2025
Sex differences in proteomics of cardiovascular disease – Results from the Yale-CMD registry
Liu Y, Wang Z, Collins S, Testani J, Safdar B. Sex differences in proteomics of cardiovascular disease – Results from the Yale-CMD registry. IJC Heart & Vasculature 2025, 58: 101667. PMID: 40224648, PMCID: PMC11987697, DOI: 10.1016/j.ijcha.2025.101667.Peer-Reviewed Original ResearchCMD patientsUpregulation of immune pathwaysCardiovascular diseaseProximity extension assayBody mass indexRegulation of blood flowSex differencesProteomic profilingIschemic symptomsCAD patientsMass indexIncreased angiogenesisGlucose metabolic pathwaysDifferential protein expressionPatientsSex-specific pathwaysProtein expressionImmune pathwaysBlood flowBlood samplesPrecision medicineINSL3Metabolic pathwaysPathway analysisExtension assay
2024
Sex differences in proteomics of cardiovascular disease: results from the Yale-CMD registry
Liu Y, Wang Z, Collins S, Testani J, Kleinstein S, Safdar B. Sex differences in proteomics of cardiovascular disease: results from the Yale-CMD registry. European Heart Journal 2024, 45: ehae666.3091. DOI: 10.1093/eurheartj/ehae666.3091.Peer-Reviewed Original ResearchCoronary microvascular dysfunctionCoronary artery diseaseUpregulation of lipidCardiovascular diseaseAcute heart failureCoronary artery disease cohortHistory of diabetesPathophysiology of CVDProximity extension assayBody mass indexSignificant sex differencesRegulation of blood flowSerum proteomic profilesSex differencesProteomic profilingAngiogenesis-related proteinsCardiac PET/CTHemodynamic instabilityIschemic symptomsMicrovascular dysfunctionFalse discovery rateHeart failureFebrile illnessFunctional pathway analysisMass index
2022
Angiographic Lesion Discordance in Women Presenting With Ischemic Heart Disease: Comparison of Visual Assessment, Quantitative Coronary Angiography, and Quantitative Flow Ratio.
Gitto M, Saito Y, Taoutel R, Schneider MD, Papoutsidakis N, Ardito S, Henry G, Cristea E, Lansky AJ, Altin SE. Angiographic Lesion Discordance in Women Presenting With Ischemic Heart Disease: Comparison of Visual Assessment, Quantitative Coronary Angiography, and Quantitative Flow Ratio. Journal Of Invasive Cardiology 2022, 34: e202-e209. PMID: 35089162, DOI: 10.25270/jic/21.00146.Peer-Reviewed Original ResearchConceptsQuantitative coronary angiographyIschemic heart diseaseQuantitative flow ratioStress perfusion imagingDiameter stenosisCoronary angiographyIschemic symptomsCoronary revascularizationHeart diseasePerfusion imagingStenosis severityIndependent core laboratoryCohort of womenVisual assessmentCoronary stenosis severityConsecutive patientsAngiographic severityCoronary stenosisLesion assessmentClinical practiceCore laboratoryLesionsAngiographyWomenBlinded operators
2019
Surgical Treatment of Chronic Hand Ischemia: A Systematic Review and Case Series
Colen DL, Ben-Amotz O, Stephanie T, Serebrakian A, Carney MJ, Gerety PA, Levin LS. Surgical Treatment of Chronic Hand Ischemia: A Systematic Review and Case Series. The Journal Of Hand Surgery (Asian-Pacific Volume) 2019, 24: 359-370. PMID: 31438795, DOI: 10.1142/s2424835519500462.Peer-Reviewed Original ResearchConceptsChronic hand ischemiaHand ischemiaNew ulcerationSurgical interventionSurgical treatmentSystematic reviewLast-line treatmentRest painArtery bypassIschemic symptomsMedical optimizationConservative treatmentPharmacologic therapyPrimary outcomeSecondary amputationVenous arterializationCase seriesLine treatmentCold intoleranceMore complicationsArterial bypassConservative measuresSurgical techniqueIschemiaPRISMA guidelines
2007
Ischaemic symptoms, quality of care and mortality during myocardial infarction
Schelbert EB, Rumsfeld JS, Krumholz HM, Canto JG, Magid DJ, Masoudi FA, Reid KJ, Spertus JA. Ischaemic symptoms, quality of care and mortality during myocardial infarction. Heart 2007, 94: e2. PMID: 17639097, PMCID: PMC3703470, DOI: 10.1136/hrt.2006.111674.Peer-Reviewed Original ResearchConceptsIschemic symptomsMyocardial infarctionQuality of careST-elevation myocardial infarctionACE/ARBNon-cardiac comorbiditiesPositive cardiac enzymesEvidence of infarctionHospital mortalityCessation counsellingHospital survivalReperfusion therapyCardiac enzymesConsecutive patientsMI careMI symptomsCare indicatorsPatient reportsSymptom recognitionChart documentationPatientsUS hospitalsSymptomsInfarctionCare
2006
Presence of prostacyclin receptor in arteriosclerotic human femoral artery.
