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Keck MS & Proteomics Resource Publications


213. Xue, M., Kim, C. S., Healy, A. R., Wernke, K. M., Wang, Z., Frischling, M. C., Shine, E. E., Wang, W., Herzon, S. B., Crawford, J. M. (2019) Structure elucidation of colibactin and its DNA cross-links. Science 365 (6457), (PCMID: PMC6820679).

212. Wilson, R. Rauniyar, N., Sakaue, F., Lam, T.K.T., Williams, K., Nairn, A. (2019) Development of targeted mass spectrometry-based approaches for quantitation of proteins enriched in the postsynaptic density (PSD), Proteomes Special Issue on Neuroproteomics 7(2), (PMCID:PMC6630806).

211. Torregrossa, M., MacDonald, M., Stone, K.L., Lam, T.K.T., Nairn, A.C., Taylor, J.R. (2019) Phosphoproteomic analysis of cocaine memory extinction and reconsolidation in the nucleus accumbens, Psychopharmacology 236(1), 531-543, (PMCID:PMC6374162).

210. Piersigilli, F., Lam, T. T., Vernocchi, P., Quagliariello, A., Putignani, L., Aghai, Z. H., Bhandari, V., (2019) Identification of new biomarkers of bronchopulmonary dysplasia using metabolomics. Metabolomics 15 (2), 20, (PMID: 30830433).

209. Peng, G., Wilson, R., Tang, Y., Lam, T. T., Nairn, A. C., Williams, K., Zhao, H. (2019) ProteomicsBrowser: MS/proteomics data visualization and investigation. Bioinformatics 35 (13), 2313-2314, (PCMID: PMC6596887).

208. Nassar, A. F., Wisnewski, A. V., Wu, T., Lam, T. T., King, I. Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma (2019) J. Chromatogr. Sci. 57 (3), 195-203, (PMID: 30395213).

207. Li, J., Walsh, A., Lam, T.K.T., Delecluse, H.J., El-Guindy, A. (2019) A single phosphoacceptor residue in BGLF3 is essential for transcription of Epstein-Barr virus late genes. PLoS pathogens 15(8), e1007980, (PMCID: PMC6713331).

206. Kiapour, A.M., Sieker, J.T., Proffen, B.L., Lam, T.K.T., Fleming, B.C., Murray, M.M. (2019) Synovial fluid proteome changes in ACL injury-induced posttraumatic osteoarthritis: Proteomics analysis of porcine knee synovial fluid. PloS One 14(3), e0212662, (PMCID: PMC6396923).

205. Ghosh, D., Egbuta, C., Kanyo, J.E., Lam, T.K.T.(2019) Phosphorylation of human placental aromatase CYP19A1. Biochemical Journal 476(21), 3313-3331, (PMCID: PMC7069221).

204. Farasyn, T., Crowe, A., Hatley, O., Neuhoff, S., Alam, K., Kanyo, J., Lam, T.K.T., Ding, K., Yue, W. (2019).Preincubation with everolimus and sirolimus reduces organic anion-transporting polypeptide (OATP) 1B1-and 1B3-mediated transport independently of mTOR kinase inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions. Journal of Pharmaceutical Sciences 108(1), 3443-3456, (PMCID: PMC6759397).

203. Charkoftaki, G., Thompson, D.C., Golla, J.P., Garcia-Milian, R., Lam, T.T., Engel, J.,Vasilou, V. (2019) Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells. Chemico-biological Interactions 304, 88-96, (PMCID: PMC7988342).

202. Rauniyar, N., Yu, X. Cantley, J., Voss, E.Z., Belcher, J., Colangelo, C.M., Stone, K.L., Dahl, N., Parikh, C., Lam, T.T., Cantley, L.G. (2018) Quantification of urinary protein biomarkers of autosomal dominant polycystic kidney disease by parallel reaction monitoring. Proteomics Clin. Appl. 12(5), e1700157, (PMCID: PMC6736530).

201. Rao, V., Zavala, G., Roy, A., Mains, R., Eipper, B. (2018) A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells. J. Cellular Physiology 234(6), 8683-8697, (PMCID: PMC6395498).

200. Miller, M.B., Wilson, R.S., Lam, T.T., Nairn, A. C., Picciotto, M.R. (2018) Evaluation of the phosphoproteome of mouse alpha 4/beta 2-containing nicotinic acetylcholine receptors in vitro and in vivo. Proteomes 6(4), 42, (PMCID: PMC6313896).

