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Keith Choate, MD, PhD

Professor of Dermatology, Pathology, and Genetics; Director of Research, Dermatology

Contact Information

Keith Choate, MD, PhD

Patient Care Location

Mailing Address

  • Dermatology

    PO Box 208059, 333 Cedar Street

    New Haven, CT, 06520-8059

    United States



Keith Choate M.D., Ph.D., is a physician-scientist who employs tools of human genetics to understand fundamental mechanisms of disease. In clinical practice, he specializes in complex cases unresponsive to standard therapies. Dr. Choate is an attending physician at Yale-New Haven Hospital, the Yale Primary Care Center, and Yale Dermatology Associates. He is the co-chief of Dermatology at the Saint Raphael's Campus of Yale-New Haven Hospital.

Dr. Choate provides care for patients with all dermatologic conditions and he has special interest in:

  • atopic dermatitis (eczema)
  • autoimmune blistering disorders including pemphigus and bullous pemphigoid
  • inflammatory disorders such as lichen planus, pityriasis rubra pilaris, and severe acne
  • genetic disorders including disorders of keratinization, and cutaneous mosaic disorders
  • psoriasis
  • skin cancer

Dr. Choate uses a wide variety of treatment modalities including phototherapy, systemic immunosuppressive agents, retinoids, and newer disease-targeted biologic agents to treat psoriasis and atopic dermatitis (eczema).

Patients are seen in consultation after referral by a dermatologist or primary care physician, typically after first-line therapies have failed.

In his research, Dr. Choate employs next generation sequencing technologies to identify mutations causing genetic skin diseases and his group studies the function of identified genes in normal and disease states. Dr. Choate has published over 30 peer-reviewed articles and chapters and presents his work at national and international meetings. He is a member of the Medical and Scientific Advisory Board for the Foundation for Ichthyosis and Related Skin types. His laboratory is funded by the National Institute of Arthritis and of Musculoskeletal and Skin Diseases, a division of the National Institutes of Health.

Dr. Choate mentors undergraduate, graduate, and medical students in his laboratory, teaches at Yale Medical School, and trains resident physicians and fellows.

Education & Training

  • MD
    Yale University School of Medicine (2004)
  • PhD
    Yale University, Cell Biology (2001)
  • MPhil
    Yale University, Cell Biology (2000)
  • BS
    Stanford University, Biological Sciences (1995)
  • Postdoctoral Fellow
    Yale University School of Medicine
  • Resident
    Yale- New Haven Hospital
  • Intern
    Yale-New Haven Hospital
  • Board Certification
    AB of Dermatology, Dermatology (2008)

Honors & Recognition

AwardAwarding OrganizationDate
ADAAmerican Dermatological Association2017
ASCIAmerican Society for Clinical Investigation2016
Young Investigator AwardAmerican Academy of Dermatology2011
Alpha Omega AlphaAlpha Omega Alpha2004

Professional Service

Associate Director Yale Medical Scientist Training Program2015 - 2017
Associate Editor, British Journal of Dermatology2015 - 2017
Board of Directors, Foundation for Ichthyosis and Related Skin Types2015 - 2017
Basic Science Exam Committee, American Board of Dermatology2012 - 2017
Medical and Scientific Advisory Board, Foundation for Ichthyosis and Related Skin Types2010 - 2017

Departments & Organizations