Muto A, Kondo Y, Yamamoto Y, Yamada H, Washimi O, Miyauchi Y, Kudo F, Dardik A, Nishibe T. Presence of prostacyclin receptor in arteriosclerotic human femoral artery. International Angiology 2006, 25: 175-8. PMID: 16763535.Peer-Reviewed Case Reports and Technical NotesConceptsFemoral arteryVascular endothelial cellsEndothelial cellsArteriosclerosis obliteransHuman femoral arteriesProstacyclin analogueIP receptorProstacyclin receptorLuminal sideVon Willebrand factorIschemic symptomsVascular eventsRelaxant effectLower extremitiesCardiovascular homeostasisLimb amputationAtherosclerotic lesionsPositive cellsArterySingle immunohistochemistryWillebrand factorReceptorsStrong expressionObliteransPatients
2001
Continuous Monitoring of Jugular Bulb Oxygenation during Carotid Temporary Balloon Occlusion
Schwamm L, Bellon R, Norbash A, Budzik R, Ogilvy C, Putman C. Continuous Monitoring of Jugular Bulb Oxygenation during Carotid Temporary Balloon Occlusion. Stroke 2001, 32: 342-342. DOI: 10.1161/str.32.suppl_1.342-b.Peer-Reviewed Original ResearchTemporary balloon occlusionSjvO 2Hemispheric hypoperfusionBalloon occlusionHead/neck cancerJugular bulb oximetryJugular bulb oxygenationCerebral oxygen extractionLow-flow ischemiaPoor predictive valueTreatment of aneurysmsContinuous neurologic monitoringAbnormal SPECTICA sacrificeBaseline BPIschemic symptomsNeurologic symptomsConsecutive patientsHemodynamic managementNeurologic monitoringEquivocal symptomsJugular bulbPermanent occlusionSystemic heparinizationNeck cancer
1997
Pharmacological elevation of blood pressure in acute stroke. Clinical effects and safety.
Rordorf G, Cramer S, Efird J, Schwamm L, Buonanno F, Koroshetz W. Pharmacological elevation of blood pressure in acute stroke. Clinical effects and safety. Stroke 1997, 28: 2133-8. PMID: 9368553, DOI: 10.1161/01.str.28.11.2133.Peer-Reviewed Original ResearchConceptsBlood pressure thresholdAcute strokeBlood pressureInduced hypertensionCerebral arterySystolic blood pressure thresholdNeurological intensive care unitPhenylephrine-Induced HypertensionAcute cerebral ischemiaSubset of patientsIntensive care unitPressure thresholdCardiac morbidityIschemic deficitsIschemic symptomsPressor agentsBaseline characteristicsIschemic strokeNeurological deficitsCerebral ischemiaCerebral perfusionBrain edemaCare unitClinical effectsIntracerebral hemorrhage
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply