2025
Quality of Care and Opportunities for Improvement in Prehospital Care of Critically Ill Pediatric Patients: An Observational, Simulation-Based Study
Cicero M, Schissler K, Baird J, Brown L, Auerbach M, Irgens-Moller N, Pavlinetz N, Adelgais K. Quality of Care and Opportunities for Improvement in Prehospital Care of Critically Ill Pediatric Patients: An Observational, Simulation-Based Study. Prehospital Emergency Care 2025, ahead-of-print: 1-10. PMID: 40353808, DOI: 10.1080/10903127.2025.2500715.Peer-Reviewed Original ResearchEmergency medical servicesPediatric emergency care coordinatorCare of critically ill pediatric patientsQuality of careProspective cohort studyCare coordinationPrehospital carePediatric simulationClinical skillsPrehospital scenariosEvaluate performance differencesMedical servicesSkills checklistTeam performanceCritically ill pediatric patientsPediatric emergenciesSkill performanceIll pediatric patientsClinicians informationSecondary objectivesStandard toolPediatric patientsAgency levelTeamSkills
2023
Gaps in pediatric emergency medicine education of emergency medicine residents: A needs assessment of recent graduates
Schoppel K, Spector J, Okafor I, Church R, Deblois K, Della‐Giustina D, Kellogg A, MacVane C, Pirotte M, Snow D, Hays G, Mariorenzi A, Connelly H, Sheng A. Gaps in pediatric emergency medicine education of emergency medicine residents: A needs assessment of recent graduates. AEM Education And Training 2023, 7: e10918. PMID: 38037628, PMCID: PMC10685395, DOI: 10.1002/aet2.10918.Peer-Reviewed Original ResearchPediatric patientsEmergency departmentCohort studyMortality outcomesCommunity-based emergency departmentNeonatal intensive care unitResidency trainingEM physiciansPediatric emergency medicine educationCommunity emergency departmentsIll pediatric patientsDescriptive cohort studyIntensive care unitPediatric cardiac arrestPediatric intensive careSurvey-based cohort studyEM residency trainingPediatric-specific educationPediatric-specific experienceEmergency medicine traineesDeidentified surveyCare unitPediatric wardTube thoracostomyEndotracheal intubationEvaluation of Pediatric Readiness Using Simulation in General Emergency Departments in a Medically Underserved Region
Rutledge C, Waddell K, Gaither S, Whitfill T, Auerbach M, Tofil N. Evaluation of Pediatric Readiness Using Simulation in General Emergency Departments in a Medically Underserved Region. Pediatric Emergency Care 2023, 40: 335-340. PMID: 37973039, DOI: 10.1097/pec.0000000000003056.Peer-Reviewed Original ResearchPediatric readiness scoreGeneral emergency departmentsPediatric patient volumeComposite quality scorePediatric patientsPediatric emergenciesEmergency departmentHigher composite quality scorePatient volumeNational Pediatric Readiness ProjectIll pediatric patientsUnderserved areasClinical care processesEmergency medical servicesPediatric readinessSimulated paediatric emergencyPediatric carePatientsCare processesHospital locationPediatric resourcesED locationMedical servicesUnderserved regionsSignificant differences
2022
What Laboratory Tests and Physiologic Triggers Should Guide the Decision to Administer a Platelet or Plasma Transfusion in Critically Ill Children and What Product Attributes Are Optimal to Guide Specific Product Selection? From the Transfusion and Anemia EXpertise Initiative–Control/Avoidance of Bleeding
Delaney M, Karam O, Lieberman L, Steffen K, Muszynski JA, Goel R, Bateman ST, Parker RI, Nellis ME, Remy KE, Network A. What Laboratory Tests and Physiologic Triggers Should Guide the Decision to Administer a Platelet or Plasma Transfusion in Critically Ill Children and What Product Attributes Are Optimal to Guide Specific Product Selection? From the Transfusion and Anemia EXpertise Initiative–Control/Avoidance of Bleeding. Pediatric Critical Care Medicine 2022, 23: e1-e13. PMID: 34989701, PMCID: PMC8769352, DOI: 10.1097/pcc.0000000000002854.Peer-Reviewed Original ResearchConceptsAnemia EXpertise Initiative-Control/AvoidanceIll pediatric patientsIll childrenPlasma transfusionPediatric patientsPlatelet transfusionsConsensus statementSystematic reviewLos Angeles Appropriateness MethodPhysiologic triggerExpert-based statementsCritically Ill ChildrenDevelopment/UniversityExpert consensus statementCochrane Library databasesBleeding expertsRecommendations AssessmentTransfusion managementAppropriateness MethodBlood productsLaboratory testingTransfusionLibrary databasesConsensus conferenceExpert consensusExecutive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative—Control/Avoidance of Bleeding (TAXI-CAB)
