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Fluorescence in situ and in vivo microscopy

The Department has available multiple fluorescence and confocal microscopes suitable for the detection of up to 6 channels ideal for in situ microscopy of cells and tissues that are shared by individual laboratories. The department has access to an Olympus BX61WI fluorescence microscope equipped with a 20×, 0.95NA water immersion Olympus objective, single-beam LaVision TriM laser-scanning microscope (LaVision Biotec) run with Inspector software, and illuminated with a Chameleon Vision II Ti:Sapphire laser (Coherent) suitable for intravital 2-photon microscopy. The intravital imaging facility is run by David Gonzalez and directed by Dr. Ann Haberman, in the Departemnt of Laboratory Medicine.


Several excellent core facilities in other departments at Yale are available including peptide synthesis, oligonucleotide synthesis, protein sequencing, and DNA sequencing.

Cell Imaging

An example of Cell Imaging gathered utilizing the onsite facilities.