Proteomics Centers closely Associated with the Keck MS & Proteomics Resource

Yale/NIDA Neuroproteomics Research Center

Theme: "Proteomics of Altered Signaling in Addiction”.
proteomics combined with signal transduction in the brain to identify adaptive
changes in protein signaling that occur in response to substance abuse.
Budget period 8/23/2004 – 5/31/2014

Yale/NHLBI Proteomics Center

1 of 10 national centers established in 2002
Protein profiling & MS components located in the Keck MS Lab
Supports research on vascular biology, hematopoiesis, blood pressure
Budget Period 10/2002 - 9/2009 NCE

Northeast Biodefense Center (NBC)

1 of 8 Regional Centers of Excellence established in 2003
200 faculty at the CDC and 36 institutions in NY, CT, and NJ.
Basic science and clinical biodefense research programs
First responders in the event of a biodefense emergency
Budget period 9/3/03-2/29/10

Center for High Performance Computation (HPC) in Biomedicine at Yale University

equipped with a Beowulf cluster
funded by a $1.6 million dollar NIH High End Instrumentation
Uses include large scale MS/MS analysis (MudPIT, iTRAQ, PTM’s)
X!!tandem which is a parallelized version of X!tandem

Proteomics Shared Resource of the Yale Comprehensive Cancer Center

supports the Yale Comprehensive Cancer Center (YCC) Proteomics Resource
providing protein profiling analysis (i.e. DIGE, iTRAQ, SILAc etc.),
mass spectrometric and biophysical analysis for YCC members.
Budget period 08/09/07-7/31/12