Nellis ME, Karam O, Valentine SL, Bateman ST, Remy KE, Lacroix J, Cholette JM, Bembea MM, Russell RT, Steiner ME, Goobie SM, Tucci M, Stricker PA, Stanworth SJ, Delaney M, Lieberman L, Muszynski JA, Bauer DF, Steffen K, Nishijima D, Ibla J, Emani S, Vogel AM, Haas T, Goel R, Crighton G, Delgado D, Demetres M, Parker RI, Network A. Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative—Control/Avoidance of Bleeding (TAXI-CAB). Pediatric Critical Care Medicine 2022, 23: 34-51. PMID: 34989711, PMCID: PMC8820267, DOI: 10.1097/pcc.0000000000002851.Peer-Reviewed Original ResearchConceptsIll pediatric patientsPlatelet transfusionsPediatric patientsIll childrenAnemia EXpertise Initiative-Control/AvoidanceSystematic reviewExpert-based consensusMultidisciplinary international expertsPlatelet transfusion practicesGrading of RecommendationsRisk of bleedingAdministration of plasmaConsensus-based statementsCochrane Library databasesEvidence-based recommendationsBest practice statementsClinical decision treeSubject Headings termsCritical illnessIll infantsTransfusion practicePediatric intensivistsConsensus statementTransfusionLibrary databases
2021
Epidemiology of Bleeding in Critically Ill Children With an Underlying Oncologic Diagnosis
Romano J, Martinez M, Levasseur J, Killinger JS, Karam O, Nellis ME. Epidemiology of Bleeding in Critically Ill Children With an Underlying Oncologic Diagnosis. Critical Care Explorations 2021, 3: e0572. PMID: 34746797, PMCID: PMC8565795, DOI: 10.1097/cce.0000000000000572.Peer-Reviewed Original ResearchSevere bleedingOncologic diagnosisIll childrenEpidemiology of BleedingPICU-free daysSevere bleeding eventsVentilator-free daysIll pediatric patientsMedian platelet countRetrospective cohort studyInternational normalized ratioBlood component therapyVulnerable patient populationComprehensive cancer centerBleeding eventsHemostatic medicationsPICU admissionPercent patientsTransplant statusCohort studyMedian agePediatric patientsExact epidemiologySevere thrombocytopeniaPlatelet countCreation of a standardized pediatric emergency medicine simulation curriculum for emergency medicine residents
Burns R, Madhok M, Bank I, Nguyen M, Falk M, Waseem M, Auerbach M. Creation of a standardized pediatric emergency medicine simulation curriculum for emergency medicine residents. AEM Education And Training 2021, 5: e10685. PMID: 34632245, PMCID: PMC8489268, DOI: 10.1002/aet2.10685.Peer-Reviewed Original ResearchIll pediatric patientsPediatric patientsEM residentsMajority of facilitatorsMajority of childrenEmergency departmentCare knowledgeEmergency medicine residentsResidency program graduatesResuscitation skillsMost facilitatorsMedicine residentsEmergency medicineSimulation-based curriculumEmergent assessmentMost participantsElectronic surveyPatientsEM traineesChildrenDelphi studyParticipantsSimulation curriculumFacilitatorsResidentsPerformance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial Heart and Lung Failure-Pediatric Insulin Titration Trial (HALF-PINT)
Hirshberg E, Alexander J, Asaro L, Coughlin-Wells K, Steil G, Spear D, Stone C, Nadkarni V, Agus M, Investigators H, Agus M, Wypij D, Asaro L, Nadkarni V, Srinivasan V, Biagas K, Mourani P, Chima R, Thomas N, Li S, Pinto A, Newth C, Hassinger A, Bysani K, Rehder K, Faustino E, Kandil S, Hirshberg E, Wintergerst K, Schwarz A, Bagdure D, Marsillio L, Cvijanovich N, Pham N, Quasney M, Flori H, Federman M, Nett S, Pinto N, Viteri S, Schneider J, Medar S, Sapru A, McQuillen P, Babbitt C, Lin J, Jouvet P, Yanay O, Allen C, Luckett P, Fackler J, Rozen T. Performance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial Heart and Lung Failure-Pediatric Insulin Titration Trial (HALF-PINT). CHEST Journal 2021, 160: 919-928. PMID: 33932465, PMCID: PMC8449010, DOI: 10.1016/j.chest.2021.04.049.Peer-Reviewed Original ResearchConceptsLung Failure-Pediatric INsulin Titration trialBlood glucose targetsCritical care trialsManagement of hyperglycemiaTitration trialCare trialsGlucose targetsCDS toolElectronic clinical decision support systemLow complianceBlood glucose metricsIll pediatric patientsObservational retrospective studyElectronic decision support systemClinical decision support systemInotropic supportPediatric patientsPatient factorsRetrospective studyClinician factorsIll childrenGlucose metricsPatientsTherapeutic interventionsStudy design
