Donald Wright, MD, MHS
Instructor of Emergency MedicineCards
About
Research
Publications
2025
Identifying Deprescribing Opportunities With Large Language Models in Older Adults: Retrospective Cohort Study.
Socrates V, Wright DS, Huang T, Fereydooni S, Dien C, Chi L, Albano J, Patterson B, Sasidhar Kanaparthy N, Wright CX, Loza A, Chartash D, Iscoe M, Taylor RA. Identifying Deprescribing Opportunities With Large Language Models in Older Adults: Retrospective Cohort Study. JMIR Aging 2025, 8: e69504. PMID: 40215480, DOI: 10.2196/69504.Peer-Reviewed Original ResearchAutomated computation of the HEART score with the GPT-4 large language model.
Wright DS, Socrates V, Huang T, Safranek CW, Sangal RB, Dilip M, Boivin Z, Srica N, Wright CX, Feher A, Miller EJ, Chartash D, Taylor RA. Automated computation of the HEART score with the GPT-4 large language model. Am J Emerg Med 2025, 93: 120-125. PMID: 40184662, DOI: 10.1016/j.ajem.2025.03.065.Peer-Reviewed Original ResearchQuantitative valve motion assessment in adolescents using point-of-care ultrasound: short communication
Riera A, Chen L, Wright D, Leviter J. Quantitative valve motion assessment in adolescents using point-of-care ultrasound: short communication. The Ultrasound Journal 2025, 17: 11. PMID: 39847270, PMCID: PMC11757829, DOI: 10.1186/s13089-025-00402-y.Peer-Reviewed Original ResearchTricuspid annular plane systolic excursionE-point septal separationPoint-of-care ultrasoundAnnular plane systolic excursionRight ventricular systolic functionPediatric emergency departmentAbnormal vital signsCross-sectional studyVentricular systolic functionBody mass indexUnpaired t-testM-mode measurementsEmergency departmentSystolic excursionAnthropometric dataSystolic functionCardiopulmonary complaintsNo significant correlationMass indexPsychiatric illnessMental statusPearson correlationExclusion criteriaSeptal separationMotion assessment
2024
Leveraging artificial intelligence to reduce diagnostic errors in emergency medicine: Challenges, opportunities, and future directions
Taylor R, Sangal R, Smith M, Haimovich A, Rodman A, Iscoe M, Pavuluri S, Rose C, Janke A, Wright D, Socrates V, Declan A. Leveraging artificial intelligence to reduce diagnostic errors in emergency medicine: Challenges, opportunities, and future directions. Academic Emergency Medicine 2024, 32: 327-339. PMID: 39676165, PMCID: PMC11921089, DOI: 10.1111/acem.15066.Peer-Reviewed Original ResearchClinical decision supportEmergency departmentArtificial intelligencePatient safetyDiagnostic errorsImplementing AIImprove patient safetyClinical decision support systemsEnhance patient outcomesReducing diagnostic errorsLeverage artificial intelligenceEmergency medicineHealth careTargeted educationReduce cognitive loadQuality improvementEmergency cliniciansData retrievalReal-time insightsDecision supportPatient outcomesCognitive overloadInformation-gathering processPatient detailsCliniciansHigh-Sensitivity Troponin: Finding a Meaningful Delta
Wright C, Wright D, Hu J, Gallegos C. High-Sensitivity Troponin: Finding a Meaningful Delta. Journal Of Cardiovascular Development And Disease 2024, 11: 318. PMID: 39452288, PMCID: PMC11508916, DOI: 10.3390/jcdd11100318.Peer-Reviewed Original ResearchEuropean Society of CardiologyHs-cTnCardiac biomarkersMyocardial injuryFourth Universal Definition of Myocardial InfarctionHigh-sensitivity cardiac troponinUniversal Definition of Myocardial InfarctionChest pain syndromeAmerican College of Cardiology/American Heart AssociationHs-cTn assaysHs-cTn valuesFourth Universal DefinitionDefinition of myocardial infarctionClinical risk scoreAcute myocardial injurySociety of CardiologyStandard cardiac biomarkersInterpretation of dynamic changesChest painPain syndromeOptimal time frameCardiac troponinRule-outHeart AssociationSymptom onsetAssociation Between Exercise Program Participation and Hospitalization of Older Adults
