2025
The Longitudinal Course of Physical Activity Behavior Poststroke and its Variation across Subgroups: The nor-COAST Study
Luzum G, Allore H, Han L, Saltvedt I, Tan X, Thingstad P, Håberg A, Askim T. The Longitudinal Course of Physical Activity Behavior Poststroke and its Variation across Subgroups: The nor-COAST Study. Physical Therapy 2025, pzaf069. PMID: 40360170, DOI: 10.1093/ptj/pzaf069.Peer-Reviewed Original ResearchLight physical activityModerate physical activitySit-to-stand transitionsPhysical activityStep countsUpright timeAverage daily step countDaily step countSit-to-standProfessional follow-upMulti-trajectory modelingCohort study designLong-term rehabilitationFollow-upSubgroups of peoplePA behaviorPA durationLongitudinal coursePA patternsLow PACommunity-BasedPA dimensionsPoststrokeAccelerometer dataStudy design
2024
Association of binge alcohol use with functional outcomes among individuals with COVID-19 infection
Tong S, Gottlieb M, Mannan I, Zheng Z, Sinha M, Santangelo M, Gatling K, Kean E, Watts P, Wang R, Montoy J, Idris A, MacDonald S, Huebinger R, Hill M, O’Laughlin K, Gentile N, Dorney J, Malicki C, Elmore J, Roldan K, Chan G, Lin Z, Weinstein R, Stephens K. Association of binge alcohol use with functional outcomes among individuals with COVID-19 infection. Alcohol And Alcoholism 2024, 60: agae086. PMID: 39745829, PMCID: PMC11694663, DOI: 10.1093/alcalc/agae086.Peer-Reviewed Original ResearchConceptsBinge alcohol usePhysical function outcomesFunctional outcomesAlcohol useBinge drinkingPatient-Reported Outcomes Measurement Information SystemCOVID-19 infectionSocial determinants of healthOutcomes Measurement Information SystemDeterminants of healthMeasurement Information SystemLong-term functional outcomeGeneralized Estimating Equation modelsExcessive alcohol intakeCohort study designFrequency of binge drinkingSelf-reported binge drinkingPain interferenceSocial determinantsPhysical functionPhysical healthTime of infectionPrescription medicationsAlcohol intakeAlcohol consumptionPharmacoepidemiology evaluation of bumetanide as a potential candidate for drug repurposing for Alzheimer's disease
Morales J, Gabriel N, Natarajan L, LaCroix A, Shadyab A, Xu R, Silverman J, Feldman H, Hernandez I, Aslanyan V, Bang A, Bevins E, Bowman G, Boyarko B, Chen X, Clelland C, Dodge H, Durant J, Edland S, Evans A, Galasko D, Gerwick W, Greenberg B, Herman M, Herold T, Hook V, Jacobs D, Kaye J, Kim D, Koo E, Kosik K, Léger G, Lupo J, Messer K, Momper J, Nygaard H, Pa J, Quinti L, Revta C, Rexach J, Rizzo S, Rynearson K, Schneider L, Slusher B, Tanzi R, Territo P, Yokoyama J. Pharmacoepidemiology evaluation of bumetanide as a potential candidate for drug repurposing for Alzheimer's disease. Alzheimer's & Dementia 2024, 20: 5236-5246. PMID: 39030734, PMCID: PMC11350022, DOI: 10.1002/alz.13872.Peer-Reviewed Original ResearchRisk of ADCross-sectional analysis of electronic health recordsAnalysis of electronic health recordsAD riskAssociated with risk of ADAssociated with AD riskAssociated with decreased prevalenceElectronic health recordsRetrospective cohort study designMedicare claims dataCohort study designCox proportional hazards regressionAssociated with riskCross-sectional analysisProportional hazards regressionPrevalence of ADMultiple sensitivity analysesAlzheimer's diseaseHealth recordsMedicare beneficiariesMedicare dataClaims dataStudy designHazards regressionPatient characteristics
2023
Gene mutations as a non-invasive measure of adult cochlear implant performance: Variable outcomes in patients with select TMPRSS3 mutations
Cottrell J, Dixon P, Cao X, Kiss A, Smilsky K, Kaminskas K, Ng A, Shipp D, Dimitrijevic A, Chen J, Lin V, Kyriakopoulou L, Le T. Gene mutations as a non-invasive measure of adult cochlear implant performance: Variable outcomes in patients with select TMPRSS3 mutations. PLOS ONE 2023, 18: e0291600. PMID: 37713394, PMCID: PMC10503761, DOI: 10.1371/journal.pone.0291600.Peer-Reviewed Original ResearchConceptsCochlear implantationHearing lossSevere-to-profound sensorineural hearing lossSpeech perception performanceSpeech perception scoresCochlear implant performanceProspective cohort study designCochlear implant patientsNon-syndromic hearing lossSensorineural hearing lossPathogenic variantsCohort study designPathogenic mutationsGene mutationsCI outcomesCI performanceCI patientsPerception performanceGenetic mutationsTMPRSS3 mutationsPerception scoresAssessed pre-Post-operative outcomesStudy designMonths post-operatively
2022
Copy number variants and fetal growth in stillbirths
Dalton S, Workalemahu T, Allshouse A, Page J, Reddy U, Saade G, Pinar H, Goldenberg R, Dudley D, Silver R. Copy number variants and fetal growth in stillbirths. American Journal Of Obstetrics And Gynecology 2022, 228: 579.e1-579.e11. PMID: 36356697, PMCID: PMC10149588, DOI: 10.1016/j.ajog.2022.11.1274.Peer-Reviewed Original ResearchConceptsAbnormal copy number variantsFetal growth abnormalitiesGestational ageOdds ratioStillbirth Collaborative Research NetworkGenetic abnormalitiesChromosomal microarrayGestational age outcomesGestational age infantsGrowth abnormalitiesClinical risk factorsCohort study designAdjusted odds ratioCopy number variantsUnknown clinical significancePathogenic copy number variantsPlacental insufficiencyAge infantsNumber variantsFetal growthMaternal ageRisk factorsClinical significanceHigh incidenceStillbirthHypertensive disorders during pregnancy and polycystic ovary syndrome are associated with child communication and social skills in a sex-specific and androgen-dependent manner
Firestein MR, Romeo RD, Winstead H, Goldman DA, Grobman WA, Haas DM, Parry S, Reddy UM, Silver RM, Wapner RJ, Champagne FA. Hypertensive disorders during pregnancy and polycystic ovary syndrome are associated with child communication and social skills in a sex-specific and androgen-dependent manner. Frontiers In Endocrinology 2022, 13: 1000732. PMID: 36246897, PMCID: PMC9559211, DOI: 10.3389/fendo.2022.1000732.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeHyperandrogenic disordersOvary syndromeMaternal testosteroneHypertensive disordersNulliparous Pregnancy Outcomes StudyCohort study designPregnancy Outcomes StudyYears of ageAutism spectrum disorderSex-specific associationsHigher testosterone levelsChildren's brain developmentNeurodevelopmental outcomesAndrogen-dependent mannerSecond trimesterPrenatal exposureMonitoring MothersTestosterone levelsOutcome studiesPregnancyFemale controlsMaternal plasmaTestosteroneChild communication
2018
Sexual orientation differences in outpatient psychiatric treatment and antidepressant usage: evidence from a population-based study of siblings
Bränström R, Hatzenbuehler ML, Tinghög P, Pachankis JE. Sexual orientation differences in outpatient psychiatric treatment and antidepressant usage: evidence from a population-based study of siblings. European Journal Of Epidemiology 2018, 33: 591-599. PMID: 29766438, PMCID: PMC5995973, DOI: 10.1007/s10654-018-0411-y.Peer-Reviewed Original ResearchConceptsOutpatient psychiatric treatmentMood disordersPsychiatric treatmentDisorder treatmentOutpatient health care visitsGreater likelihoodPopulation-based health surveyLongitudinal cohort study designStockholm Public Health CohortRandom population-based sampleAntidepressant medication usageSubstance use disorder treatmentHealth care visitsCohort study designHealth registry dataPopulation-based studyPrescription drug usePsychiatric outpatient treatmentUse disorder treatmentPopulation-based sampleHealth record dataCertain psychiatric disordersPsychiatric disorders treatmentCare visitsMedication usage
2017
Risk for hepatitis B and C virus reactivation in patients with psoriasis on biologic therapies: A retrospective cohort study and systematic review of the literature
Snast I, Atzmony L, Braun M, Hodak E, Pavlovsky L. Risk for hepatitis B and C virus reactivation in patients with psoriasis on biologic therapies: A retrospective cohort study and systematic review of the literature. Journal Of The American Academy Of Dermatology 2017, 77: 88-97.e5. PMID: 28495497, DOI: 10.1016/j.jaad.2017.01.037.Peer-Reviewed Original ResearchConceptsChronic HBV infectionBiologic therapyHBV infectionViral reactivationAntiviral prophylaxisCore antibodyHCV infectionHepatitis BSafety of biologic therapiesHistory of viral hepatitisSystematic reviewIsolated core antibodyHBV core antibodyLow-risk patientsRetrospective cohort study designRetrospective cohort studyReactivated HBV infectionCohort study designPsoriasis patientsViral hepatitisEvaluate safetyFollow-upCohort studyPrimary outcomeTreatment durationOne-Year Incidence and Predictors of Homelessness Among 300,000 U.S. Veterans Seen in Specialty Mental Health Care
Tsai J, Hoff RA, Harpaz-Rotem I. One-Year Incidence and Predictors of Homelessness Among 300,000 U.S. Veterans Seen in Specialty Mental Health Care. Psychological Services 2017, 14: 203-207. PMID: 28481605, DOI: 10.1037/ser0000083.Peer-Reviewed Original ResearchConceptsSpecialty mental health clinicsMental health clinicsHealth clinicsRetrospective cohort study designVeterans AffairsSpecialty mental health careCohort study designVA medical recordsDrug use disordersMental health careVA homeless servicesClinical predictorsProspective studyMedical recordsDisorders ClinicInternational ClassificationUse disordersVA facilitiesU.S. veteransEarly signsStudy designVA effortsClinicHealth careIncidence
2016
Substance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design
Zhang C, Liu Y, Sun X, Wang J, Lu HY, He X, Zhang H, Ruan YH, Shao Y, Vermund SH, Qian HZ. Substance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design. AIDS Care 2016, 29: 644-653. PMID: 27832699, PMCID: PMC5350012, DOI: 10.1080/09540121.2016.1255709.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsCohort study designSubstance useStudy designHIV-positive MSMHIV-positive menGeneralized Estimating Equation modelsFemale sex partnersRapid HIV transmissionMale sexual partnersRigorous study designsSexual risk behaviorsCurrent studySeronegative counterpartsSeropositive menSeropositive partnersHIV transmissionMean agePotential confoundersRisk factorsHigh riskRisk populationsSex partnersUnprotected sexRisk behaviors
2015
Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts
Bellan SE, Dushoff J, Galvani AP, Meyers LA. Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts. PLOS Medicine 2015, 12: e1001801. PMID: 25781323, PMCID: PMC4363602, DOI: 10.1371/journal.pmed.1001801.Peer-Reviewed Original ResearchConceptsElevated viral loadAcute phaseViral load trajectoriesSexual network structureViral loadStudy terminationExclusion criteriaRetrospective cohort study designStudy designAcute phase durationSerodiscordant heterosexual couplesRetrospective cohort dataCohort study designProportion of transmissionCourse of infectionRetrospective cohortAntiretroviral treatmentSerodiscordant couplesChronic phaseSimulated cohortRelative hazardCohort dataCohortWide credibility intervalsAdditional risk
2004
Breastfeeding and maternal HIV-1 disease progression and mortality
Sedgh G, Spiegelman D, Larsen U, Msamanga G, Fawzi WW. Breastfeeding and maternal HIV-1 disease progression and mortality. AIDS 2004, 18: 1043-1049. PMID: 15096808, DOI: 10.1097/00002030-200404300-00013.Peer-Reviewed Original ResearchConceptsHIV-1 disease progressionCD4 cell countDisease progressionCell countHigher CD4 cell countsLow CD4 cell countsCox proportional hazards modelHealth of HIVCohort study designExcessive weight lossProportional hazards modelPartial breastfeedingRelative riskHazards modelInsufficient evidenceBreastfeedingMultivariate analysisStudy designWeight lossWomenProgressionDar es SalaamHIVDeathAssociation
2002
Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin
Fung TT, Spiegelman D, Egan KM, Giovannucci E, Hunter DJ, Willett WC. Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin. International Journal Of Cancer 2002, 103: 110-115. PMID: 12455062, DOI: 10.1002/ijc.10798.Peer-Reviewed Original ResearchConceptsCases of SCCHEALTHY studyProspective cohort study designMale health professionalsHealth Professionals FollowCohort study designIntake of vitaminsSquamous cell carcinomaSignificant inverse associationDevelopment of SCCImportant protective roleIncidence of SCCBiennial questionnairesProfessionals FollowMultivariate adjustmentCell carcinomaSCC incidenceDietary factorsInverse associationMedical recordsRisk factorsRelative riskLarge cohortCarotenoid intakeSun exposure
1999
Methodological issues in the study of rare exposures and rare outcomes in perinatal epidemiology
Bracken M. Methodological issues in the study of rare exposures and rare outcomes in perinatal epidemiology. Journal Of Allergy And Clinical Immunology 1999, 103: s354-s355. PMID: 9949337, DOI: 10.1016/s0091-6749(99)70262-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1996
The Incident Patient Cohort Study Design With Uncontrolled Dose
GOTCH F, GENTILE D, KEEN M, AMERLING R, FOLKERT V, KLIGER A, SHAPIRO W. The Incident Patient Cohort Study Design With Uncontrolled Dose. ASAIO Journal 1996, 42: m514-517. PMID: 8944932, DOI: 10.1097/00002480-199609000-00039.Peer-Reviewed Original ResearchConceptsPeritoneal dialysisContinuous ambulatory peritoneal dialysisAmbulatory peritoneal dialysisCohort study designClinical outcome studiesRenal urea clearanceDialysis prescriptionSingle dosesDose equivalencyRelative riskDialysis doseMortality riskOutcome studiesDose levelsUrea clearanceStudy designMonth intervalsD responseHemodialysisDialysisDoseDosesRiskMortalityWide variance
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