2025
Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression
Harada A, Yasumizu Y, Harada T, Fumoto K, Sato A, Maehara N, Sada R, Matsumoto S, Nishina T, Takeda K, Morii E, Kayama H, Kikuchi A. Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression. Nature Communications 2025, 16: 3653. PMID: 40246836, PMCID: PMC12006413, DOI: 10.1038/s41467-025-58748-9.Peer-Reviewed Original ResearchConceptsColon cancer progressionSingle-cell RNA-seq dataCancer progressionEndothelial cellsRNA-seq dataColon cancer aggressivenessSuppression of angiogenesisColon cancer growthColon cancer formationCancer aggressivenessInflammatory fibroblastsVEGF receptor1Cancer growthPromote tumorigenesisCancer formationWnt5aMeta-analysisWnt ligandsLuminal sideFibroblast subtypesColonHypoxic environmentFibroblastsCells
2016
The fetal-maternal interface of the nine-banded armadillo: endothelial cells of maternal sinus are partially replaced by trophoblast
Chavan AR, Wagner GP. The fetal-maternal interface of the nine-banded armadillo: endothelial cells of maternal sinus are partially replaced by trophoblast. Zoological Letters 2016, 2: 11. PMID: 27284459, PMCID: PMC4899922, DOI: 10.1186/s40851-016-0048-1.Peer-Reviewed Original ResearchMaternal immune systemImmune systemFetal-maternal immune toleranceSemi-allogenic fetusFetal-maternal interfaceVascular endothelial layerUterine connective tissuePresence of leukocytesEndometrial stromaImmune toleranceImmunohistochemical toolsIntervillous spaceUterine tissuePlacental fibrinoidTrophoblast cellsInvasive placentationEndothelial liningMaternal sinusesEndothelial cellsEndothelial layerSinusConnective tissueBlood sinusesMaternal tissuesLuminal side
2015
Mucosal signaling in the bladder
Chai TC, Russo A, Yu S, Lu M. Mucosal signaling in the bladder. Autonomic Neuroscience 2015, 200: 49-56. PMID: 26422993, DOI: 10.1016/j.autneu.2015.08.009.Peer-Reviewed Original ResearchConceptsElectrical field stimulationLamina propriaNerve fibersMuscularis mucosaeNeural activitySpontaneous electrical activityNon-neuronal cellsSmooth muscle fibersMucosal contractionEfferent nervesBladder disordersAutonomic nervesAfferent activityBladder mucosaField stimulationHigh prevalenceMucosaStretch stimulusUrothelial cellsNerveElectrical activityMuscle fibersLuminal sideUrotheliumMultilayered urothelium
2006
Presence of prostacyclin receptor in arteriosclerotic human femoral artery.
Muto A, Kondo Y, Yamamoto Y, Yamada H, Washimi O, Miyauchi Y, Kudo F, Dardik A, Nishibe T. Presence of prostacyclin receptor in arteriosclerotic human femoral artery. International Angiology 2006, 25: 175-8. PMID: 16763535.Peer-Reviewed Case Reports and Technical NotesConceptsFemoral arteryVascular endothelial cellsEndothelial cellsArteriosclerosis obliteransHuman femoral arteriesProstacyclin analogueIP receptorProstacyclin receptorLuminal sideVon Willebrand factorIschemic symptomsVascular eventsRelaxant effectLower extremitiesCardiovascular homeostasisLimb amputationAtherosclerotic lesionsPositive cellsArterySingle immunohistochemistryWillebrand factorReceptorsStrong expressionObliteransPatients
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