Yu Sun
Associate Research Scientist in NeuroscienceCards
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Research
Publications
2026
Machine learning-enabled design of MOF-based membranes for efficient C3H8-selective separation
Zhang Z, Wang M, Tian W, Cao X, Zhao M, Sun Y, Qiao Z. Machine learning-enabled design of MOF-based membranes for efficient C3H8-selective separation. Journal Of Membrane Science 2026, 745: 125244. DOI: 10.1016/j.memsci.2026.125244.Peer-Reviewed Original ResearchMOF-based membranesHigh-throughput computational screeningCoRE-MOFsComposite membranesSeparation performanceEfficient C3H6/C3H8 separationConfigurational-bias Monte Carlo simulationsNext-generation membranesC3H6/C3H8 separationGas separationMachine learningIL@MOFMOFSeparationGeometric criteriaPerformance evaluationML modelsHigh performanceHierarchical strategyComputer screenMachinePerformanceLong-Term PM2.5 Constituents Exposure, Genetic Susceptibility, and Incident Sleep Apnea: A Prospective Cohort Study
Yin G, Cui F, Chen N, Xing M, Zheng L, Tang L, Yuan L, Tian Y, Zhu Y, Sun Y. Long-Term PM2.5 Constituents Exposure, Genetic Susceptibility, and Incident Sleep Apnea: A Prospective Cohort Study. Chest 2026 PMID: 41833808, DOI: 10.1016/j.chest.2026.02.025.Peer-Reviewed Original ResearchLong-term exposure to PMPMExposure to PMInterquartile range increaseEuropean MonitoringRange increaseEmission controlSleep apneaSA riskHazard ratioUK Biobank participantsWHO guidelinesModel meteorologyObese individualsProspective cohort studyGenome-wide significant SNPsTime-dependent Cox regressionBiobank participantsUK Biobank databaseStratified analysisUrban populationCohort studyEscherichia coli CueO Efficiently Detoxifies Aflatoxin B1 via a Mediator-Enhanced Two-Step Mechanism
Chen Q, Huang J, Song C, Chen T, Wu X, Sun Y, Mu P, Deng Y, Wang L. Escherichia coli CueO Efficiently Detoxifies Aflatoxin B1 via a Mediator-Enhanced Two-Step Mechanism. Journal Of Agricultural And Food Chemistry 2026, 74: 9749-9760. PMID: 41811361, DOI: 10.1021/acs.jafc.5c13936.Peer-Reviewed Original ResearchPositively Charged Polymer‐Brush MOFs for Large‐Area, Pressure‐Resistant Gas Separation Membranes
Yang Y, Yuan Y, Sun Y, Shi F, Song C, Wang W, Li Q, Sheng M, Qiao Z, Hou J, Cheetham A, Wang Z. Positively Charged Polymer‐Brush MOFs for Large‐Area, Pressure‐Resistant Gas Separation Membranes. Advanced Materials 2026, e20099. PMID: 41789526, DOI: 10.1002/adma.202520099.Peer-Reviewed Original ResearchMixed matrix composite membranesMetal-organic frameworksMixed matrix membranesGas separation membranesSeparation membranesHigh-performance gas separation membranesScalable fabricationUltrathin selective layerRoll-to-roll productionGas separation technologyIndustrially relevant pressuresIndustrial implementationSpiral wound modulesMOF-basedMatrix membranesComposite membranesSelective layerDispersion instabilityIntegration of nanofillersSeparation performanceUncontrolled aggregationInterfacial defectsIndustrial translationGas purificationManufacturing conditionsPolymer-assisted monolithic MOFs formation towards membrane gas separation
Li D, Yang Z, Ao D, Xu Z, Yuan S, Meng F, Sun Y, Hou J, Qiao Z. Polymer-assisted monolithic MOFs formation towards membrane gas separation. Separation And Purification Technology 2026, 383: 136253. DOI: 10.1016/j.seppur.2025.136253.Peer-Reviewed Original ResearchMonolithic metal–organic frameworkMetal-organic frameworksMembrane gas separationGas separationExcellent gas separation performanceNon-selective defectsGas separation performanceTunable pore sizeMOF formationCO2/N2 separationStructural versatilityDiverse application potentialSeparation performanceHigh-pressure conditionsPore sizeCrystallinitySeparationApplication potentialPressure conditionsPorosityEngineering metal-organic framework nanochannels for enhanced air separation performance in composite membranes
