2023
A nested case-control study of serum zinc and incident diabetes among Chinese adults: Effect modifications and mediation analysis
Yang J, Cheng Z, Zhang D, Zheng T, Yin C, Liu S, Zhang L, Wang Z, Wang Y, Chen R, Dou Q, Bai Y. A nested case-control study of serum zinc and incident diabetes among Chinese adults: Effect modifications and mediation analysis. The Science Of The Total Environment 2023, 910: 168678. PMID: 37981151, DOI: 10.1016/j.scitotenv.2023.168678.Peer-Reviewed Original ResearchConceptsSerum zinc levelsRisk of diabetesCase-control studySerum zincDiabetes riskEffect modificationZinc levelsMediation proportionBaseline serum zinc concentrationPositive linear dose-response relationshipConditional logistic regression modelsHistory of hypertensionProspective population studyBody mass indexCoronary heart diseasePotential effect modificationSerum zinc concentrationLinear dose-response relationshipPopulation studiesDose-response relationshipLogistic regression modelsIncident diabetesHighest quartileMass indexFourth quartile
2021
Predictors of Time-in-Range (70–180 mg/dL) Achieved Using a Closed-Loop Control System
Schoelwer MJ, Kanapka LG, Wadwa RP, Breton MD, Ruedy KJ, Ekhlaspour L, Forlenza GP, Cobry EC, Messer LH, Cengiz E, Jost E, Carria L, Emory E, Hsu LJ, Weinzimer SA, Buckingham BA, Lal RA, Oliveri MC, Kollman CC, Dokken BB, Cherñavvsky DR, Beck RW, DeBoer MD, Gonder-Frederick L, Robic J, Voelmle M, Conschafter K, Morris K, Barnett C, Carr K, Hellmann J, Kime M, Todd Alonso G, Slover R, Berget C, Towers L, Lange S, Buckingham B, Maahs D, Lal R, Ekhlaspour L, Norlander L, Hood K, Town M, Weir C, Smith K, Hsu L, Shinksy D, Viana J, Cengiz E, Weinzimer S, Weyman K, Carria L, Zgorski M, Ruedy K, Beck R, Borgman S, Rusnak J, Kanapka L, Kollman C, Murphy C, Arreza-Rubin G, Green N, Kovatchev B, Brown S, Anderson S, Breton M, Laffel L, Pinsker J, Levy C, Kudva Y, Wadwa R, Buckingham B, Doyle III F, Renard E, Cobelli C, Reznik Y, Arreza-Rubin G, Lum J, Beck R, Ruedy K, Janicek R, Gabrielson D. Predictors of Time-in-Range (70–180 mg/dL) Achieved Using a Closed-Loop Control System. Diabetes Technology & Therapeutics 2021, 23: 475-481. PMID: 33689454, PMCID: PMC8252894, DOI: 10.1089/dia.2020.0646.Peer-Reviewed Original ResearchConceptsGlycemic controlLower TIROptimal glycemic controlType 1 diabetesPredictors of timeGreater improvementClinical characteristicsClinical predictorsFourth quartileMore insulinBody weightGlucose monitor dataExtension phaseMultivariate modelBolusStrongest predictorContinuous glucose monitor dataQuartileInsulinPredictorsChildrenParticipantsT1D.T1DDiabetes
2020
Does delay in time to surgery impact outcome in renal cell carcinoma: Analysis based on tumor size utilizing the National Cancer Database.
