2023
Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix
Hoffman M, Clifton R, Biggio J, Saade G, Ugwu L, Longo M, Bousleiman S, Clark K, Grobman W, Frey H, Chauhan S, Dugoff L, Manuck T, Chien E, Rouse D, Simhan H, Esplin M, Macones G, Bickus M, Facco F, Tita A, Grant J, Casey B, Harris S, Harper L, Dunn D, Longo S, Hendricks M, Lata-Arias K, Costantine M, Bartholomew A, Cline D, Harper S, Ward C, Gardner N, Brindle S, Weigand S, McKenna D, Snow E, Fennig K, Habli M, Lambers D, McClellan M, Metz T, Sowles A, Varner M, Hill K, Morby V, Meadows C, Allard D, Werner E, Rousseau J, Milano J, Pettker C, Leventhal J, Gyamfi-Bannerman C, Wapner R, Carmona V, Firman B, Vanneman A, Palomares K, Beche I, Skupski D, Chan-Akeley R, Salazar A, Pacheco L, McCoy L, Saad A, Jain S, Omere C, Clifford C, McDonnold M, Chien E, Dalton W, Polito L, Milluzi C, Kushner K, Maile A, Bell J, Hackney D, Ortiz F, Timlin S, Goodnight W, Manuck T, Beamon C, Nun H, Eichelberger K, Moore A, Hughes B, Ferrara J, Grobman W, Mallett G, Stein L, Miller E, Plunkett B, Kearns K, Palatnik A, Malone T, Parry S, Pizzi C, Craig J, Filipczak A, Thom E, Doherty L, Hubbard A, Erikson P, Pinto T, Marcharchand P, Reddy U, Miodovnik M, Archer S. Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix. JAMA 2023, 330: 340-348. PMID: 37490086, PMCID: PMC10369212, DOI: 10.1001/jama.2023.10812.Peer-Reviewed Original ResearchConceptsCervical pessaryUsual carePreterm birthShort cervixVaginal progesteroneCervical lengthSingleton pregnanciesFetal deathPrimary outcomeInfant deathPrior spontaneous preterm birthTransvaginal ultrasound cervical lengthCervical pessary placementWeeks 0 daysSpontaneous preterm birthUltrasound cervical lengthWeeks 6 daysThird interim analysisNeonatal/infant mortalityPreterm deliverySingleton gestationsBaseline characteristicsUltrasound evidencePessary placementTransvaginal ultrasound
2021
Half Century Since SIDS: A Reappraisal of Terminology
Shapiro-Mendoza C, Palusci V, Hoffman B, Batra E, Yester M, Corey T, Sens M, Moon R, Goodstein M, Abu Jawdeh E, Carlin R, Colvin J, Hwang S, Hauck F, Haney S, Sirotnak A, Asnes A, Gavril A, Greenlee Girardet R, Hoffert Gilmartin A, Heavilin N, Laskey A, Messner S, Mohr B, Nienow S, Rosado N, Agran P, Hirsh M, Johnston B, Kendi S, Lee L, Monroe K, Schaechter J, Tenenbein M, Zonfrillo M, Quinlan K, Bechtel K, Berkowitz C, Needelman H. Half Century Since SIDS: A Reappraisal of Terminology. 2021, 148: e2021053746. PMID: 34544849, PMCID: PMC8487943, DOI: 10.1542/peds.2021-053746.Peer-Reviewed Original ResearchConceptsNonphysician cliniciansInfant deathSudden infant deathMental health careClinician disciplineAppropriate referralPediatric specialtiesChild deathsPediatriciansDiagnostic shiftEffective interventionsPhysiciansCliniciansDeathHealth careCaregiversTragic newsConsistent terminologyOpen communicationPathophysiologyDeath terminologyInfantsReferralEtiologyMortalityRespiratory Syncytial Virus–Associated Mortality Among Young Infants in Karachi, Pakistan: A Prospective Postmortem Surveillance Study
Kazi AM, Aguolu OG, Mughis W, Ahsan N, Jamal S, Khan A, Qureshi HM, Yildirim I, Malik FA, Omer SB. Respiratory Syncytial Virus–Associated Mortality Among Young Infants in Karachi, Pakistan: A Prospective Postmortem Surveillance Study. Clinical Infectious Diseases 2021, 73: s203-s209. PMID: 34472574, PMCID: PMC8411247, DOI: 10.1093/cid/ciab488.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusRespiratory symptomsInfant deathRSV seasonalityRole of RSVYoung infantsPresence of RSVMultivariable logistic regression analysisMaternal immunization strategiesSignificant mortality burdenVaccine-hesitant populationYoung infant deathsMultivariable logistic regressionCold-like symptomsSignificant predictorsLogistic regression analysisPostneonatal ageRSV mortalityRSV seasonMaternal immunizationInfant morbidityNasopharyngeal specimensNasopharyngeal swabsSyncytial virusRespiratory illnessSeizure‐related deaths in children: The expanding spectrum
Harowitz J, Crandall L, McGuone D, Devinsky O. Seizure‐related deaths in children: The expanding spectrum. Epilepsia 2021, 62: 570-582. PMID: 33586153, PMCID: PMC7986159, DOI: 10.1111/epi.16833.Peer-Reviewed Original ResearchConceptsSeizure-related deathSudden unexpected infant deathSudden unexplained deathUnexpected infant deathEpileptic factorsMale predominanceNonfebrile seizuresHippocampal abnormalitiesFetal lossProne positionUnexplained deathUnexpected deathFamily historyNeuronal excitabilityInfant deathUnwitnessed deathsEpidemiological studiesEpilepsy shareEpilepsy diagnosisDeathGenetic featuresSeizuresChildrenPotential causesFebrile
2020
Impact of statewide safe sleep legislation on hospital practices and rates of sudden unexpected infant deaths
Bechtel K, Gawel M, Vincent GA, Violano P. Impact of statewide safe sleep legislation on hospital practices and rates of sudden unexpected infant deaths. Injury Epidemiology 2020, 7: 22. PMID: 32532344, PMCID: PMC7291413, DOI: 10.1186/s40621-020-00247-0.Peer-Reviewed Original ResearchNewborn hospital dischargeUnsafe sleep environmentsUnexpected infant deathAnticipatory guidanceSleep environmentHospital dischargeSafe sleepBirthing hospitalsInfant deathExact testPositional asphyxiaSudden unexpected infant deathHospitals/centersProportion of deathsCause of deathPost-neonatal periodFisher's exact testNewborn caregiversPediatric guidelinesMore infantsBirthing centerSUID casesHospital practiceHospitalAmerican Academy
2019
Characteristics That Distinguish Abusive From Nonabusive Causes of Sudden Unexpected Infant Deaths
Bechtel K, Derbyshire M, Gaither JR, Leventhal JM. Characteristics That Distinguish Abusive From Nonabusive Causes of Sudden Unexpected Infant Deaths. Pediatric Emergency Care 2019, 37: e780-e783. PMID: 30829845, DOI: 10.1097/pec.0000000000001787.Peer-Reviewed Original ResearchConceptsSudden unexpected infant deathUnexpected infant deathChild protective services involvementTime of deathSentinel injuryManner of deathSpontaneous circulationInfant deathEmergency medical services transportEmergency department settingMaternal substance useCase-control designService involvementMedical examiner recordsClinical outcomesEmergency departmentDepartment settingCardiopulmonary resuscitationFatal child abuseServices transportSubstance useDeathFurther studiesSignificant differencesInfants
2018
Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality
Luke B, Brown MB, Wantman E, Seifer DB, Sparks AT, Lin PC, Doody KJ, Van Voorhis BJ, Spector LG. Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality. Journal Of Assisted Reproduction And Genetics 2018, 36: 121-138. PMID: 30328574, PMCID: PMC6338589, DOI: 10.1007/s10815-018-1333-z.Peer-Reviewed Original ResearchConceptsMaternal fertility statusRisk of prematurityIVF groupIVF pregnanciesDonor oocytesPlacental complicationsGreater riskInfant deathThawed embryosResultsThe study populationConfidence intervalsFertilization pregnanciesIVF infantsNICU admissionGestational diabetesInfant morbidityOdds ratioInfertility treatmentDeath certificatesLive birthsStudy populationPregnancyInfant's birthPrematurityOocyte sourceUS Hispanics and Preterm Births
Bermúdez-Millán A, Pérez-Escamilla R. US Hispanics and Preterm Births. Nutrition And Health 2018, 231-245. DOI: 10.1007/978-3-319-90988-2_13.Peer-Reviewed Original ResearchVitamin D deficiencyRisk factorsPreterm birthD deficiencyPreterm deliveryPremature birthHispanic womenMaternal socio-demographic characteristicsNutrition-related risk factorsNon-Hispanic white womenLong-term morbidityPregnancy-related conditionsMaternal lifestyleSocio-demographic characteristicsInfant deathWhite womenUS HispanicsBirthWomenPotential interactionsDeficiencyFurther researchDeliveryFactorsMorbidityPrenatal maternal stress, fetal programming, and mechanisms underlying later psychopathology—A global perspective
Glover V, O'Donnell KJ, O'Connor TG, Fisher J. Prenatal maternal stress, fetal programming, and mechanisms underlying later psychopathology—A global perspective. Development And Psychopathology 2018, 30: 843-854. PMID: 30068411, DOI: 10.1017/s095457941800038x.BooksMeSH KeywordsAnxiety DisordersBrainChildCross-Cultural ComparisonDepressive DisorderDeveloping CountriesFemaleFetal DevelopmentHumansHypothalamo-Hypophyseal SystemInfantMental DisordersPituitary-Adrenal SystemPregnancyPrenatal Exposure Delayed EffectsPsychopathologyPsychosocial DeprivationRisk FactorsSocial EnvironmentStress, PsychologicalConceptsPrenatal stressLater psychopathologyPregnancy-specific anxietyPrenatal maternal stressPrenatal stress altersAdrenal axisChild neurodevelopmentHigh-income countriesFetal programmingInfant deathMaternal stressGene-environment interactionsNutritional deficienciesMothers' stressDifferent ethnic groupsStress altersPsychopathologyBiological differencesEthnic groupsInterpersonal violenceAnxietyCaucasian samplesHigh levelsPregnancyCytokines
2017
Bacteria disarm host-defence proteins
MacMicking JD. Bacteria disarm host-defence proteins. Nature 2017, 551: 303-304. PMID: 29072295, DOI: 10.1038/nature24157.Peer-Reviewed Original Research
2016
Impact of Optimized Breastfeeding on the Costs of Necrotizing Enterocolitis in Extremely Low Birthweight Infants
Colaizy T, Bartick M, Jegier B, Green B, Reinhold A, Schaefer A, Bogen D, Schwarz E, Stuebe A, Jobe A, Oh W, Vohr B, Walden R, Alksninis B, Hensman A, Leonard M, Noel L, Leach T, Watson V, Fanaroff A, Walsh M, Wilson-Costello D, Newman N, Siner B, Friedman H, Donovan E, Schibler K, Steichen J, Alexander B, Grisby C, Mersmann M, Mincey H, Hessling J, Gratton T, Stoll B, Adams-Chapman I, Hale E, LaRossa M, Carter S, Higgins R, Wright L, McClure E, Poindexter B, Lemons J, Dusick A, Kardatzke D, Lytle C, Appel D, Bohnke L, Eaken G, Herron D, Miller L, Richard L, Wilson L, Das A, Poole W, Wrage L, Hastings B, McClure E, Auman J, Taylor S, Stevenson D, Hintz S, Ball M, Kohn J, Baran J, Lee-Ancajas J, St. John N, Carlo W, Ambalavanan N, Nelson K, Peralta-Carcelen M, Bailey K, Biasini F, Chopko S, Collins M, Cosby S, Phillips V, Rector R, Finer N, Vaucher Y, Anderson J, Rasmussen M, Arnell K, Demetrio C, Fuller M, Henderson C, Posin D, Bell E, Colaizy T, Bauer C, Duara S, Worth A, Everett-Thomas R, Diaz A, Mathews E, Hamlin-Smith K, Jean-Gilles L, Calejo M, Frade S, Hiriart-Fajardo S, Gideon Y, Korones S, Bada H, Hudson T, Yolton K, Williams M, Laptook R, Salhab W, Broyles R, Madison S, Hickman J, Guzman A, Adams S, Madden L, Heyne E, Dooley C, Shankaran S, Delaney-Black V, Johnson Y, Bara R, Muran G, Kennedy D, Goldston L, Ehrenkranz R, Gettner P, Konstantino M, Romano E, Close N, Gilliam W, Poulsen J. Impact of Optimized Breastfeeding on the Costs of Necrotizing Enterocolitis in Extremely Low Birthweight Infants. The Journal Of Pediatrics 2016, 175: 100-105.e2. PMID: 27131403, PMCID: PMC5274635, DOI: 10.1016/j.jpeds.2016.03.040.Peer-Reviewed Original ResearchConceptsRisk of NECELBW infantsPreterm formulaHuman milkLow birth weight infantsExclusive preterm formulaIndirect nonmedical costsBirth weight infantsLow birthweight infantsSuboptimal feeding practicesDirect medical costsMaternal milk intakeSuboptimal feedingGlutamine TrialNEC incidenceWeight infantsNecrotizing enterocolitisNEC casesBirthweight infantsInfant deathMilk intakeNonmedical costsAdjusted modelMedical costsTheoretical cohort
2014
National Association of Medical Examiners Position Paper: Recommendations for the Postmortem Assessment of Suspected Head Trauma in Infants and Young Children
