2008
Decreased endometrial HOXA10 expression associated with use of the copper intrauterine device
Tetrault AM, Richman SM, Fei X, Taylor HS. Decreased endometrial HOXA10 expression associated with use of the copper intrauterine device. Fertility And Sterility 2008, 92: 1820-1824. PMID: 18930214, PMCID: PMC2811037, DOI: 10.1016/j.fertnstert.2008.08.134.Peer-Reviewed Original ResearchConceptsEndometrial HOXA10 expressionCopper intrauterine deviceIntrauterine deviceHOXA10 expressionBiopsy samplesEndometrial receptivityEndometrial biopsy samplesNormal cycling womenCase-control studyExpression of HOXA10Academic medical centerMean H-scoreGlandular expressionIUD contraceptivesHormonal contraceptivesCycling womenContraceptive efficacyIUD useMedical CenterIUD usersMAIN OUTCOMEImmunohistochemical analysisH-scoreEndometrial HOXA10WomenSubmucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity
Rackow BW, Taylor HS. Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity. Fertility And Sterility 2008, 93: 2027-2034. PMID: 18555231, PMCID: PMC3107853, DOI: 10.1016/j.fertnstert.2008.03.029.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkers, TumorCase-Control StudiesEmbryo ImplantationEndometriumFemaleGene Expression Regulation, NeoplasticHomeobox A10 ProteinsHomeodomain ProteinsHumansInfertility, FemaleKruppel-Like Transcription FactorsLeiomyomaLeukemia Inhibitory FactorMiddle AgedMucous MembranePrognosisUterine NeoplasmsConceptsReal-time reverse transcriptase-polymerase chain reactionSubmucosal myomasEndometrial receptivityUterine leiomyomaMRNA expressionEndometrial HOXA10 expressionSubmucosal uterine leiomyomasLIF mRNA expressionReproductive-aged womenTime of surgeryCase-control studyReverse transcriptase-polymerase chain reactionHOXA10 protein expressionQuantitative real-time reverse transcriptase-polymerase chain reactionUniversity Medical CenterTranscriptase-polymerase chain reactionMessenger RNA expressionReal-time RT-PCREndometrial samplingPrimary endpointEndometrial biopsyUterine myomaIntramural myomasMedical CenterReproductive dysfunctionGnRH antagonists may affect endometrial receptivity
Rackow BW, Kliman HJ, Taylor HS. GnRH antagonists may affect endometrial receptivity. Fertility And Sterility 2008, 89: 1234-1239. PMID: 18410932, PMCID: PMC2699407, DOI: 10.1016/j.fertnstert.2007.04.060.Peer-Reviewed Original ResearchConceptsGnRH antagonistEndometrial stromal cellsEndometrial receptivityHOXA10 protein expressionHOXA10 expressionGnRH agonistControl subjectsProspective case-control studyStromal cellsEndometrial HOXA10 expressionPipelle endometrial biopsyProtein expressionSpontaneous LH surgeCase-control studyAcademic medical centerNatural cycleOvarian hyperstimulationRecombinant FSHEndometrial biopsyHCG administrationUntreated cyclesEndometrial glandsLH surgeMedical CenterMAIN OUTCOME
2006
Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx
Daftary GS, Kayisli U, Seli E, Bukulmez O, Arici A, Taylor HS. Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx. Fertility And Sterility 2006, 87: 367-372. PMID: 17173899, DOI: 10.1016/j.fertnstert.2006.06.041.Peer-Reviewed Original ResearchConceptsEndometrial HOXA10 expressionImplantation rateHOXA10 expressionInfertile womenFertile controlsHOXA10 mRNAPolymerase chain reaction findingsProspective clinical trialsReal-time reverse transcription-polymerase chain reactionReverse transcription-polymerase chain reactionHOXA10 protein expressionExpression of HOXA10Academic medical centerHOXA10 mRNA expressionGlandular epithelial cellsHomeobox gene HOXA10Potential molecular mechanismsBilateral hydrosalpinxHydrosalpinx fluidEndometrial stromaMidluteal phasePolymerase chain reactionClinical trialsSalpingectomyMedical Center
