2008
Calpain5 expression is decreased in endometriosis and regulated by HOXA10 in human endometrial cells
Penna I, Du H, Ferriani R, Taylor HS. Calpain5 expression is decreased in endometriosis and regulated by HOXA10 in human endometrial cells. Molecular Human Reproduction 2008, 14: 613-618. PMID: 18829447, PMCID: PMC2734161, DOI: 10.1093/molehr/gan055.Peer-Reviewed Original ResearchConceptsEndometrial cellsGlandular cellsDevelopment of endometriosisHuman endometrial cellsExpression of HOXA10Real-time RT-PCRQuantitative real-time RT-PCRHOXA10 siRNAEndometrial biopsyEpithelial cell lineDecidual samplesEutopic endometriumMenstrual cyclePregnancy terminationEndometriosisFertile controlsHOXA10 expressionDecreased expressionRT-PCRProtein expressionRespective controlsHOXA10BiopsyCell linesAberrant regulation
2007
Occupational and environmental exposures to heavy metals: Risk factors for male infertility in Lebanon?
Inhorn M, King L, Nriagu J, Kobeissi L, Hammoud N, Awwad J, Abu-Musa A, Hannoun A. Occupational and environmental exposures to heavy metals: Risk factors for male infertility in Lebanon? Reproductive Toxicology 2007, 25: 203-212. PMID: 18093800, DOI: 10.1016/j.reprotox.2007.10.011.Peer-Reviewed Original ResearchConceptsMale infertilityRisk factorsBlood concentrationsFertile controlsRisk Factor InterviewEnvironmental exposuresImportant risk factorCase-control studyHigher whole-blood concentrationsWhole blood concentrationsUnexposed menInfertile casesReferent populationOccupational exposureInfertile menHealthy individualsFertility clinicsSemen analysisBlood collectionInfertilityMultiple regression analysisRegression analysisMenExposureClinicCivil war and male infertility in Lebanon
Kobeissi L, Inhorn M, Hannoun A, Hammoud N, Awwad J, Abu-Musa A. Civil war and male infertility in Lebanon. Fertility And Sterility 2007, 90: 340-345. PMID: 17919611, DOI: 10.1016/j.fertnstert.2007.06.061.Peer-Reviewed Original Research
2006
Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx
Daftary GS, Kayisli U, Seli E, Bukulmez O, Arici A, Taylor HS. Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx. Fertility And Sterility 2006, 87: 367-372. PMID: 17173899, DOI: 10.1016/j.fertnstert.2006.06.041.Peer-Reviewed Original ResearchConceptsEndometrial HOXA10 expressionImplantation rateHOXA10 expressionInfertile womenFertile controlsHOXA10 mRNAPolymerase chain reaction findingsProspective clinical trialsReal-time reverse transcription-polymerase chain reactionReverse transcription-polymerase chain reactionHOXA10 protein expressionExpression of HOXA10Academic medical centerHOXA10 mRNA expressionGlandular epithelial cellsHomeobox gene HOXA10Potential molecular mechanismsBilateral hydrosalpinxHydrosalpinx fluidEndometrial stromaMidluteal phasePolymerase chain reactionClinical trialsSalpingectomyMedical Center
2005
Removal of hydrosalpinges increases endometrial leukaemia inhibitory factor (LIF) expression at the time of the implantation window
Seli E, Kayisli UA, Cakmak H, Bukulmez O, Bildirici I, Guzeloglu-Kayisli O, Arici A. Removal of hydrosalpinges increases endometrial leukaemia inhibitory factor (LIF) expression at the time of the implantation window. Human Reproduction 2005, 20: 3012-3017. PMID: 16024536, DOI: 10.1093/humrep/dei188.Peer-Reviewed Original ResearchConceptsLeukemia inhibitory factorInfertile womenLIF expressionFertile controlsExpression of LIFLeukemia inhibitory factor expressionAdverse effectsEndometrial LIF expressionPresence of hydrosalpingesWindow of implantationIVF-embryo transferGlandular epithelial cellsWestern blot findingsLIF immunoreactivityLIF levelsEndometrial receptivityEndometrial expressionImplantation windowPregnancy rateHydrosalpingesSalpingectomyImmunohistochemical analysisLow implantationInhibitory factorFactor expression
2003
Endometrial HOXA10 expression after controlled ovarian hyperstimulation with recombinant follicle-stimulating hormone
Taylor HS, Daftary GS, Selam B. Endometrial HOXA10 expression after controlled ovarian hyperstimulation with recombinant follicle-stimulating hormone. Fertility And Sterility 2003, 80: 839-843. PMID: 14505762, DOI: 10.1016/s0015-0282(03)00985-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmbryo ImplantationEndometriumEstradiolFemaleFertility Agents, FemaleFollicle Stimulating HormoneGonadotropin-Releasing HormoneHomeobox A10 ProteinsHomeodomain ProteinsHormone AntagonistsHumansLeuprolideOvulation InductionProspective StudiesRecombinant ProteinsReverse Transcriptase Polymerase Chain ReactionRNATumor Cells, CulturedConceptsEndometrial HOXA10 expressionOvarian hyperstimulationRecombinant FSHReverse transcriptase-polymerase chain reactionGnRH agonistGnRH antagonistHOXA10 expressionFertile controlsRecombinant follicle-stimulating hormoneCycle day 21Pipelle endometrial biopsyFollicle-stimulating hormoneQuantitative reverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionAcademic medical centerDose-dependent mannerEndometrial biopsyEndometrial receptivityProspective studyIshikawa cellsMedical CenterHyperstimulationMAIN OUTCOMEFSHDay 21
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