199. Mervosh, N., Wilson, R., Rauniyar, N., Hofford, R., Kutlu, M., Calipari, E., Lam, T. T., Kiraly, D., (2018) Granulocyte-colony stimulating factor alters the proteomic landscape of the ventral tegmental area. Proteomes Special Issue on Neuroproteomics 6(4), 35, (PMCID: PMC6313867).

198. Luxmi, R., Blaby-Haas, C., Kumar, D., Rauniyar, N., King, S., Mains, R., Eipper, B. (2018) Proteases shape the Chlamydomonas secretome: Comparison to classical neuropeptide processing machinery. Proteomes Special Issue on Neuroproteomics 6(4), 36 (PMCID: PMC6313938).

197. Li, D., Musante, V., Zhou, W., Picciotto, M.R., Nairn, A.C. (2018) Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. J. Biol. Chem. 293(28),11179-11194 (PMCID: PMC6052221).

196. Goel, R.K., Meyer, M., Paczkowska, M., Reimand, J., Vizeacoumar,F., Lam, T.K., Lukong, K.E. (2018) Global phosphoproteomic analysis identifies SRMS-regulated secondary signaling intermediates. Proteome Science 16(1),16 (PMCID: PMC6098843).

195. Cijsouw, T., Ramsey, A., Lam, T., Carbone, B., Blanpied, T., Biederer, T. (2018) Mapping the proteome of the synaptic cleft through proximity labeling reveals new cleft proteins. Proteomes Special Issue on Neuroproteomics 6(4), 48 (PMCID: PMC6313906).

194. Carlyle, B.C., Kitchen, R.R., Zhang, J., Wilson, R., Lam, T.T., Rozowsky, J.S., Williams, K., Sestan, N., Gerstein, M.B., Nairn, A.C. (2018) Isoform level interpretation of high-throughput proteomic data enabled by deep integration with RNA-seq. J. Proteome Research 17(10), 3431-3444, (PMCID:PMC6392456).

193. Bian, X., Saheki, Y., and De Camilli, P. (2018) Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport. EMBO J. 37(2), 219-234 (PMCID: PMC5770786),

192. Bertholomey, M.L., Stone, K.L., Lam, T.T., Bang, S., Wu, W., Nairn, A.C., Taylor, J.R., Torregrossa, M.M. (2018) Phosphoproteomic analysis of the amygdala response to adolescent glucocorticoid exposure reveals G-protein coupled receptor kinase 2 (GRK2) as a target for reducing motivation for alcohol. Proteomes Special Issue on Neuroproteomics 6(4), 41, (PMCID: PMC6313880).

191. Yuan, Q., Ren, C., Xu, W., Petri, B., Zhang, J., Zhang, Y., Kubes, P., Wu, D., Tang, W. (2017) PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury. Cell Reports 19, 2586-2597. (PMCID: PMC5548392).

190. Williams, K., Colangelo, C., Hou, L., Chung, L., Belcher, J., Abbott, T., Hall, I., Zhao, H., Cantley, J., Parikh, C. (2017) Use of a Targeted Urine Proteome Assay (TUPA) to Identify Protein Biomarkers of Delayed Recovery After Kidney Transplant. Proteomics Clinical Applications 11, 7-8, (PMCID: PMC5549272).

189. Srivastava, R., Mannam, P., Rauniyar, N., Lam, T.K.T., Luo, R., Lee, P.J., Srivastava, A. (2017) Proteomics data on MAP Kinase Kinase 3 knock out bone marrow derived macrophages exposed to cigarette smoke extract. Data in Brief 13, 320-325, (PMCID: PMC5476452).

188. Rauniyar, N., Peng, G., Lam, T., Zhao, H., Mor, G., Williams, K., (2017) Data-Independent Acquisition (DIA) and Parallel Reaction Monitoring (PRM) Mass Spectrometry Identification of Serum Biomarkers for Ovarian Cancer. Biomarkers Insight 12, 1-12, (PMCID: PMC5462478).

187. Musante, V., Li L., Kanyo, J., Lam, T.T., Colangelo, C.M., Cheng, S.K., Brody, H., Greengard, P., Le Novère N., Nairn, A.C. (2017) Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. eLife 6, e24998, (PMCID:PMC5515580).