2004
EMX2 Gene Expression in the Female Reproductive Tract and Aberrant Expression in the Endometrium of Patients with Endometriosis
Daftary GS, Taylor HS. EMX2 Gene Expression in the Female Reproductive Tract and Aberrant Expression in the Endometrium of Patients with Endometriosis. The Journal Of Clinical Endocrinology & Metabolism 2004, 89: 2390-2396. PMID: 15126568, DOI: 10.1210/jc.2003-031389.Peer-Reviewed Original ResearchMeSH KeywordsAdultBinding SitesCells, CulturedDNA-Binding ProteinsEndometriosisEndometriumFemaleGene ExpressionGenitalia, FemaleHomeobox A10 ProteinsHomeodomain ProteinsHumansMenstrual CycleOligonucleotides, AntisenseProtein Structure, TertiaryRNA, MessengerStromal CellsTranscription FactorsTranscription, GeneticConceptsEndometrium of patientsPeriimplantation endometriumHOXA10 expressionMenstrual cycle-dependent expressionPrimary endometrial stromal cellsStromal cellsEndometrial HOXA10 expressionAbsence of endometriosisEndometrial stromal cellsEMX2 expressionReproductive tract developmentFemale reproductive tractHOXA10 antisenseHOXA10 levelsNormal endometriumSex steroidsEndometriosisEndometriumPeriimplantation periodEndometrial HOXA10Proliferative phaseReproductive tractAberrant expressionTract developmentMRNA levels
2003
Pleiotropic effects of Hoxa10 on the functional development of peri‐implantation endometrium
Daftary GS, Taylor HS. Pleiotropic effects of Hoxa10 on the functional development of peri‐implantation endometrium. Molecular Reproduction And Development 2003, 67: 8-14. PMID: 14648870, DOI: 10.1002/mrd.20013.Peer-Reviewed Original ResearchConceptsEndometrial receptivityOvariectomized miceEndometrial differentiationEndometrial HOXA10 expressionPeri-implantation endometriumHigh progesterone levelsAdditional control miceEosinophil infiltrationProgestational effectsUterine weightControl miceProgesterone treatmentProgesterone levelsEndometrial epitheliumOvarian progesteroneSpecific differentiation markersEmbryo implantationUterine endometriumHOXA10 expressionProgesteroneMiceEstrogenRegenerative adult tissuesFunctional differentiationVector pcDNA3.1Endometrial HOXA10 expression after controlled ovarian hyperstimulation with recombinant follicle-stimulating hormone
Taylor HS, Daftary GS, Selam B. Endometrial HOXA10 expression after controlled ovarian hyperstimulation with recombinant follicle-stimulating hormone. Fertility And Sterility 2003, 80: 839-843. PMID: 14505762, DOI: 10.1016/s0015-0282(03)00985-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmbryo ImplantationEndometriumEstradiolFemaleFertility Agents, FemaleFollicle Stimulating HormoneGonadotropin-Releasing HormoneHomeobox A10 ProteinsHomeodomain ProteinsHormone AntagonistsHumansLeuprolideOvulation InductionProspective StudiesRecombinant ProteinsReverse Transcriptase Polymerase Chain ReactionRNATumor Cells, CulturedConceptsEndometrial HOXA10 expressionOvarian hyperstimulationRecombinant FSHReverse transcriptase-polymerase chain reactionGnRH agonistGnRH antagonistHOXA10 expressionFertile controlsRecombinant follicle-stimulating hormoneCycle day 21Pipelle endometrial biopsyFollicle-stimulating hormoneQuantitative reverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionAcademic medical centerDose-dependent mannerEndometrial biopsyEndometrial receptivityProspective studyIshikawa cellsMedical CenterHyperstimulationMAIN OUTCOMEFSHDay 21
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