2025
Monitoring molecular markers associated with antimalarial drug resistance in south-east Senegal from 2021 to 2023
Wade A, Sene S, Caspar E, Diallo F, Platon L, Thiebaut L, Pouye M, Ba A, Thiam L, Fall M, Sadio B, Desamours I, Guerra N, Hagadorn K, Amambua-Ngwa A, Bei A, Vigan-Womas I, Ménard D, Mbengue A. Monitoring molecular markers associated with antimalarial drug resistance in south-east Senegal from 2021 to 2023. Journal Of Antimicrobial Chemotherapy 2025, 80: 828-839. PMID: 39846779, PMCID: PMC11879165, DOI: 10.1093/jac/dkaf006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntimalarialsArtemisininsChildChild, PreschoolDrug CombinationsDrug ResistanceFemaleHumansMalaria, FalciparumMaleMembrane Transport ProteinsMiddle AgedMultidrug Resistance-Associated ProteinsMutationPlasmodium falciparumProtozoan ProteinsPyrimethamineSenegalSulfadoxineTetrahydrofolate DehydrogenaseYoung AdultConceptsArtemisinin-based combination therapyMolecular markers associated with antimalarial drug resistanceArtemisinin-based combination therapy efficacyP. falciparum infectionSulfadoxine-pyrimethamine resistanceAntimalarial drug resistanceInvestigated gene polymorphismsCQ-RResistance in vitroVenous blood samplesClinical outcome studiesI356TK76TPfcrt mutationsChloroquine resistanceAntimalarial resistancePfmdr-1CQ useMalaria eliminationCombination therapyResistance surveillanceGene polymorphismsPlasmodium falciparumDrug resistanceAmplicon deep sequencing
2024
Biomarkers vs Machines: The Race to Predict Acute Kidney Injury
Ghazi L, Farhat K, Hoenig M, Durant T, El-Khoury J. Biomarkers vs Machines: The Race to Predict Acute Kidney Injury. Clinical Chemistry 2024, 70: 805-819. PMID: 38299927, DOI: 10.1093/clinchem/hvad217.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAcute kidney injuryEarly diagnosisInsulin-like growth factor-binding protein 7Prediction of acute kidney injuryGrowth factor-binding protein 7Detect acute kidney injuryNeutrophil Gelatinase-Associated LipocalinAcute kidney injury detectionClinical practiceIrreversible kidney damageClinical outcome studiesImminent AKISerum creatinineKidney injuryInjury markersPediatric populationCystatin CTissue inhibitorHospitalized patientsClinical useKidney damageRegulatory approvalProtein 7BiomarkersOutcome studies
2022
Workers’ Compensation Patients Improved After Hip Arthroscopy for Labral Tears: A 5-Year Outcome Propensity Score–Matched Study
Sabetian PW, Monahan PF, Fox JD, Jimenez AE, Maldonado DR, Saks BR, Ankem HK, Lall AC, Domb BG. Workers’ Compensation Patients Improved After Hip Arthroscopy for Labral Tears: A 5-Year Outcome Propensity Score–Matched Study. The American Journal Of Sports Medicine 2022, 50: 1281-1290. PMID: 35286179, DOI: 10.1177/03635465221078620.Peer-Reviewed Original ResearchConceptsMaximum outcome improvement satisfaction thresholdPatient acceptable symptom stateHip arthroscopyLabral tearsWC patientsControl groupWC claimsWC statusCompensation statusFemoroacetabular impingementWC groupWC casesPropensity score-matched studyPropensity score-matched control groupOutcomes of patientsWorkers' compensation statusAcceptable symptom statePrimary hip arthroscopyHip arthroscopic surgeryPatient-reported outcomesClinical outcome studiesLevel of evidenceTotal hip arthroplastyCompensation patientsHOS-SSS
2021
Capsular Repair May Improve Outcomes in Patients Undergoing Hip Arthroscopy for Femoroacetabular Impingement: A Systematic Review of Comparative Outcome Studies
Owens JS, Jimenez AE, Shapira J, Saks BR, Glein RM, Maldonado DR, Ankem HK, Sabetian PW, Lall AC, Domb BG. Capsular Repair May Improve Outcomes in Patients Undergoing Hip Arthroscopy for Femoroacetabular Impingement: A Systematic Review of Comparative Outcome Studies. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2021, 37: 2975-2990. PMID: 33887416, DOI: 10.1016/j.arthro.2021.03.063.Peer-Reviewed Original ResearchConceptsPatient-reported outcome scoresUnrepaired capsulotomyCapsular repairOutcome studiesComparative outcome studiesHip arthroscopySystematic reviewUnrepaired groupLevel INon-randomized studiesPatient-reported outcomesGood patient-reported outcome scoresFemoroacetabular impingement syndromeLevel III studiesClinical outcome studiesPartial repairMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsCapsular management techniquesIII studyReoperation rateImpingement syndromeOutcome scoresImaging outcomesMethodological Index
2017
Two Decades of Cardiovascular Trials With Primary Surrogate Endpoints: 1990–2011
Bikdeli B, Punnanithinont N, Akram Y, Lee I, Desai NR, Ross JS, Krumholz HM. Two Decades of Cardiovascular Trials With Primary Surrogate Endpoints: 1990–2011. Journal Of The American Heart Association 2017, 6: e005285. PMID: 28325713, PMCID: PMC5524035, DOI: 10.1161/jaha.116.005285.Peer-Reviewed Original ResearchConceptsClinical outcome trialsOutcome trialsEndpoint trialsPrimary endpointCardiovascular trialsClinical outcome studiesClinical outcomesSurrogate markerPatient's perspectiveSurrogate endpointsOutcome studiesNew England JournalSample cohortTrial resultsTrialsSurrogate trialsEndpointPositive resultsAmerican MedicalInterventionHigh-impact journalsCohort
2003
HER-2/neu testing in breast cancer.
Ross JS, Fletcher JA, Bloom KJ, Linette GP, Stec J, Clark E, Ayers M, Symmans WF, Pusztai L, Hortobagyi GN. HER-2/neu testing in breast cancer. American Journal Of Clinical Pathology 2003, 120 Suppl: s53-71. PMID: 15298144, DOI: 10.1309/949fpq1aq3p0rlc0.Peer-Reviewed Original ResearchConceptsBreast cancerNeu testingNeu statusProspective clinical outcome studyTrastuzumab-based therapyMajor clinical trialsEarly clinical stagePredictors of responseClinical outcome studiesBreast cancer specimensAdvanced diseaseClinical responseClinical stageClinical trialsStandards of practiceCancer specimensImmunohistochemical analysisOutcome studiesPotential efficacyCancerSitu hybridization techniqueRecent evidenceTherapySitu hybridization methodExcellent results
1996
The Incident Patient Cohort Study Design With Uncontrolled Dose
GOTCH F, GENTILE D, KEEN M, AMERLING R, FOLKERT V, KLIGER A, SHAPIRO W. The Incident Patient Cohort Study Design With Uncontrolled Dose. ASAIO Journal 1996, 42: m514-517. PMID: 8944932, DOI: 10.1097/00002480-199609000-00039.Peer-Reviewed Original ResearchConceptsPeritoneal dialysisContinuous ambulatory peritoneal dialysisAmbulatory peritoneal dialysisCohort study designClinical outcome studiesRenal urea clearanceDialysis prescriptionSingle dosesDose equivalencyRelative riskDialysis doseMortality riskOutcome studiesDose levelsUrea clearanceStudy designMonth intervalsD responseHemodialysisDialysisDoseDosesRiskMortalityWide variance
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