Stephanie Samples O'Malley, PhD

Professor of Psychiatry; Director, Division of Substance Abuse Research in Psychiatry; Deputy Chair, Clinical Research

Research Interests

Psychiatry and Psychology

Research Organizations

Cancer Prevention and Control

Cancer Prevention and Control

Psychiatry: Addictions, Division of | Center for Nicotine and Tobacco Use Research at Yale (CENTURY) | Center for the Translational Neuroscience of Alcoholism | Psychology Section | Psychotherapy Development Center | Smoking Cessation and Alcohol Treatment Research Clinic | Stress & Addiction Clinical Research Program | Substance Abuse Research | Women's Behavioral Health Research, Division of | Yale Tobacco Center of Regulatory Science

Research Summary

The goal of our laboratory is to develop more efficacious treatments for alcohol use disorders and nicotine dependence and to provide the science base for the regulation of tobacco products. Toward this end, we are conducting clinical trials to determine efficacy of medications and behavioral interventions, and laboratory studies to determine the mechanisms underlying the effects of treatment and the underlying nature of the disorder. Research on how flavors, such as methol and sweeteners, influence the use of tobacco products is underway to inform the regulation of tobacco products by the FDA.

Extensive Research Description

Yale Tobacco Center for Regulatory Science

Clinical trials of varenicline for the treatment of alcohol dependence among smokers and of naltrexone for young adult heavy drinkers

Laboratory studies to evaluate medications for substance use disorders

Validation of biomarkers for monitoring drinking in clinical trials

Secondary analyses to identify moderators and predictors of response to treatments for alcohol dependence using tree based and trajectory analyses

Training of clinician and transdisciplinary scientists

Selected Publications

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Contact Info

Stephanie Samples O'Malley, PhD
Office Location
Connecticut Mental Health Center
34 Park Street, Ste SAC 202

New Haven, CT 06519
Mailing Address
Connecticut Mental Health Center - SAC 202
34 Park Street

New Haven, CT 06508