicesInjectable buprenorphineHospitalization periodPrimary outcomeBaseline valuesInitiate MOUDMOUD receipt
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