Wright D, Zhou B, Wright C, Axtell R, Mangi A, Safdar B. Association Between Exercise Program Participation and Hospitalization of Older Adults. American Journal Of Preventive Medicine 2024, 68: 83-90. PMID: 39218409, DOI: 10.1016/j.amepre.2024.08.017.Peer-Reviewed Original ResearchExercise program participationNon-participantsPersonalized exercise programProgram participantsBaseline physical assessmentNational mortality databaseAssociated with decreased riskCox proportional hazards modelsExercise programAll-cause hospitalizationsMortality DatabaseProportional hazards modelRetrospective cohort studyExercise centersOlder AdultsPhysical assessmentHospital dataCohort studySustained participationDecreased hospitalizationBaseline measurementsHazards modelAssess sexMeasures of fitnessHospitalPatient-Representing Population's Perceptions of GPT-Generated Versus Standard Emergency Department Discharge Instructions: Randomized Blind Survey Assessment
Huang T, Safranek C, Socrates V, Chartash D, Wright D, Dilip M, Sangal R, Taylor R. Patient-Representing Population's Perceptions of GPT-Generated Versus Standard Emergency Department Discharge Instructions: Randomized Blind Survey Assessment. Journal Of Medical Internet Research 2024, 26: e60336. PMID: 39094112, PMCID: PMC11329854, DOI: 10.2196/60336.Peer-Reviewed Original ResearchPatient factors associated with unplanned sedation after intra-articular lidocaine for shoulder dislocation
Wright D, Sherak R, Seo L, Parhar A, Baloescu C, Patient factors associated with unplanned sedation after intra-articular lidocaine for shoulder dislocation, JEM Reports, Volume 3, Issue 2, 2024, 100093Peer-Reviewed Original ResearchAutomated HEART score determination via ChatGPT: Honing a framework for iterative prompt development
Safranek C, Huang T, Wright D, Wright C, Socrates V, Sangal R, Iscoe M, Chartash D, Taylor R. Automated HEART score determination via ChatGPT: Honing a framework for iterative prompt development. Journal Of The American College Of Emergency Physicians Open 2024, 5: e13133. PMID: 38481520, PMCID: PMC10936537, DOI: 10.1002/emp2.13133.Peer-Reviewed Original ResearchPrompt designsChest pain evaluationRule-based logicScore determinationLanguage modelPrivacy safeguardsPrompt improvementExtract insightsPain evaluationClinical notesRate of responseDiagnostic performancePhysician assessmentPrompt testingDetermination of heartChatGPTDesign frameworkNote analysisHeartSubscoresSimulated patientsClinical spaceEmergency Physician-performed Echocardiogram in Non-ST Elevation Acute Coronary Syndrome Patients Requiring Coronary Intervention
Tan T, Wright D, Baloescu C, Lee S, Moore C. Emergency Physician-performed Echocardiogram in Non-ST Elevation Acute Coronary Syndrome Patients Requiring Coronary Intervention. Western Journal Of Emergency Medicine 2024, 0: 9-16. PMID: 38205979, PMCID: PMC10777186, DOI: 10.5811/westjem.60508.Peer-Reviewed Original ResearchConceptsPresence of RWMARegional wall motion abnormalitiesCoronary interventionEmergency departmentEmergency physiciansElevation acute coronary syndrome patientsNew regional wall motion abnormalitiesNon-ST elevation acute coronary syndrome patientsAcute coronary syndrome patientsRetrospective observational cohort studyEarly coronary interventionDiagnostic coronary angiographyCoronary artery bypassCoronary syndrome patientsObservational cohort studyActivation criteriaIdentification of patientsWall motion abnormalitiesCare transthoracic echocardiographyMeeting inclusion criteriaED electrocardiogramArtery bypassSame admissionAdult patientsCohort study