MS & Proteomics Resource
Resource Description
The Mass Spectrometry (MS) & Proteomics Resource of the W.M. Keck Foundation Biotechnology Resource Laboratory provides efficient and cost effective proteomics and small molecule mass spectrometry based services. Beside from our developed Standard Operating Procedure (SOP) offered for many of our MS services, we also strive to continue to bring state-of-the-art mass spectrometry based biotechnologies through input and request from our users. These technologies are developed and implemented with a broad spectrum of mass spectrometry based techniques and protein/peptide/small molecule chemistries to separate, characterize, profile, and quantify analytes from complex biological samples.
Our services include:
- Basic Protein ID from gel bands
- Protein ID from complex solution
- Protein Posttranslational Modification (PTM) identification
- Protein profiling and quantitation (Labeled Free Quantitation, iTRAQ, TMT, & SILAC)
- Intact Protein Determination.
- High Resolution (HR) MS for small molecule and structural elucidation
- Targeted Proteomics (PRM)
DISCLAIMER
Due to their high complexity and variability, we cannot guarantee that our SOP for sample preparation will be applicable to all proteomics samples that we receive. ALL CLAIMS, REGARDLESS OF THEIR NATURE, MUST BE BROUGHT TO OUR ATTENTION WITHIN 30 DAYS OF RESULTS DISSEMINATION. Though we will do our very best to ensure (by looking through literature and other sources) that the highest quality services are provide for every sample that are submitted to us.
THE MS & PROTEOMICS RESOURCE SHALL NOT BE LIABLE FOR INCIDENTAL, CONSEQUENTIAL, OR UNANTICIPATED OUTCOME RESULTING FROM SAMPLE PREPARATION INCOMPATIBILITY TO OUR SOP, NOR SHALL ITS LIABILITY IN ANY CASE EXCEED THE ESTIMATED COST OF THE SERVICES RENDERED.
Please acknowledge our funders in your publication!
If any part of the mass spectrometry data/analyses provided by us are to be included in a manuscript, please utilize the below statement and include it in the acknowledgement section of your manuscript submission. Thank you.
“We also thank the MS & Proteomics Resource at Yale University for providing the necessary mass spectrometers and the accompany biotechnology tools funded in part by the Yale School of Medicine and by the Office of The Director, National Institutes of Health (S10OD02365101A1, S10OD019967, and S10OD018034). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.”