Skip to Main Content

INFORMATION FOR

    Stephen Baldassarri, MD, MHS

    Assistant Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine)
    DownloadHi-Res Photo

    Are You a Patient?

    View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.

    View Doctor Profile

    About

    Titles

    Assistant Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine)

    Appointments

    Education & Training

    MHS
    Yale University (2018)
    MD
    Boston University School of Medicine (2009)
    BA
    Williams College (2005)

    Research

    Overview

    Medical Research Interests

    Acute Lung Injury; Addiction Medicine; Critical Care; Electronic Nicotine Delivery Systems; Internal Medicine; Marijuana Use; Neuroimaging; Neurosciences; Nicotine; Opioid-Related Disorders; Psychopharmacology; Pulmonary Medicine; Sleep; Tobacco Use Disorder

    Research at a Glance

    Research Interests

    Research topics Stephen Baldassarri is interested in exploring.

    Publications

    2024

    2020

    2019

    2017

    Clinical Trials

    Current Trials

    Academic Achievements & Community Involvement

    • honor

      NIDA K23 Career Development Award

    • honor

      Iva Dostanic Physician-Scientist Award

    • honor

      NIDA K12 Drug Use, Addiction, and HIV Research Scholars

    Clinical Care

    Overview

    Stephen Baldassarri, MD, specializes in treating patients who are critically ill, have acute or chronic pulmonary diseases, and those with addiction to nicotine and tobacco products. He collaborates closely with the Smilow Cancer Hospital’s Tobacco Treatment Service, which treats adult patients struggling with nicotine addiction and smoking cessation, and, in some cases, patients who vape with e-cigarettes.

    “Acute respiratory failure is something that needs to be quickly diagnosed and decisively treated,” Dr. Baldassarri says. “It’s important to identify what’s causing the problem—which can be anything from infections, heart failure, environmental exposures (including smoking or drug use), among many other causes.”

    Often patients with acute respiratory failure need assistance from a ventilator or tight-fitting face mask, which are therapies designed to provide breathing support. The faster a patient receives a diagnosis, the quicker a treatment plan can be implemented, Dr. Baldassarri explains, allowing them to recover and breathe on their own sooner. When someone requires a ventilator to breathe for a prolonged period of time, the powerful muscles in the diaphragm and chest wall can start to weaken rapidly. “If a person develops significant muscle weakness, it can complicate their recovery from respiratory failure,” he says. “Early efforts to optimize physical strength and nutrition and minimize time spent on a ventilator are key treatment components to promote recovery from critical illness.”

    The opportunity to treat critically ill patients has appealed to Dr. Baldassarri’s desire to help patients and their families, and his innate interest in medicine and science. “Critical care medicine involves caring for patients holistically, with attention to mind and body as a whole, and also thinking about each organ system in detail. It also involves substantial care, attention, and support of the patient’s family members,” he says.

    When he connects with patients and their family members, Dr. Baldassarri focuses on being mindful and present. “In this age of distraction, maintaining focused attention is really important, and I try to put myself in their shoes, listen, and be empathetic,” he says. “Giving someone your time and undivided attention means a lot.”

    In addition to treating patients, Dr. Baldassarri dedicates time to research in drug addiction, especially in the context of nicotine. One area of research includes understanding factors that influence nicotine delivery to the brain from e-cigarette devices. “We know that the speed of delivery of any drug has a major impact on how addictive the drug can be. Drugs that reach the brain faster tend to have a higher abuse liability,” he says.

    Clinical Specialties

    Pulmonary Critical Care ; Internal Medicine; Addiction Medicine

    Board Certifications

    • Addiction Medicine (Preventive Medicine)

      Certification Organization
      AB of Preventive Medicine
      Original Certification Date
      2020
    • Critical Care Medicine (Internal Medicine)

      Certification Organization
      AB of Internal Medicine
      Latest Certification Date
      2024
      Original Certification Date
      2016
    • Pulmonary Disease

      Certification Organization
      AB of Internal Medicine
      Latest Certification Date
      2024
      Original Certification Date
      2015
    • Internal Medicine

      Certification Organization
      AB of Internal Medicine
      Latest Certification Date
      2024
      Original Certification Date
      2012

    Yale Medicine News

    Get In Touch