The Immunology Laboratory is responsible for laboratory testing and clinical consultation in several broad areas including the evaluation of autoimmune disease, immunodeficiencies, immunoproliferative disorders, and allergy, as well as having responsibility for some aspects of infectious disease serology. Much work is carried out together with the Molecular Diagnostics, Microbiology, Virology and Hematology laboratories to provide seamless consultation and diagnostics for various clinical scenarios.
In the evaluation of immunodeficiency, whether congenital or as a result of transplantation, and especially in the clinical trial setting, the laboratory also works in concert with the Immune Monitoring Core Facility. The laboratory is responsible for testing that is at the cusp of the research to clinical arc – tests developed there often move into the full clinical arena.
The laboratory provides reference diagnostics for both IgE and IgG responses to the full complement of potential allergens, whether food, environmental, or other. State-of-the art methodologies are employed. Individualized 'panel' testing of allergens appropriate to specific geographic areas and/or patient populations can be requested by individual physicians and practices.
Immunoproliferative, Autoimmune, and Immunodeficiency Disorders
Optimized evaluation and followup of patients with immunoproliferative disorders, including plasma cell dyscrasias, is an area of interest to the clinical laboratory, including complete cryoglobulin evaluation. The laboratory also concentrates on providing maximally cost-effective testing for rheumatologic and other autoimmune conditions.