John H. Krystal, MD

Robert L. McNeil Jr. Professor of Translational Research; Chair, Department of Psychiatry; Chief of Psychiatry, Yale-New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism; Director, Clinical Neuroscience Division, VA National Center for PTSD; Director, VA Alcohol Research Center; Medical Director, Schizophrenia Biological Research Center, DVA

Departments & Organizations

NIMH Research Training Program in Childhood-onset Neuropsychiatric Disorders

Diabetes Endocrinology Research Center

Psychiatry: Center for the Translational Neuroscience of Alcoholism | VA Alcohol Research Center | NIAAA Center for the Translational Neuroscience of Alcoholism | VA National Center for PTSD


Research Interests

Neurobiology; pharmacotherapy; genetics; neuroimaging; schizophrenia; alcoholism; PTSD more...


Education

  • B.A., University of Chicago, 1980
  • M.D., Yale University, 1984

Selected Publications

  • Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J. Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry. 2011;70(6):528-36.
  • Krystal JH, Rosenheck RA, Cramer JA, Vessicchio JC, Jones KM, Vertrees JE, Horney RA, Huang GD, Stock C; Veterans Affairs Cooperative Study No. 504 Group. Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial. JAMA. 2011;306(5):493-502.
  • Rosenheck RA, Krystal JH, Lew R, Barnett PG, Fiore L, Valley D, Thwin SS, Vertrees JE, Liang MH; CSP555 Research Group. Long-acting risperidone and oral antipsychotics in unstable schizophrenia. N Engl J Med. 2011 Mar 3;364(9):842-51

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