Patel D, Ghali F, Meagher M, Bradshaw A, Patel S, Murphy J, Derweesh I. Does delay in time to surgery impact outcome in renal cell carcinoma: Analysis based on tumor size utilizing the National Cancer Database. Journal Of Clinical Oncology 2020, 38: 664-664. DOI: 10.1200/jco.2020.38.6_suppl.664.Peer-Reviewed Original ResearchMultivariable Cox proportional hazardsNational Cancer DatabaseRenal cell carcinomaKaplan-Meier analysisYears of ageTumor sizeSurgery delayWorse OSOverall survivalHealthy patientsCell carcinomaCancer DatabaseLocalized Renal Cell CarcinomaNon-private insuranceTumor size 2Charlson comorbidity scoreCox proportional hazardsComorbidity scoreSurgical treatmentSurvival impactMedian timeEntire cohortFourth quartileBlack raceActive surveillance
2018
Treatment Times in Salivary Gland Cancer: National Patterns and Association with Survival
Morse E, Fujiwara RJT, Judson B, Mehra S. Treatment Times in Salivary Gland Cancer: National Patterns and Association with Survival. Otolaryngology 2018, 159: 283-292. PMID: 29460669, DOI: 10.1177/0194599818758020.Peer-Reviewed Original ResearchConceptsOverall survivalSalivary cancerTotal treatment packageMedian durationRT durationTreatment initiationRadiation treatmentTreatment characteristicsMultivariable Cox proportional hazards regressionCox proportional hazards regressionMultivariable binary logistic regressionNational Cancer DatabaseProportional hazards regressionSalivary gland cancerTreatment packageBinary logistic regressionTherapy durationInitial treatmentFacility volumeHazards regressionFourth quartileCare transitionsGland cancerInsurance statusCancer Database
2015
Soluble levels of CD27 and CD30 are associated with risk of non‐Hodgkin lymphoma in three Chinese prospective cohorts
Bassig BA, Shu XO, Koh WP, Gao YT, Purdue MP, Butler LM, Adams-Haduch J, Xiang YB, Kemp TJ, Wang R, Pinto LA, Zheng T, Ji BT, Hosgood HD, Hu W, Yang G, Zhang H, Chow WH, Kim C, Seow WJ, Zheng W, Yuan JM, Lan Q, Rothman N. Soluble levels of CD27 and CD30 are associated with risk of non‐Hodgkin lymphoma in three Chinese prospective cohorts. International Journal Of Cancer 2015, 137: 2688-2695. PMID: 26095604, PMCID: PMC4898881, DOI: 10.1002/ijc.29637.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaB cell activationProspective studyNHL riskWestern populationsChinese prospective cohortIntermediate endpoint biomarkersCase-control studySoluble CD30Prospective cohortSoluble CD27Fourth quartileBlood drawLowest quartileEndpoint biomarkersNHL casesImportant underlying mechanismChinese menSimilar associationSoluble levelsSCD27SCD30CD30CD27Underlying mechanismRegional-Level Correlations in Inappropriate Imaging Rates for Prostate and Breast Cancers: Potential Implications for the Choosing Wisely Campaign
Makarov DV, Soulos PR, Gold HT, Yu JB, Sen S, Ross JS, Gross CP. Regional-Level Correlations in Inappropriate Imaging Rates for Prostate and Breast Cancers: Potential Implications for the Choosing Wisely Campaign. JAMA Oncology 2015, 1: 185-194. PMID: 26181021, PMCID: PMC4707944, DOI: 10.1001/jamaoncol.2015.37.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBreast NeoplasmsCatchment Area, HealthChi-Square DistributionDiagnostic ImagingFemaleGuideline AdherenceHumansLogistic ModelsMaleMedicareMultivariate AnalysisPractice Guidelines as TopicPractice Patterns, Physicians'Predictive Value of TestsProstatic NeoplasmsResidence CharacteristicsRetrospective StudiesRisk FactorsSEER ProgramUnited StatesUnnecessary ProceduresConceptsLow-risk prostate cancerProstate cancerBreast cancerProstate cancer imagingFourth quartileLow-risk breast cancerBreast cancer imagingLow-risk prostateEnd Results-MedicareRetrospective cohort studyMultivariable logistic regressionChoosing Wisely campaignPatient-level analysisAppropriateness of careHospital referral regionsCancer imagingQuality of careInappropriate imagingCohort studyWisely campaignHealth care spendingLowest quartileOdds ratioPatient levelHRR level
2005
Impact of Managed Care on Cancer Trial Enrollment
Gross CP, Krumholz HM. Impact of Managed Care on Cancer Trial Enrollment. Journal Of Clinical Oncology 2005, 23: 3811-3818. PMID: 15923575, DOI: 10.1200/jco.2005.00.430.Peer-Reviewed Original ResearchConceptsTrial enrollment ratesCancer trial enrollmentTrial enrollmentCare penetrationCooperative group trialsLow enrollment ratesNational Cancer InstituteCounty characteristicsFourth quartileTrial participationLowest quartileProstate cancerCare competitionGroup trialsCancer InstituteStrong inverse correlationBivariate analysisCare activitiesMultivariate modelParticipant dataInverse correlationEnrollment ratesManaged CareZip codesQuartile
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