Sunil Koundal
Research ScientistDownloadHi-Res Photo
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Contact Info
Yale School of Medicine
1 GILBERT ST, The anlyan center, N142
NEW HAVEN, Connecticut 06519
United States
About
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Titles
Research Scientist
Appointments
Anesthesiology
Research ScientistPrimary
Other Departments & Organizations
Education & Training
- Post Doctoral associate
- Yale School of Medicine (2020)
- PhD
- Panjab University, Biophysics (2017)
- MSc
- Delhi University, Biomedical Sciences (2010)
- BSc
- Himachal University, Biotechnology (2008)
Research
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Overview
Medical Research Interests
Magnetic Resonance Imaging; Nuclear Magnetic Resonance, Biomolecular
Public Health Interests
Aging; Biomarkers; Metabolism; Metabolomics
ORCID
0000-0003-3969-1091
Research at a Glance
Yale Co-Authors
Frequent collaborators of Sunil Koundal's published research.
Publications Timeline
A big-picture view of Sunil Koundal's research output by year.
Research Interests
Research topics Sunil Koundal is interested in exploring.
Helene Benveniste, MD, PhD
Hedok Lee
Former YSMZachary Gursky, PhD
Adam Joseph Kundishora
Former YSMBurhan Ozturk
Garrett Allington
Former YSM
17Publications
558Citations
Magnetic Resonance Imaging
Publications
2025
A novel gene edited rat model of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)
Monte B, Davis J, Zhu X, Xu F, Majchrzak M, Cabral M, Van Nostrand W, Healey B, Koundal S, Lee H, Robinson J, Benveniste H, Van Nostrand W. A novel gene edited rat model of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). Cerebral Circulation - Cognition And Behavior 2025, 9: 100401. PMID: 41142321, PMCID: PMC12546807, DOI: 10.1016/j.cccb.2025.100401.Peer-Reviewed Original ResearchCitationsAltmetricAge-dependent brain responses to mechanical stress determine resilience in a chronic lymphatic drainage impairment model
Gursky Z, Khan Z, Koundal S, Bhardwaj A, Melgarejo J, Xu K, Chen X, Lin H, Gu X, Lee H, Kipnis J, Dori Y, Tannenbaum A, Santambrogio L, Benveniste H. Age-dependent brain responses to mechanical stress determine resilience in a chronic lymphatic drainage impairment model. Journal Of Clinical Investigation 2025, 135: e182555. PMID: 40663395, PMCID: PMC12404751, DOI: 10.1172/jci182555.Peer-Reviewed Original ResearchCitationsAltmetric
2024
Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease
Koundal S, Chen X, Gursky Z, Lee H, Xu K, Liang F, Xie Z, Xu F, Lin H, Van Nostrand W, Gu X, Elkin R, Tannenbaum A, Benveniste H. Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease. IScience 2024, 27: 111463. PMID: 39720539, PMCID: PMC11667077, DOI: 10.1016/j.isci.2024.111463.Peer-Reviewed Original ResearchCitationsAltmetric
2023
Author Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries
Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand W, Benveniste H. Author Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries. Nature Aging 2023, 3: 1603-1603. PMID: 38001312, DOI: 10.1038/s43587-023-00544-5.Commentaries, Editorials and LettersCitationsAltmetricContinuous positive airway pressure (CPAP) increases CSF flow and glymphatic transport
Ozturk B, Koundal S, Al Bizri E, Chen X, Gursky Z, Dai F, Lim A, Heerdt P, Kipnis J, Tannenbaum A, Lee H, Benveniste H. Continuous positive airway pressure (CPAP) increases CSF flow and glymphatic transport. JCI Insight 2023, 8: e170270. PMID: 37159262, PMCID: PMC10371231, DOI: 10.1172/jci.insight.170270.Peer-Reviewed Original ResearchCitationsAltmetricThe choroid plexus links innate immunity to CSF dysregulation in hydrocephalus
Robert S, Reeves B, Kiziltug E, Duy P, Karimy J, Mansuri M, Marlier A, Allington G, Greenberg A, DeSpenza T, Singh A, Zeng X, Mekbib K, Kundishora A, Nelson-Williams C, Hao L, Zhang J, Lam T, Wilson R, Butler W, Diluna M, Feinberg P, Schafer D, Movahedi K, Tannenbaum A, Koundal S, Chen X, Benveniste H, Limbrick D, Schiff S, Carter B, Gunel M, Simard J, Lifton R, Alper S, Delpire E, Kahle K. The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus. Cell 2023, 186: 764-785.e21. PMID: 36803604, PMCID: PMC10069664, DOI: 10.1016/j.cell.2023.01.017.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling
Lee H, Ozturk B, Stringer MS, Koundal S, MacIntosh BJ, Rothman D, Benveniste H. Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling. NeuroImage 2022, 261: 119512. PMID: 35882269, PMCID: PMC9969358, DOI: 10.1016/j.neuroimage.2022.119512.Peer-Reviewed Original ResearchCitationsCharacterization of perivascular space pathology in a rat model of cerebral small vessel disease by in vivo magnetic resonance imaging
Monte B, Constantinou S, Koundal S, Lee H, Dai F, Gursky Z, Van Nostrand WE, Darbinyan A, Zlokovic BV, Wardlaw J, Benveniste H. Characterization of perivascular space pathology in a rat model of cerebral small vessel disease by in vivo magnetic resonance imaging. Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism 2022, 42: 1813-1826. PMID: 35673963, PMCID: PMC9536121, DOI: 10.1177/0271678x221105668.Peer-Reviewed Original ResearchCitationsAltmetricStudies on metabolic alterations due to hypobaric hypoxia in serum using NMR spectroscopy
Koundal S, Gandhi S, Khushu S. Studies on metabolic alterations due to hypobaric hypoxia in serum using NMR spectroscopy. Biomarkers 2022, 27: 562-567. PMID: 35532034, DOI: 10.1080/1354750x.2022.2076152.Peer-Reviewed Original ResearchCitationsBlockade of lymphatic drainage to deep cervical lymph nodes impacts CSF flow and brain morphometry
Koundal S, Gursky Z, Chen X, Lee H, Santambrogio L, Kipnis J, Tannenbaum A, Benveniste H. Blockade of lymphatic drainage to deep cervical lymph nodes impacts CSF flow and brain morphometry. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2022 DOI: 10.58530/2022/4377.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
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Honors
honor Travel grant
09/17/2024Other Award American College of NeuropsychopharmacologyDetailsUnited Stateshonor Magna Cum Laude Award
05/16/2019International AwardInternational Society for Magnetic Resonance in MedicineDetailsCanada
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Mailing Address
Yale School of Medicine
1 GILBERT ST, The anlyan center, N142
NEW HAVEN, Connecticut 06519
United States