2025
Is university attendance associated with differences in health service use for a mental health problem in emerging adulthood? Evidence from the ALSPAC population-based cohort
Osborn T, Saunders R, Fonagy P. Is university attendance associated with differences in health service use for a mental health problem in emerging adulthood? Evidence from the ALSPAC population-based cohort. Social Psychiatry And Psychiatric Epidemiology 2025, 1-14. PMID: 40389705, DOI: 10.1007/s00127-025-02922-3.Peer-Reviewed Original ResearchHealth service useMental health problemsAssociated with health service useService useHealth problemsAvon Longitudinal Study of ParentsMultiple imputationLongitudinal Study of ParentsAvon Longitudinal StudyMaternal education levelPopulation-based cohortStudy of parentsRobustness of associationsLogistic regression modelsHealth servicesSTROBE guidelinesConfounder adjustmentAnalytic sampleEducation levelALSPACMental disordersAttend universityEmerging adulthoodStudy protocolHealthFloods and cause-specific mortality in the United States applying a triply robust approach
Chu L, Warren J, Spatz E, Lowe S, Lu Y, Ma X, Ross J, Krumholz H, Chen K. Floods and cause-specific mortality in the United States applying a triply robust approach. Nature Communications 2025, 16: 2853. PMID: 40122917, PMCID: PMC11930965, DOI: 10.1038/s41467-025-58236-0.Peer-Reviewed Original ResearchConceptsCDC's National Center for Health StatisticsNational Center for Health StatisticsCause-specific mortality ratesCenter for Health StatisticsCause-specific mortalityHealth impacts of floodingExcess all-cause deathsLong-term health risksFlood daysLong-term associationDeath recordsHealth StatisticsConfounder adjustmentExternal causesStorm Events DatabaseAll-cause deathHealth impactsImpact of floodsPropensity scorePost‐flood yearMortality rateMyocardial infarctionPost-floodContiguous U.S.Respiratory disease
2024
Ursodeoxycholic acid and severe COVID-19 outcomes in a cohort study using the OpenSAFELY platform
Costello R, Waller K, Smith R, Mells G, Wong A, Schultze A, Mahalingasivam V, Herrett E, Zheng B, Lin L, MacKenna B, Mehrkar A, Bacon S, Goldacre B, Tomlinson L, Tazare J, Rentsch C. Ursodeoxycholic acid and severe COVID-19 outcomes in a cohort study using the OpenSAFELY platform. Communications Medicine 2024, 4: 238. PMID: 39562612, PMCID: PMC11576861, DOI: 10.1038/s43856-024-00664-y.Peer-Reviewed Original ResearchCOVID-19 hospitalisationSevere COVID-19 outcomesCOVID-19 related hospitalisationCOVID-19 outcomesCohort studyPopulation-based cohort studyHazard ratioPrimary care recordsDeath registration dataOpenSAFELY-TPP platformApproval of NHS EnglandConfidence intervalsEstimate hazard ratiosCox proportional hazards regressionProportional hazards regressionPre-specified confoundersAbsolute risk reductionOpenSAFELY platformCare recordsNHS EnglandConfounder adjustmentEligible individualsRegistration dataHazards regressionHospital records
2021
Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta‐analysis
Kim J, Choi M, Ha S, Hwang J, Koyanagi A, Dragioti E, Radua J, Smith L, Jacob L, de Pablo G, Lee S, Yon D, Thompson T, Cortese S, Lollo G, Liang C, Chu C, Fusar‐Poli P, Cheon K, Shin J, Solmi M. Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta‐analysis. Autism Research 2021, 15: 340-352. PMID: 34939353, DOI: 10.1002/aur.2656.Peer-Reviewed Original ResearchConceptsSystematic reviewTemporal sequencing of diagnosesIncident inflammatory bowel diseaseMeta-analysisPublication biasCo-occurring medical conditionsHigher risk of inflammatory bowel diseaseRisk of inflammatory bowel diseaseRandom-effects meta-analysisInflammatory bowel diseaseQuality of studiesNewcastle-Ottawa ScaleSequence of diagnosisMeta-regression analysisConfounder adjustmentBowel diseaseAssess heterogeneityNewcastle-OttawaStudy designMeta-RegressionMedical conditionsPrimary outcomeAutism spectrum disorderBiological mechanismsObservational study
2020
Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2
Salinas YD, Wang Z, DeWan AT. Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2. American Journal Of Epidemiology 2020, 190: 85-94. PMID: 32700739, PMCID: PMC7784522, DOI: 10.1093/aje/kwaa144.Peer-Reviewed Original ResearchConceptsBody mass indexMass indexComorbidity of asthmaWhite British subjectsCross-phenotype associationsAdult asthmaAsthma diagnosisAsthmaConfounder adjustmentAsthma associationsBMI associationsMediation analysisLimited evidenceCandidate gene studiesBMIObesityUK BiobankAssociationDiagnosisTwin studiesAgeFurther characterizationComorbiditiesConfounders
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