186. Miller, M.B., Yan, Y., Machida, K., Kiraly, D.D., Levy, A.D., Wu, Y.I., Lam, T.T., Abbott, T., Koleske, A.J., Eipper, B.A., Mains, R.E. (2017) Brain region and isoform-specific phosphorylation alters Kalirin SH2 domain interaction sites and calpain sensitivity, ACS Chemical Neuroscience 8, 1554-1569, (PMCID: PMC5517348).

185. Li, X., Tao, Y., Murphy, J.W., Scherer, A.N., Lam, T.K.T., Marshall, A.G., Koleske, A.J., Boggon, T.J. (2017) The repeat region of cortactin is intrinsically disordered in solution. Scientific reports 7(1), 1-10, (PMCID: PMC5711941).

184. Janostiak, R., Rauniyar, N., Lam, T.K.T., Ou, J., Zhu, L.J., Green, M.R., Wajapeyee, N. (2017) MELK promotes melanoma growth by stimulating the NF-κB pathway. Cell Reports 21(10), 2829-2841, (PMCID: PMC5726781).

183. Goffredo, M., Santoro, N.,Tricò, D., Giannini, C., D’Adamo, E., Zhao, H., Peng, G., Yu, X., Lam, T.K.T., Pierpont, B., Caprio, S., Herzog, R. (2017) A branched-chain amino acid-related metabolic signature characterizes obese adolescents with non-alcoholic fatty liver disease. Nutrients 9(7), 642 (PMCID: PMC5537762).

182. Glass, L.N., Swapna, G., Chavadi, S.S.,Tufariello, J.A.M.,Mi, K., Drumm, J.E., Lam, T.K.T., Zhu, G., Zhan, C., Vilchéze, C., Arcos, J., Chen, Y., Bi, L., Mehta S., Porcelli, S.A., Almo, S.C., Yeh, S., Jacobs, W.R.,Torrelles J.B., Chan, J., (2017) Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth. PLoS pathogens 13(7), e1006515, (

181. Carlyle, B., Kitchen, R., Kanyo J., Voss, E., Pletikos, M., Lam, T. T., Gerstein, M., Sestan, N., Nairn, A.C. (2017) A multiregional proteomic survey of the postnatal human brain, Nature Neuroscience 20, 1787-1795, (PMCID: PMC5894337).

180. Andrade, E.C., Musante, V., Horiuchi, A., Matsuzaki, H., Harrison, A., Brody, H., Wu, T., Greengard, P., Taylor, J.R. and Nairn, A.C. (2017) ARPP-16 is a striatal-enriched inhibitor of protein phosphatase 2A regulated by microtubule-associated serine/threonine kinase 3 (Mast 3 kinase). J. Neurosci. 37(10), 2709-2722 (PMCID: PMC5354324)

179. Vishwanatha, K.S., Back, N., Lam, T.K.T., Mains, R.E., Eipper, B.A. (2016) O-Glycosylation of a Secretory Granule Membrane Enzyme Is Essential for Its Endocytic Trafficking. J. Biol. Chem. 291(18), 9835-50. (PMCID: PMC4850319).

178. Rich, M.T., Abbott, T., Chung, L., Gulcicek E.E., Stone, K.L., Colangelo, C.M., Lam, T.T., Nairn, A.C., Taylor, J.R., Torregrossa, M.M. (2016) Phosphoproteomic analysis reveals a novel mechanism of CAMKIIα regulation inversely induced by cocaine memory extinction versus reconsolidation. J. Neuroscience 36(29),7613-27, (PMCID: PMC4951572).

177. McClure-Begley, T. D., Esterlis, I., Stone, K. L., Lam, T. T., Grady, S.R., Colangelo, C.M., Lindstrom, J.M., Marks, M.J., and Picciotto, M.R. (2016) Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex. eNeuro 3, (PMCID: PMC4985585).

176. Henderson, M.X., Wirak, G.S., Zhang, Y., Dai, F., Ginsberg, S.D., Dolzhanskaya, N., Staropoli, J.F., Nijssen, P.C.G., Lam, TuKiet T., Roth, A.F., Davis, N.G., Dawson, G., Velinov, M., Chandra, S.S., (2016) Neuronal ceroid lipofuscinosis with DNAJC5/CSPalpha mutation has PPT1 pathology and exhibit aberrant protein palmitoylation. Acta Neuropathologics 131(4), 621-37 (PMCID: PMC4791186).

