2025
Developmental timing of index trauma exposure and accelerated epigenetic aging in United States military veterans
Tamman A, Nagamatsu S, Cabrera-Mendoza B, Averill L, Dunn E, Krystal J, Gelernter J, Montalvo-Ortiz J, Polimanti R, Pietrzak R. Developmental timing of index trauma exposure and accelerated epigenetic aging in United States military veterans. Psychoneuroendocrinology 2025, 182: 107568. PMID: 41016323, DOI: 10.1016/j.psyneuen.2025.107568.Peer-Reviewed Original ResearchUnited States military veteransTrauma typesTrauma exposureMilitary veteransNational Health and ResilienceExposure to interpersonal violenceInterpersonal violenceNon-interpersonal traumaVeterans StudySelf-reported ageTrauma characteristicsEpigenetic ageTrauma burdenVeteransChronological ageGrimAgeViolenceGreater oddsDevelopmental timeTraumaYounger ageRecencyLong-term health risksPotential confoundersAgePrenatal opioid exposure alters pain perception and increases long-term health risks in infants with neonatal opioid withdrawal syndrome
Radhakrishna U, Radhakrishnan R, Uppala L, Trivedi T, Prajapati J, Rawal R, Muvvala S, Bahado-Singh R, Sadhasivam S. Prenatal opioid exposure alters pain perception and increases long-term health risks in infants with neonatal opioid withdrawal syndrome. Frontiers In Pain Research 2025, 6: 1497801. PMID: 40313396, PMCID: PMC12043715, DOI: 10.3389/fpain.2025.1497801.Peer-Reviewed Original ResearchNeonatal opioid withdrawal syndromeOpioid-exposed infantsOpioid withdrawal syndromePain-related genesOpioid exposureWithdrawal syndromeChronic painEpigenetic changesMaternal opioid exposurePrenatal opioid exposureImprove pain managementIon channel functionIllumina Infinium Methylation EPIC BeadChipInfinium Methylation EPIC BeadChipAnalyzed DNA methylationUnexposed control subjectsLong-term health risksPain reliefPain perceptionPregnant womenGnRH secretionPlacental tissueMorphine addictionHealth of mothersControl subjectsFloods and cause-specific mortality in the United States applying a triply robust approach
Chu L, Warren J, Spatz E, Lowe S, Lu Y, Ma X, Ross J, Krumholz H, Chen K. Floods and cause-specific mortality in the United States applying a triply robust approach. Nature Communications 2025, 16: 2853. PMID: 40122917, PMCID: PMC11930965, DOI: 10.1038/s41467-025-58236-0.Peer-Reviewed Original ResearchConceptsCDC's National Center for Health StatisticsNational Center for Health StatisticsCause-specific mortality ratesCenter for Health StatisticsCause-specific mortalityHealth impacts of floodingExcess all-cause deathsLong-term health risksFlood daysLong-term associationDeath recordsHealth StatisticsConfounder adjustmentExternal causesStorm Events DatabaseAll-cause deathHealth impactsImpact of floodsPropensity scorePost‐flood yearMortality rateMyocardial infarctionPost-floodContiguous U.S.Respiratory disease
2022
Electronic Nicotine Delivery Systems: An Updated Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology
Herbst RS, Hatsukami D, Acton D, Giuliani M, Moushey A, Phillips J, Sherwood S, Toll BA, Viswanath K, Warren NJH, Warren GW, Alberg AJ. Electronic Nicotine Delivery Systems: An Updated Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology. Journal Of Clinical Oncology 2022, 40: 4144-4155. PMID: 36287017, DOI: 10.1200/jco.22.01749.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsTobacco useENDS useCombustible tobaccoLong-term health risksEvidence-based treatmentsSurgeon General's ReportPublic healthNicotine delivery systemsTobacco-related disparitiesCombustible tobacco useBlood pressureSmoking cessationTobacco cessationCancer incidenceSmoking relapseClinical OncologyEpidemiological studiesImmune systemPotential efficacyE-cigarettesBrain developmentCancer developmentTobacco productsLongitudinal studyElectronic Nicotine Delivery Systems: An Updated Policy Statement from the American Association for Cancer Research and the American Society of Clinical Oncology
Herbst RS, Hatsukami D, Acton D, Giuliani M, Moushey A, Phillips J, Sherwood S, Toll BA, Viswanath K, Warren NJH, Warren GW, Alberg AJ. Electronic Nicotine Delivery Systems: An Updated Policy Statement from the American Association for Cancer Research and the American Society of Clinical Oncology. Clinical Cancer Research 2022, 28: of1-of10. PMID: 36287033, DOI: 10.1158/1078-0432.ccr-22-2429.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsTobacco useENDS useCombustible tobaccoLong-term health risksEvidence-based treatmentsSurgeon General's ReportPublic healthNicotine delivery systemsTobacco-related disparitiesCombustible tobacco useBlood pressureSmoking cessationTobacco cessationCancer incidenceSmoking relapseClinical OncologyEpidemiological studiesImmune systemPotential efficacyE-cigarettesBrain developmentCancer developmentTobacco productsLongitudinal study
2015
The effects of alcohol-containing e-cigarettes on young adult smokers
Valentine GW, Jatlow PI, Coffman M, Nadim H, Gueorguieva R, Sofuoglu M. The effects of alcohol-containing e-cigarettes on young adult smokers. Drug And Alcohol Dependence 2015, 159: 272-276. PMID: 26778759, PMCID: PMC5171208, DOI: 10.1016/j.drugalcdep.2015.12.011.Peer-Reviewed Original ResearchConceptsSubjective drug effectsE-cigarettesDrug effectsAlcohol metabolitesPlasma alcohol levelsUrine ethyl glucuronideLong-term health risksYoung adult smokersAlcohol conditionE-liquidsAcute safetyAdult smokersNicotine intakeAcute changesSafety dataNicotine addictionCrossover designBiochemical measuresAlcohol levelsPsychomotor performanceElectronic cigarettesDexterity testVulnerable populationsEthyl glucuronideMotor performance
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