2017
Capnography Use During Intubation and Cardiopulmonary Resuscitation in the Pediatric Emergency Department
Bullock A, Dodington JM, Donoghue AJ, Langhan ML. Capnography Use During Intubation and Cardiopulmonary Resuscitation in the Pediatric Emergency Department. Pediatric Emergency Care 2017, 33: 457-461. PMID: 27455341, PMCID: PMC5259553, DOI: 10.1097/pec.0000000000000813.Peer-Reviewed Original ResearchConceptsCapnography useEmergency departmentHospital emergency departmentCardiopulmonary resuscitationSpontaneous circulationAHA recommendationsAcademic children's hospital emergency departmentChildren's hospital emergency departmentAmerican Heart Association guidelinesImplementation of capnographyIll pediatric patientsHeart Association guidelinesRetrospective chart reviewUse of capnographyPediatric emergency departmentChart reviewAdverse eventsPatient characteristicsPediatric patientsIntubated patientsEndotracheal intubationTraumatic causesAssociation guidelinesIll childrenPatients
2014
The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis
Giuliano JS, Tran K, Li FY, Shabanova V, Tala JA, Bhandari V. The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis. Pediatric Critical Care Medicine 2014, 15: e1-e8. PMID: 24141659, PMCID: PMC3947338, DOI: 10.1097/pcc.0b013e3182a553bb.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAngiopoietin-1Angiopoietin-2BiomarkersCase-Control StudiesChildChild, PreschoolFemaleHumansIntensive Care Units, PediatricLength of StayMalePredictive Value of TestsProspective StudiesSepsisSeverity of Illness IndexShock, SepticSystemic Inflammatory Response SyndromeTime FactorsConceptsSevere sepsis/shockSepsis/shockSystemic inflammatory response syndrome/sepsisPediatric patientsShock groupAngiopoietin-2Day 2Angiopoietin-1Days of illnessHours of admissionIll pediatric patientsInflammatory response syndromeRisk stratification scoresProspective observational studyCritical care physiciansVascular growth factorsEnzyme-linked immunosorbentAngiopoietin levelsPICU lengthPICU patientsSevere sepsisSepsis severityResponse syndromeStratification scoresCare physicians
2013
The SNAP index does not correlate with the State Behavioral Scale in intubated and sedated children
Thompson C, Shabanova V, Giuliano JS. The SNAP index does not correlate with the State Behavioral Scale in intubated and sedated children. Pediatric Anesthesia 2013, 23: 1174-1179. PMID: 24103039, PMCID: PMC3880626, DOI: 10.1111/pan.12258.Peer-Reviewed Original ResearchConceptsState Behavioral ScalePediatric intensive care unitSNAP indexSedation levelIll childrenIll pediatric patientsIntensive care unitLevel of sedationPediatric critical careBehavioral scalesIntravenous sedationPediatric patientsSNAP-IICare unitSBS scoresSubjective sedationBedside nursesSedated childrenCritical careObservational studySedationScoring toolInformed consentPatientsBrain activity
2008
Continuous end-tidal carbon dioxide monitoring in pediatric intensive care units
Langhan M. Continuous end-tidal carbon dioxide monitoring in pediatric intensive care units. Journal Of Critical Care 2008, 24: 227-230. PMID: 19327292, DOI: 10.1016/j.jcrc.2008.04.004.Peer-Reviewed Original ResearchConceptsPediatric intensive care unitIntensive care unitEnd-tidal carbon dioxide monitoringCare unitCarbon dioxide monitoringPercent of respondentsIntubated patientsPercent of directorsEndotracheal tube confirmationIll pediatric patientsContinuous End-Tidal Carbon Dioxide MonitoringAcid-base disturbancesCritical care fellowship programsTube confirmationNonintubated patientsPediatric patientsModerate sedationCardiopulmonary resuscitationCommon reasonPatientsClinical situationsWeb-based surveyClinical applicationUtilization patternsLack of availability
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