175. Fleming, M.R., Brown, M.R., Kronengold, J., Zhang, Y., Jenkins, D.P., Barcia, G., Nabbout, R., Bausch, A.E., Ruth, P., Lukowski, R., Navaratnam, D.S. and Kaczmarek, L.K. (2016) Stimulation of Slack K+ channels alters mass at the plasma membrane by triggering disassociation of a phosphatase-regulatory complex. Cell Reports 16, 2281-2288, (PMCID: PMC5123741).

174. Cantley, L., Colangelo, C., Stone, K., Chung, L., Belcher, J., Abbott, T., Cantley, J., Williams, K., and Parikh, C. (2016) Development of a Targeted Urine Proteome Assay for Kidney Diseases. Proteomics Clinical Applications 10, 58-74, (PMCID: PMC5003777).

173. Engmann, O., Giralt, A., Gervasi, N., Marion-Poll, L., Gasmi, L., Filhol, O., Picciotto, M.R., Gilligan, D., Greengard, P., Nairn, A.C., Hervé, D., Girault, J.A. (2015) DARPP-32 interaction with adducin may mediate rapid environment effects on striatal neurons. Nat. Commun. 6, (PMCID: PMC4675091).

172. Colangelo, C., Shifman, M., Cheung, K., Stone, K.L., Carriero, N., Gulcicek, E., Lam, T.T., Wu, T., Bjornson, R.D., Bruce, C., Nairn, A.C., Rinehart, J., Miller, P.L., and Williams, K. (2015) YPED: An integrated bioinformatics suite and database for mass spectrometry based proteomics research. Genomics, Proteomics, and Bioinformatics 13(1), 25-35, (PMCID: PMC4411476).

171. Colangelo, C., Ivosev, G., Chung, L., Abbott, T., Shifman, M., Sakaue, F., Cox, D., Kitchen, R., Burton, L., Tate, S., Gulcicek, E., Bonner, R., Rinehart, J., Nairn, A., and Williams, K. (2015) Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins. Proteomics 15, 1202-1214, (PMCID: PMC4698340).

170. Shibata, S., Arroyo, J.P., Castañeda-Bueno, M., Puthumana, J., Zhang, J., Uchida, S., Stone, K.L., Lam, T.T., Lifton, R.P. (2014) Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation. Proc. Natl. Acad. Sci. U S A. 111(43),15556-61, (PMCID: PMC4217463).

169. Ma, X.M., Miller, M.B., Vishwanatha, K.S., Gross, M., Wang, Y., Abbott, T., Lam, T.T., Mains, R.E., Eipper, B.A. (2014) Non-enzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl. Mol. Biol. Cell 25(9),1458-71 (PMCID: PMC4004595).

168. Tellez, L. A., Medina, S., Han, W., Ferreira, J. G., Licona-Limon, P., Ren, X., Lam, T. T., Schwartz, G. J., and de Araujo, I. E. (2013) A gut lipid messenger links excess dietary fat to dopamine deficiency. Science 341, 800-802. (PMID: 23950538)

167. Shibata, S., Zhang, J., Puthumana, J., Stone, K. L., and Lifton, R. P. (2013) Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc. Natl. Acad. Sci. U. S. A. 110, 7838-7843, (PMCID: PMC3651502).

166. Robison, A. J., Vialou, V., Mazei-Robison, M., Feng, J., Kourrich, S., Collins, M., Wee, S., Koob, G., Turecki, G., Neve, R., Thomas, M., and Nestler, E. J. (2013) Behavioral and structural responses to chronic cocaine require a feedforward loop involving DeltaFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell. J Neurosci. 33, 4295-4307, (PMCID: PMC3658178).

165. McClure-Begley, T. D., Stone, K. L., Marks, M. J., Grady, S. R., Colangelo, C. M., Lindstrom, J. M., and Picciotto, M. R. (2013) Exploring the nicotinic acetylcholine receptor-associated proteome with iTRAQ and transgenic mice. Genomics Proteomics Bioinformatics 11, 207-218, (PMCID: PMC3806329).

164. Ko, J. H., Wang, Y. S., Nakamura, A., Guo, L. T., Soll, D., and Umehara, T. (2013) Pyrrolysyl-tRNA synthetase variants reveal ancestral aminoacylation function. FEBS Lett. 587, 3243-3248, (PMCID: PMC3778162).

163. Ivanov, A. R., Colangelo, C. M., Dufresne, C. P., Friedman, D. B., Lilley, K. S., Mechtler, K., Phinney, B. S., Rose, K. L., Rudnick, P. A., Searle, B. C., Shaffer, S. A., and Weintraub, S. T. (2013) Interlaboratory studies and initiatives developing standards for proteomics. Proteomics 13, 904-909, (PMCID: PMC3863631).

162. Colangelo, C. M., Chung, L., Bruce, C., and Cheung, K. H. (2013) Review of software tools for design and analysis of large scale MRM proteomic datasets. Methods 61, 287-298, (PMCID: PMC 3775261).

161. Bruce, C., Stone, K., Gulcicek, E., and Williams, K. (2013) Proteomics and the analysis of proteomic data: 2013 overview of current protein-profiling technologies. Curr. Protoc. Bioinformatics 41, 13.21.1-13.21.17 (PMCID: PMC 3688054).

160. Bansal, N., Zhang, M., Bhaskar, A., Itotia, P., Lee, E., Shlyakhtenko, L. S., Lam, T. T., Fritz, A., Berezney, R., Lyubchenko, Y. L., Stafford, W. F., and Thapar, R. (2013) Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1. Biochemistry 52, 520-536, (PMCID: PMC 3580866).

159. Antinone, S. E., Ghadge, G. D., Lam, T. T., Wang, L., Roos, R. P., and Green, W. N. (2013) Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants. J. Biol. Chem. 288, 21606-21617, (PMCID: PMC 3724620).

158. Zhang, Y. Q., Henderson, M. X., Colangelo, C. M., Ginsberg, S. D., Bruce, C., Wu, T., and Chandra, S. S. (2012) Identification of CSPalpha clients reveals a role in dynamin 1 regulation. Neuron 74, 136-150, (PMCID: PMC 3328141).

157. Zhang, M., Lam, T. T., Tonelli, M., Marzluff, W. F., and Thapar, R. (2012) Interaction of the histone mRNA hairpin with stem-loop binding protein (SLBP) and regulation of the SLBP-RNA complex by phosphorylation and proline isomerization. Biochemistry 51, 3215-3231, (PMCID: PMC 3328597).

156. Sherwin, R., Slayman, C., Rockwell, S., Williams, K., Carson, R., Mane, S., Seow, H., Max, J., and Johnson, T. (2012) Yale Center for Clinical Investigation: Leveraging Industry Partnerships and Research Cores. Clinical and Translational Science 5, 435-436,

155. Shen, H., Song, Y., Colangelo, C. M., Wu, T., Bruce, C., Scabia, G., Galan, A., Maffei, M., and Goldstein, D. R. (2012) Haptoglobin activates innate immunity to enhance acute transplant rejection in mice. J. Clin. Invest. 122, 383-387, (PMCID: PMC 3248290).

154. Sathyanesan, M., Girgenti, M. J., Banasr, M., Stone, K., Bruce, C., Guilchicek, E., Wilczak-Havill, K., Nairn, A., Williams, K., Sass, S., Duman, J. G., and Newton, S. S. (2012) A molecular characterization of the choroid plexus and stress-induced gene regulation. Transl. Psychiatry 2, e139, (PMCID: PMC 3410626).

153. Marin, E. P., Derakhshan, B., Lam, T. T., Davalos, A., and Sessa, W. C. (2012) Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases. Circ. Res. 110, 1336-1344, (PMCID: PMC 3428238).

152. Krishnan, N., Lam, T. T., Fritz, A., Rempinski, D., O'Loughlin, K., Minderman, H., Berezney, R., Marzluff, W. F., and Thapar, R. (2012) The prolyl isomerase Pin1 targets stem-loop binding protein (SLBP) to dissociate the SLBP-histone mRNA complex linking histone mRNA decay with SLBP ubiquitination. Mol. Cell. Biol. 32, 4306-4322, (PMCID: PMC 3486140).

151. Ye, Z. J., Gulcicek, E., Stone, K., Lam, T., Schulz, V., and Weissman, S. M. (2011) Complex interactions in EML cell stimulation by stem cell factor and IL-3. Proc. Natl. Acad. Sci. U. S. A. 108, 4882-4887, (PMCID: PMC 3064389).

150. Shabman, RS.; D W. Leung, J Johnson, N Glennon, EE Gulcicek, KL Stone; L Leung, L Hensley, G K. Amarasinghe, Christopher F. Basler (2011) DRBP76 associates with ebolavirus VP35 and suppresses viral polymerase function. J. Infect. Dis. 204, S911-S918; (PMID: 2198776).

