TCORS 1.0Project 1 - Effects of Flavors on Nicotine Choice and Central Reward Mechanisms
TCORS 2.0Project 1 - Effects of Sweet and Coolant Flavors on Nicotine Choice, Consumption and Seeking
TCORS 3.0Project 1 - Beyond Characterizing Flavors: Effects of Odorless Constituents (sensory additives, solvents, and synthetic nicotine) on Tobacco Product Use Behaviors from Adolescence to Adulthood
Core A - Administrative Core
The goal of the Administrative Core is to provide scientific and administrative oversight, quality control, and data management and statistical support, and communication and coordination for the Yale TCORS projects and pilots. The Core serves as a central resource for its component and pilot projects, as well as a resource for collaboration across the TCORS nationally. This framework provides an umbrella structure to facilitate the success of each project and to ensure that each project has impact within the Center that exceeds its value in isolation.
Core B – Career Enhancement Core
Tobacco regulatory science is a transdisciplinary area that requires depth and breadth of research expertise. The Career Enhancement Core supports the development of Scholars as independent tobacco regulatory scientists. Appointed Scholars will conduct mentored TRS research, participate in a formal online TRS course and a grant and professional development seminar and will be awarded pilot research grants that address the FDA TRS research priorities.
Core D – Laboratory and Analytical Core
The Laboratory Core aims to objectively determine tobacco use related compounds in biological samples, as well as to characterize and quantify additives to various tobacco products, i.e., non-biological samples. In addition, the Laboratory core leverages knowledge on tobacco product ingredients to support the creation of custom e-liquids for specific study applications.
Measurement and Analytics Core
The Measurement and Analytics Core (MAC) supports the Yale TCORS 3.0 by ensuring the use of validated measures and statistical procedures across projects and pilot studies to increase the scientific rigor, interpretability, and impact of findings. In addition, the MAC provides training in measurement, statistics, and the use of nationally representative data (i.e., The Population Assessment of Tobacco and Health Study [PATH]) to address Tobacco Regulatory Science research questions. Finally, the MAC develops novel, psychometrically sound measures and statistical approaches to address pressing needs in Tobacco Regulatory Science, with plans for widespread dissemination within the broader Tobacco Regulatory Science community and beyond.