The Tobacco Research in Youth (TRY) group is a team of researchers, led by Dr. Suchitra Krishnan-Sarin, in Yale's School of Medicine dedicated to developing and disseminating the optimal intervention for adolescent tobacco users. We aim to discover the best behavioral and pharmacological combination to enhance quit rates among high-school aged students. We have been working with over 20 high schools in CT to develop and disseminate information on the prevalence of tobacco and other substance use among youth, and develop and disseminate prevention and cessation programs. Our current work is tackling the essential task of understanding and reducing tobacco, including e-cigarette, use among youth. Our first goal is aimed at both preventing and helping with cessation of tobacco use among high school students. For more information about E-Cigarette Cessation, click here. Our second goal is to develop tools to measure e-cigarette withdrawal among high school youth, as withdrawal is an important barrier to quitting, but there is limited understanding of youth e-cigarette withdrawal and how it impacts youth ability to quit. For more information about Understanding E-Cigarette Withdrawal Among Youth, click here. Our work also focuses on developing a comprehensive understanding of changes in tobacco and other substance use behaviors among high school youth. We conduct school-wide tobacco surveys in Connecticut schools to assess perceptions, rates of use, and risk factors for initiation. For more information about our School-wide Tobacco surveys, click here. We also provide most up-to-date evidence-based educational presentations to local schools/communities in an effort to educate students, parents, faculty, administrators, and community members about youth and vaping. For more information on our E-Cigarette Education and Prevention program, click here.