149. Shabman, R. S., Gulcicek, E. E., Stone, K. L., and Basler, C. F. (2011) The Ebola virus VP24 protein prevents hnRNP C1/C2 binding to karyopherin alpha1 and partially alters its nuclear import. J. Infect. Dis. 204 Suppl. 3, S904-910, (PMCID: PMC 3189985).

148. Rinehart, J., Vazquez, N., Kahle, K. T., Hodson, C. A., Ring, A. M., Gulcicek, E. E., Louvi, A., Bobadilla, N. A., Gamba, G., and Lifton, R. P. (2011) WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. J. Biol. Chem. 286, 30171-30180, (PMCID: PMC 3191056).

147. Pirruccello, M., Swan, L. E., Folta-Stogniew, E., and De Camilli, P. (2011) Recognition of the F&H motif by the Lowe syndrome protein OCRL. Nat. Struct. Mol. Biol. 18, 789-795, (PMCID: PMC 3130824).

146. Noga, E. J., Stone, K. L., Wood, A., Gordon, W. L., and Robinette, D. (2011) Primary structure and cellular localization of callinectin, an antimicrobial peptide from the blue crab. Dev Comp. Immunol. 35, 409-415, (PMCID: PMC 3046215).

145. Kiraly, D. D., Stone, K. L., Colangelo, C. M., Abbott, T., Wang, Y., Mains, R. E., and Eipper, B. A. (2011) Identification of kalirin-7 as a potential post-synaptic density signaling hub. J Proteome Res. 10, 2828-2841, (PMCID: PMC 3107868).

144. Bordner, K. A., George, E. D., Carlyle, B. C., Duque, A., Kitchen, R. R., Lam, T. T., Colangelo, C. M., Stone, K. L., Abbott, T. B., Mane, S. M., Nairn, A. C., and Simen, A. A. (2011) Functional genomic and proteomic analysis reveals disruption of myelin-related genes and translation in a mouse model of early life neglect. Front. Psychiatry 2, 18, (PMCID: PMC 3098717).

143. Bianchetta, M. J., Lam, T. T., Jones, S. N., and Morabito, M. A. (2011) Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons. J. Neurosci. 31, 12029-12035, (PMCID: PMC 3190401).

142. Seo, J. K., Stephenson, J., Crawford, M., Stone, K. L., and Noga, E. J. (2010) American oyster, Crassostrea virginica, expresses a potent antibacterial histone H2B protein. Mar Biotechnol. (NY) 12, 543-551.

141. Rajagopal, C., Stone, K. L., Mains, R. E., and Eipper, B. A. (2010) Secretion stimulates intramembrane proteolysis of a secretory granule membrane enzyme. J. Biol. Chem. 285, 34632-34642, (PMCID: PMC 2966079).

140. Du, J., Roberts, D., Lin, K., Belcourt, M., King, I., and Lam, T.K. (2010) Case Study: Identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine, in Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification (Nassar, A. ed) Chapter 6.

139. Nassar, A.F., Du, J., Roberts, D., Lin, K., Belcourt, M., King, I., and Lam, T.K. (2010) Case Study: The unanticipated loss of N2 from novel DNA alkylating agent laromustine by collision-induced dissociation: Novel Rearrangements, in Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification (Nassar, A. ed.), Chapter 5.

138. Fogel, A. I., Li, Y., Giza, J., Wang, Q., Lam, T. T., Modis, Y., and Biederer, T. (2010) N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion. J. Biol. Chem. 285, 34864-34874, (PMCID: PMC 2966101).

137. Ercan-Sencicek, A. G., Stillman, A. A., Ghosh, A. K., Bilguvar, K., O'Roak, B. J., Mason, C. E., Abbott, T., Gupta, A., King, R. A., Pauls, D. L., Tischfield, J. A., Heiman, G. A., Singer, H. S., Gilbert, D. L., Hoekstra, P. J., Morgan, T. M., Loring, E., Yasuno, K., Fernandez, T., Sanders, S., Louvi, A., Cho, J. H., Mane, S., Colangelo, C. M., Biederer, T., Lifton, R. P., Gunel, M., and State, M. W. (2010) L-histidine decarboxylase and Tourette's syndrome. N. Engl. J. Med. 362, 1901-1908, (PMCID: PMC 2894694).

136. Davalos, A., Fernandez-Hernando, C., Sowa, G., Derakhshan, B., Lin, M. I., Lee, J. Y., Zhao, H., Luo, R., Colangelo, C., and Sessa, W. C. (2010) Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Mol. Cell. Proteomics 9, 2109-2124, (PMCID: PMC 2953909).

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