Leptin also influences brain cells that control appetite, Yale researchers find
Twenty years after the hormone leptin was found to regulate metabolism, appetite, and weight through brain cells called neurons, Yale School of Medicine researchers have found that the hormone also acts on other types of cells to control appetite.
Mother’s high-fat diet alters metabolism in offspring, leading to higher obesity risk
The offspring of obese mothers consuming a high-fat diet during pregnancy are at a higher risk than the children of thin mothers for lifelong obesity and related metabolic disorders. The molecular and cellular basis for these differences are clarified in a new study published in the Jan. 23 issue of Cell by researchers at Yale School of Medicine and the University of Cologne.
Key cellular mechanism in the body’s ‘battery’ can either spur or stop obesity
Becoming obese or remaining lean can depend on the dynamics of the mitochondria, the body’s energy-producing “battery,” according to two new studies by Yale School of Medicine researchers featured as the cover story in the Sept. 26 issue of the journal Cell.
Weight Gain in Early Adulthood and Long-term Obesity Linked with Endometrial Cancer Risk
Women who put on substantial weight in early adulthood were diagnosed with endometrial cancer at much younger ages than their peers who gained weight later in life, new research by the Yale School of Public Health has found.
Study Finds Excessive Weight Gain During Pregnancy, Inadequate Postpartum Weight Loss Among Low-Income, Minority Women
A new study by the Yale School of Public Health finds that excessive weight gain during pregnancy and inadequate postpartum weight loss are particularly prevalent among low-income, ethnic minority women.
Young, Overweight Women Found to Have Heightened Risk of STIs
Young, overweight women are at “significantly” heightened risk for sexually transmitted infections and are more likely to engage in risky sexual behaviors than their more slender peers, a new study by the Yale School of Public Health has found.
Small: Yale study may help resolve bitter debate over low-cal sweeteners
Several studies in recent years have reported that low-calorie sweeteners in foods and beverages disrupt the human metabolism, promoting the development of diabetes and obesity. But other studies have found that consuming low-calorie drinks and food has little impact on metabolism and might actually aid in weight loss. A new study by Yale researchers published March 3 in the journal Cell Metabolism may help reconcile these conflicting findings.
Molecular ‘Doormen’ Open the Way to Potential Obesity Treatment
In obese individuals, cellular "doormen" open the gates far too wide in certain key fat cells, known as visceral fat cells, letting in too many carbohydrates without first burning off lipids. This leads to a ballooning of the size of visceral fat cells in the belly.
Want to Lose Weight? You Don’t Have to Do It Alone
A new Yale weight loss center aims to provide the entire continuum of care for patients with obesity, as a growing body of evidence has shown that weight loss—be it surgical or nonsurgical—also prolongs life, restores mobility, and lowers the risks of cancer, heart disease, liver disease, and other serious illnesses. “You start to get an idea of what a burden obesity is when you relieve patients of that burden. They were affected, literally, from head to toe,” says John Morton, MD, MPH.Source: Yale Medicine
Maternal acetaminophen use during pregnancy tied to excess weight in girls
Girls born to mothers who frequently used acetaminophen while pregnant may be more likely to be overweight at age 11 years compared with girls whose mothers did not use acetaminophen while pregnant, according to findings published in Obesity.Source: Endocrine Today
Yale-led Study Reveals Biology of Leptin, the Hunger Hormone
In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and also suggest a potential strategy for developing future weight-loss treatments, they said.
Pain and modifiable risk factors among overweight veterans who seek to lose weight
Robin Masheb, PhD, Senior Research Scientist in Psychiatry and Director of the Veterans Initiative for Eating and Weight at the VA Connecticut Healthcare System, is the senior author of a paper published in Appetite that examines the relationship between pain and and modifiable risk factors among overweight veterans who seek to lose weight.
National Public Radio (NPR) live interview on Where We Live with David Deroches and Lydia Brown: America’s Diet Craving
National Public Radio (NPR) live interview on Where We Live with David Deroches and Lydia Brown: America’s Diet CravingSource: National Public Radio (NPR) live interview on Where We Live with David Deroches and Lydia Brown: America’s Diet Craving