Computational Immunology
Computational immunology (or systems immunology) involves the development and application of bioinformatics methods, mathematical models and statistical techniques for the study of immune system biology. The immune system is composed of dozens of different cell types and hundreds of intersecting molecular pathways and signals. Systems approaches can be used to predict how the immune system will respond to a particular infection or vaccination. Or it can help understand how best to design an immunotherapy -- will it help ease disease and what might the side effects be? In addition, computational approaches are increasingly vital to understand the implications of the wealth of gene expression and epigenomics data being gathered from immune cells. Yale has a diverse research program in computational immunology that brings together expertise from a variety of scientific disciplines to bear on research projects in vaccine response, host-pathogen dynamics, cell-fate choices, immune genomics, informatics, and many other topics. Students interested in computational immunology can be co-mentored by faculty from the Immunology and Computational Biology and Bioinformatics Tracks.
Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology; Paul B. Beeson Professor of Medicine; Program Director, Investigative Medicine
Waldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis; Section Chief, Infectious Diseases
Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute
William S. and Lois Stiles Edgerly Professor of Neurology and Professor of Immunobiology; Chair, Department of Neurology; Neurologist-in-Chief, Yale New Haven Hospital
Waldemar Von Zedtwitz Professor of Immunobiology and Molecular, Cellular and Developmental Biology and Professor of Epidemiology (Microbial Diseases); Professor of Molecular Cellular and Developmental Biology; Investigator, Howard Hughes Medical Institute
Professor; Co-Director of Graduate Studies, Computational Biology and Bioinformatics
Associate Professor of Microbial Pathogenesis and of Immunobiology; Member, Yale Systems Biology Institute; Investigator, Howard Hughes Medical Institute
Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute
Arthur H. and Isabel Bunker Professor of Medicine (Hematology) and Professor of Immunobiology; Director, Center of Molecular and Cellular Oncology
Waldemar Von Zedtwitz Professor of Microbial Pathogenesis and of Immunobiology and Director of Biological and Biomedical Sciences (BBS); Vice-Chair, Department of Microbial Pathogenesis
Associate Professor of Neurology; Academic Chief, Division of Stroke and Vascular Neurology, Neurology
Waldemar Von Zedtwitz Professor of Immunobiology and Professor of Molecular Biophysics and Biochemistry; Chair of Immunobiology