2024
The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression
Jiang R, Noble S, Rosenblatt M, Dai W, Ye J, Liu S, Qi S, Calhoun V, Sui J, Scheinost D. The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression. Nature Communications 2024, 15: 4411. PMID: 38782943, PMCID: PMC11116547, DOI: 10.1038/s41467-024-48827-8.Peer-Reviewed Original ResearchConceptsIncident depressionPre-frailPhysical frailtyFrail individualsPopulation attributable fraction analysisRisk factors of depressionMendelian randomization analysisFactors of depressionPotential causal effectModifiable risk factorsNon-frail individualsCross-sectional studyEffect of frailtyHigher disease burdenUK BiobankRandomization analysisBrain volumeDepression casesDisease burdenFrailtyRegional brain volumesIncreased riskDepressionHigh riskFollow-up
2016
The prevalence and associated factors of depression in policing: a cross sectional study in Sri Lanka
Wickramasinghe ND, Wijesinghe PR, Dharmaratne SD, Agampodi SB. The prevalence and associated factors of depression in policing: a cross sectional study in Sri Lanka. SpringerPlus 2016, 5: 1776. PMID: 27795918, PMCID: PMC5061667, DOI: 10.1186/s40064-016-3474-9.Peer-Reviewed Original ResearchPrevalence of depressionSectional studyOccupational factorsMultivariable logistic regressionCross-sectional studyFactors of depressionPackage of interventionsMental health disturbancesMental health problemsPotential traumatic eventsConclusionsThe prevalenceHigh-risk professionsMultivariable analysisPoint prevalenceMean ageAssociated FactorsDepression ScaleResponse rateHealth problemsHealth disturbancesModifiable natureBivariate analysisLogistic regressionPrevalenceDepression
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