John H. Krystal, MD

Robert L. McNeil, Jr. Professor of Psychiatry and Professor of Neuroscience; Chair, Department of Psychiatry; Chief of Psychiatry, Yale-New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism ; Director, Clinical Neuroscience Division, VA National Center for PTSD; Director, VA Alcohol Research Center; Medical Director, Schizophrenia Biological Research Center, DVA

Departments & Organizations

Psychiatry: Adult Psychiatry | Center for the Translational Neuroscience of Alcoholism | Clinical Neuroscience Research Unit | Obsessive Compulsive Disorder Research Clinic

Albert J. Solnit Integrated Training


Diabetes Research Center

Interdepartmental Neuroscience Program

LCME Institutional Self-Study Task Force: LCME Medical Students Subcommittee

Office of Student Research

Yale Medical Group

Office of Cooperative Research


Dr. Krystal is a leading expert in the areas of alcoholism, schizophrenia, and post-traumatic stress disorder. His work links psychopharmacology, neuroimaging, and molecular genetics to study the neurobiology and to develop novel treatments for these disorders.

He is a member of the U.S. National Academy of Medicine. He also serves in a variety of advisory and review capacities for NIAAA, NIMH, Wellcome Trust, Brain and Behavior Research Foundation, and the Karolinska Institutet.

He previously served on the National Alcohol Abuse and Alcoholism Advisory Council (NIAAA), the Department of Defense Psychological Health Advisory Committee, the NIMH Board of Scientific Counselors (chair, 2005-2007), American College of Neuropsychopharmacology (president, 2012), and International College of Neuropsychopharmacology (president-elect).

Dr. Krystal also edits the journal, Biological Psychiatry (impact factor: 10.255).

Education & Training

MD Yale University (1984)
BA University of Chicago, Behavioral Sciences (1980)
Residency Yale University School of Medicine

Honors & Recognition

  • Henri Begleiter Award for Research ExcellenceResearch Society on Alcoholism (2015)

  • Paul Hoch Research AwardAmerican Psychopathological Association (2014)

  • Exemplary Psychiatrist AwardNational Alliance on Mental Illness (2011)

  • MemberU.S. National Academy of Medicine (2010)

  • Jack Mendelson Award for Clinical ResearchNational Institute on Alcohol Abuse and Alcoholism (2010)

  • Stanley Dean Award for Schizophrenia ResearchAmerican College of Psychiatry (2010)

  • Anna-Monika Prize in Depression ResearchAnna-Monika Foundation, Munich, Germany (2009)

  • Kempf Award for Contributions to Schizophrenia Research through Research and MentorshipAmerican Psychiatric Association (2005)

  • Joel Elkes AwardAmerican College of Neuropsychopharmacology (2001)

Professional Service

  • President-Elect International College of Neuropsychopharmacology (2014 - 2016)

  • President American College of Neuropsychopharmacology (2011 - 2012)

International Activity

  • Schizophrenia Treatment Taichung, Taiwan (2013 - 2014)

    Consulting regarding novel treatments for schizophrenia and ketamine-related psychosis.

  • Neuroimaging studies of schizophrenia and related disorders Chengdu, China (2012 - 2014)

    Neuroimaging studies of brain structure and function associated with psychosis

  • Rapid Acting Antidepressant Treatment Taipei, Taiwan (2012 - 2014)

    Consulting to a study conducted evaluating the antidepressant effects of ketamine, led by Dr. Tung-Ping (Tom) Su.

  • Ketamine Psychosis Guangzhou, China (2010 - 2014)

    Studying the phenomenology and genetics of ketamine psychosis in relation to schizophrenia

  • Clinical Archives Project Cherite Hospital Berlin, Germany (2006 - 2014)

    The Department of Psychiatry at Cherite Hospital in Berlin has long been a home to ethical and compassionate treatment of patients. However, in the period leading up to World War II, its psychiatry leadership involved the hospital in the emerging eugenics movement. This work, contributed to the...

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