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Project 1

Beyond Characterizing Flavors: Effects of Odorless Constituents (sensory additives, solvents, and synthetic nicotine) on Tobacco Product Use Behaviors from Adolescence to Adulthood

Project 1 will examine how odorless cooling additives, sweeteners, and sweet solvent/ humectants, as well as nicotine stereoisomers impact nicotine initiation, preference, reinforcement, and transitions in use from adolescence to adulthood.

Research Team

Project 2

Addictive Threshold of Nicotine and the Impact of Sweeteners

Project 2 will determine if thresholds for nicotine reinforcement, discrimination, and subjective rewarding effects differ among adults who smoke cigarettes and if these thresholds are altered by exposure to sweeteners.

Research Team

Project 3

Examining Appeal and Addiction Potential of Novel E-cigarette Constituents

Project 3 will determine how novel nicotine forms (synthetic nicotine) and novel flavor additives (synthetic coolants) impact e-cigarette appeal and addiction potential among adults who use e-cigarettes and combustible tobacco products.

Research Team

Project 4

Evaluating the Effects of E-cigarettes vs. Oral Nicotine Pouches and Product Constituents (menthol flavor, nicotine concentration) on Adult Cigarette Smoking and Addiction

Project 4 will model potential regulations of cooling flavors and nicotine concentrations in non-combustible tobacco products (nicotine pouches, e-cigarettes) and examine their impact on adult’s ability to switch from smoking cigarettes to using less harmful, non-combustible products.

Research Team