Gill J, Andrew T, Gilliland M, Love J, Matshes E, Reichard R. National Association of Medical Examiners Position Paper: Recommendations for the Postmortem Assessment of Suspected Head Trauma in Infants and Young Children. Academic Forensic Pathology 2014, 4: 206-213. DOI: 10.23907/2014.032.Peer-Reviewed Original ResearchInflicted head traumaHead traumaPostmortem examinationInfant deathAncillary laboratory testsMedical Examiners Position PaperManner of deathAncillary studiesPostmortem assessmentTraumaDeathForensic pathologistsMedical examinersYoung childrenInfantsCorrect certificationExaminationPosition paperLaboratory testsAssociationNational AssociationAvailable dataRecommendations
2012
Sudden Unexpected Infant Death
Bechtel K. Sudden Unexpected Infant Death. Pediatric Emergency Care 2012, 28: 1085-1089. PMID: 23034500, DOI: 10.1097/pec.0b013e31826d1e9a.Peer-Reviewed Original ResearchConceptsSudden unexpected infant deathSudden infant death syndromeInfant death syndromeUnexpected infant deathEmergency departmentInfant deathDeath syndromeInterviews of caregiversChild death review teamsLocal medical examinersObvious causeED practitionersFatal child abuseED guidelinesCompassionate mannerMedical examinersDeathSyndromeReview teamCauseChild abuseInfants
2011
Impact of an Educational Intervention on Caregivers’ Beliefs About Infant Crying and Knowledge of Shaken Baby Syndrome
Bechtel K, Le K, Martin KD, Shah N, Leventhal JM, Colson E. Impact of an Educational Intervention on Caregivers’ Beliefs About Infant Crying and Knowledge of Shaken Baby Syndrome. Academic Pediatrics 2011, 11: 481-486. PMID: 21940233, DOI: 10.1016/j.acap.2011.08.001.Peer-Reviewed Original ResearchConceptsShaken baby syndromeHospital dischargeIntervention groupEducational interventionAnticipatory guidanceUrban primary care centerPediatric residentsInfant cryingNewborn hospital dischargeHistorical control groupPrimary care centersIntervention group caregiversBeliefs/knowledgePostpartum interventionsCare centerAdjusted associationsInfant deathBaby syndromeShaken BabyHospital staffControl groupYoung infantsMore mothersInfantsLogistic regression
2003
Comparison of Two Strategies for Administering Nevirapine to Prevent Perinatal HIV Transmission in High-Prevalence, Resource-Poor Settings
Stringer JS, Sinkala M, Stout JP, Goldenberg RL, Acosta EP, Chapman V, Kumwenda-Phiri R, Vermund SH. Comparison of Two Strategies for Administering Nevirapine to Prevent Perinatal HIV Transmission in High-Prevalence, Resource-Poor Settings. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2003, 32: 506-513. PMID: 12679702, PMCID: PMC2745994, DOI: 10.1097/00126334-200304150-00007.Peer-Reviewed Original ResearchConceptsHigh-prevalence settingsClinic AClinic BVCT servicesPrevent Perinatal HIV TransmissionPerinatal HIV acquisitionPerinatal HIV preventionPerinatal HIV transmissionKnowledge of serostatusResource-poor settingsNevirapine therapyNVP therapyHIV acquisitionHIV testingHIV statusHIV transmissionPregnant womenCord bloodHIV preventionHigh prevalenceInfant deathUniversal therapyClinicTherapyMaternal reports
2001
Injury related infant death: the impact of race and birth weight
Jain A, Khoshnood B, Lee K, Concato J. Injury related infant death: the impact of race and birth weight. Injury Prevention 2001, 7: 135. PMID: 11428561, PMCID: PMC1730711, DOI: 10.1136/ip.7.2.135.Peer-Reviewed Original ResearchConceptsLow birthweight babiesBirth weightUnintentional injuriesRisk factorsOdds ratioSociodemographic factorsBirthweight babiesRisk of homicideInfant deathHigh riskImportant independent risk factorEffect of raceAfrican AmericansIndependent risk factorPreventable risk factorsAdjusted odds ratioRisk of deathMexican-American infantsLast pregnancyAlcohol intakePrenatal careMaternal ageMaternal raceInfant injuriesInfant's birth
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