Qin Z, Chen Y, Ye M, Sun Y, Zhang Z, Qiao Z. Engineering metal-organic framework nanochannels for enhanced air separation performance in composite membranes. Journal Of Membrane Science 2026, 741: 125076. DOI: 10.1016/j.memsci.2025.125076.Peer-Reviewed Original ResearchMetal-organic frameworksO2/N2 selectivityHofmann-type metal-organic frameworkDesign of metal-organic frameworksComposite membranesSeparation performanceO2 permeabilityMixed-ligand strategyMOF-based membranesO2/N2 separation performanceCombined DFT calculationsMolecular similarityMolecular sieving effectMembrane-based separationAir separation performanceDFT calculationsHofmann-typeO2/N2 separationPore apertureSieving effectSieving propertiesO2/N2Cryogenic distillationFeed pressureMolecular transportA global-scale framework for quantifying the gut microbiomeʼs mediating role in environmental and personal determinants of health
Yuan Y, Ou J, Fu X, Tang Y, Chen Y, Deng Q, Deng Y, Sun Y. A global-scale framework for quantifying the gut microbiomeʼs mediating role in environmental and personal determinants of health. Eco-Environment & Health 2026, 100236. DOI: 10.1016/j.eehl.2026.100236.Peer-Reviewed Original ResearchPersistent organic pollutantsExposure to persistent organic pollutantsAlpha diversityExposure to pollutantsGlobal-scale analysisProtective effect of vegetable consumptionGlobal burdenEffect of vegetable consumptionSelf-reported health outcomesGut microbiomeOrganic pollutantsDeterminants of healthBurden of environmental diseasesMicrobial indicesHigh diversityHealth risksGut diversityMediation analysisIrritable bowel syndromeEnvironmental characteristicsVegetable consumptionPersonal determinantsHealth outcomesHuman gut microbiomePollutionNovel LARS2 variants in patients with Perrault syndrome: expanding the genetic spectrum and phenotypic heterogeneity
Lin Z, Xiang J, Sun X, Shi X, Liu X, Cai Q, Yang J, Song N, Ye H, Xu J, Peng J, Ou X, Sun Y, Peng Z. Novel LARS2 variants in patients with Perrault syndrome: expanding the genetic spectrum and phenotypic heterogeneity. Frontiers In Genetics 2026, 17: 1785502. PMID: 41783587, PMCID: PMC12956261, DOI: 10.3389/fgene.2026.1785502.Peer-Reviewed Original ResearchSensorineural hearing lossWhole-exome sequencingPerrault syndromeLARS2 variantsGenetic spectrumMitochondrial leucyl-tRNA synthetasePrimary ovarian insufficiencyConservation analysisEvolutionary conservation analysisPhenotypic heterogeneityLeucyl-tRNA synthetaseIn-frame deletionHearing lossGenotype-phenotype relationshipsAssociated with PSOvarian insufficiencyClinical variablesGenotype-phenotype correlationCanonical splicingACMG/AMP guidelinesMinigene assayRare autosomal recessive disorderPhenotypic dataSplicing effectProtein stabilityThe role of the nasal microbiome in linking ozone pollution to allergic rhinitis in children
Tang H, Du S, Tan Y, Su W, Niu Z, Sun J, Shao W, Fang X, Tang Z, Zhang D, Chen Z, Zhang Z, Shao J, Norback D, Sun Y, Fu X, Lv L, Zhao Z. The role of the nasal microbiome in linking ozone pollution to allergic rhinitis in children. Journal Of Hazardous Materials 2026, 505: 141475. PMID: 41707393, DOI: 10.1016/j.jhazmat.2026.141475.Peer-Reviewed Original ResearchConceptsAmbient O3A-diversityNasal microbiomeFunctional pathwaysMicrobial functional pathwaysNasal microbial communityCo-occurrence network analysisSteroid hormone biosynthesisKeystone taxaMicrobial communitiesHormone biosynthesisMicrobiome's roleMicrobiomeAmbient ozoneNetwork analysisPathwayChildhood ARCo-occurrencePotential roleTaxaAllergic rhinitisOzone pollutionEnvironmental managementBiosynthesisChildhood allergic rhinitisRe-evaluating gut microbiome signatures of post-antibiotic dietary fiber intake in a large adult cohort
Tang Y, Fu X, Sun Y. Re-evaluating gut microbiome signatures of post-antibiotic dietary fiber intake in a large adult cohort. BMC Research Notes 2026, 19: 124. PMID: 41691331, PMCID: PMC13011435, DOI: 10.1186/s13104-026-07708-7.Peer-Reviewed Original ResearchConceptsAmerican Gut ProjectGene sequence dataDifferentially abundant generaHigher alpha diversityBeta diversityCommensal ClostridiaSequence dataAlpha diversityAntibiotic exposureMicrobiome statesAbundant generaGut microbiomeMicrobial signaturesANCOM-BCPrecision nutrition strategiesUnder-characterizedBifidobacteriumLachnospiraHigh-fiber intakeGutDiversityFiber intakeMultivariate linear regressionGenusParabacteroides
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